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COBRA: a novel compound discovery pipeline for rapid and cost-effective identification of bioactives with health beneficial effects in Brazilian crops

Grant number: 15/50333-1
Support Opportunities:Research Projects - Thematic Grants
Duration: April 01, 2016 - July 31, 2021
Field of knowledge:Agronomical Sciences - Food Science and Technology - Food Science
Convênio/Acordo: Innovation Fund Denmark
Principal Investigator:Glaucia Maria Pastore
Grantee:Glaucia Maria Pastore
Principal researcher abroad: Karsten Kristiansen
Institution abroad: University of Copenhagen, Copenhagen, Denmark
Host Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated scholarship(s):19/12244-8 - Effect of jabuticaba (Plinia jaboticaba) peel supplementation on metabolic profile in obese pre-diabetic subjects: a randomized, double-blinded, controlled trial, BP.DR

Abstract

These project aims to catalogue these bioactive compounds through a combination of chemoinformatics analyses, comprehensive data mining, and de-novo discovery and structural characterization of novel compounds. A comprehensive digitalized library of compounds will increase the knowledge and potential use of Brazilian native crops for the development of novel supplements/food with documented beneficial health promoting properties. Both the database and chemoinformatics tool developed in the project will serve as a resource for both public and private research. Finally, the project is expected to result in at least one new product using ingredients from the studied Brazilian crops. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Articles published in other media outlets ( ):
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (127)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
APARECIDA PEREIRA, ANA PAULA; FIGUEIREDO ANGOLINI, CELIO FERNANDO; ADANI, HELOISA BANIN; SOUZA USBERTI, FRANCIANE COLARES; PAULINO, BRUNO NICOLAU; PEDROSA SILVA CLERICI, MARIA TERESA; NERI-NUMA, IRAMAIA ANGELICA; ALVES MORO, THAISA DE MENEZES; EBERLIN, MARCOS NOGUEIRA; PASTORE, GLAUCIA MARIA. Impact of ripening on the health-promoting components from fruta-do-lobo (Solanum lycocarpum St. Hill). Food Research International, v. 139, . (19/08853-9, 15/50333-1)
DE SOUZA, FLORISVALDO GAMA; NATHIA-NEVES, GRAZIELLE; DE ARAUJO, FABIO FERNANDES; DIAS AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; NERI-NUMA, IRAMAIA ANGELICA; CATHARINO, RODRIGO RAMOS; DE ALENCAR, SEVERINO MATIAS; DE ALMEIDA MEIRELES, MARIA ANGELA; PASTORE, GLAUCIA MARIA. valuation of antioxidant capacity, fatty acid profile, and bioactive compounds from buritirana (Mauritiella armata Mart.) oil: A little-explored native Brazilian frui. Food Research International, v. 142, . (15/50333-1, 19/05718-3)
BARROS HELENA, D. F. Q.; BASEGGIO ANDRESSA, M.; ANGOLINI CELIO, F. F.; PASTORE GLAUCIA, M.; CAZARIN CINTHIA, B. B.; MAROSTICA-JUNIOR MARIO, R.. Influence of different types of acids and pH in the recovery of bioactive compounds in Jabuticaba peel (Plinia cauliflora). Food Research International, v. 124, n. SI, p. 16-26, . (17/04231-8, 15/50333-1)
LAMAS, CELINA A.; KIDO, LARISSA A.; HERMES, TULIO A.; NOGUEIRA-LIMA, ELLEN; MINATEL, ELAINE; COLLARES-BUZATO, CARLA B.; MAROSTICA JR, MARIO R.; CAGNON, VALERIA H. A.. Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. PROSTATE, v. 80, n. 11, . (18/11069-5, 15/50333-1, 15/25714-1)
APARECIDA PEREIRA, ANA PAULA; CHATAGNIER LAURETTI, LEONARDO BORGES; ALVARENGA, VERONICA ORTIZ; PAULINO, BRUNO NICOLAU; FIGUEIREDO ANGOLINI, CELIO FERNANDO; NERI-NUMA, IRAMAIA ANGELICA; ORLANDO, EDUARDO ADILSON; LIMA PALLONE, JULIANA AZEVEDO; SANT'ANA, ANDERSON S.; PASTORE, GLAUCIA MARIA. Evaluation of fruta-do-lobo (Solanum lycocarpum St. Hill) starch on the growth of probiotic strains. Food Research International, v. 133, . (15/50333-1)
LOPES DO CARMO, MONICA CRISTINA; MARTINS, ISABELA MATEUS; MAGALHAES, ANA ELISA RAMOS; MAROSTICA JUNIOR, MARIO ROBERTO; MACEDO, JULIANA ALVES. Passion fruit (Passiflora edulis) leaf aqueous extract ameliorates intestinal epithelial barrier dysfunction and reverts inflammatory parameters in Caco-2 cells monolayer. Food Research International, v. 133, . (15/50333-1)
PRADO, LIVIA GARCIA; ARRUDA, HENRIQUE SILVANO; PEIXOTO ARAUJO, NAYARA MACEDO; DE OLIVEIRA BRAGA, LUCIA ELAINE; BANZATO, THAIS PETROCHELLI; PEREIRA, GUSTAVO ARAUJO; FIGUEIREDO, MARIANA CECCHETTO; TASCA GOIS RUIZ, ANA LUCIA; EBERLIN, MARCOS NOGUEIRA; DE CARVALHO, JOAO ERNESTO; et al. Antioxidant, antiproliferative and healing properties of araticum (Annona crassiflora Mart.) peel and seed. Food Research International, v. 133, . (16/15746-6, 18/10608-0, 15/50333-1)
TARONE, ADRIANA GADIOLI; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, MARIO ROBERTO. Anthocyanins: New techniques and challenges in microencapsulation. Food Research International, v. 133, . (15/50333-1)
MACHADO, ANA PAULA DA FONSECA; GERALDI, MARINA VILAR; NASCIMENTO, ROBERTO DE PAULA DO; MOYA, AMANDA MARIA TOMAZINI MUNHOZ; VEZZA, TERESA; DIEZ-ECHAVE, PATRICIA; JUAN GALVAZ, JULIO; CAZARIN, CINTHIA BAU BETIM; MAROSTICA JUNIOR, MARIO ROBERTO. Polyphenols from food by-products: An alternative or complementary therapy to IBD conventional treatments. Food Research International, v. 140, . (18/11069-5, 19/12244-8, 15/50333-1, 17/23657-6)
ARAUJO, NAYARA MACEDO PEIXOTO; ARRUDA, HENRIQUE SILVANO; FARIAS, DAVID DE PAULO; MOLINA, GUSTAVO; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA. Plants from the genus Eugenia as promising therapeutic agents for the management of diabetes mellitus: A review. Food Research International, v. 142, . (20/00225-6, 18/10608-0, 15/50333-1)
PAULINO, BRUNO N.; SALES, ADONES; FELIPE, LORENA DE OLIVEIRA; PASTORE, GLAUCIA M.; MOLINA, GUSTAVO; BICAS, JULIANO L.. Biotechnological production of non-volatile flavor compounds. CURRENT OPINION IN FOOD SCIENCE, v. 41, p. 26-35, . (15/50333-1, 16/21619-7)
PAULINO, BRUNO N.; MOLINA, GUSTAVO; PASTORE, GLAUCIA M.; BICAS, JULIANO L.. Current perspectives in the biotechnological production of sweetening syrups and polyols. CURRENT OPINION IN FOOD SCIENCE, v. 41, p. 36-43, . (15/50333-1, 16/21619-7)
VUOLO, MILENA MORANDI; BATISTA, ANGELA GIOVANA; TELLES BIASOTO, ALINE CAMARAO; CORREA, LUIZ CLAUDIO; MAROSTICA JUNIOR, MARIO ROBERTO; LIU, RUI HAI. Red-jambo peel extract shows antiproliferative activity against HepG2 human hepatoma cells. Food Research International, v. 124, p. 8-pg., . (15/50333-1)
APARECIDA PEREIRA, ANA PAULA; FIGUEIREDO ANGOLINI, CELIO FERNANDO; ADANI, HELOISA BANIN; SOUZA USBERTI, FRANCIANE COLARES; PAULINO, BRUNO NICOLAU; PEDROSA SILVA CLERICI, MARIA TERESA; NERI-NUMA, IRAMAIA ANGELICA; ALVES MORO, THAISA DE MENEZES; EBERLIN, MARCOS NOGUEIRA; PASTORE, GLAUCIA MARIA. Impact of ripening on the health-promoting components from fruta-do-lobo (Solanum lycocarpum St. Hill). Food Research International, v. 139, p. 9-pg., . (19/08853-9, 15/50333-1)
DA SILVA-MAIA, JULIANA KELLY; NAGALINGAM, ARUMUGAM; CAZARIN, CINTHIA BAIL BETIM; MAROSTICA JR, MARIO ROBERTO; SHARMA, DIPALI. Jaboticaba (Myrciaria jaboticaba) peel extracts induce reticulum stress and apoptosis in breast cancer cells. FOOD CHEMISTRY: MOLECULAR SCIENCES, v. 6, p. 8-pg., . (19/13465-8, 15/50333-1, 18/11069-5, 15/13320-9)
NERI-NUMA, IRAMAIA ANGELICA; PESSOA, MARINA GABRIEL; PAULINO, BRUNO NICOLAU; PASTORE, GLAUCIA MARIA. Genipin: A natural blue pigment for food and health purposes. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 67, p. 271-279, . (15/50333-1)
APARECIDA PEREIRA, ANA PAULA; FIGUEIREDO ANGOLINI, CELIO FERNANDO; DE SOUZA-SPORKENS, JANE CRISTINA; DA SILVA, TOMAZ ANTONIO; FRANCO DE OLIVEIRA, HELENA COUTINHO; PASTORE, GLAUCIA MARIA. Brazilian sunberry (Solanum oocarpum Sendtn): Alkaloid composition and improvement of mitochondrial functionality and insulin secretion of INS-1E cells. Food Research International, v. 148, . (19/08853-9, 17/17728-8, 15/50333-1)
PEIXOTO ARAUJO, NAYARA MACEDO; ARRUDA, HENRIQUE SILVANO; DOS SANTOS, FABIO NEVES; DE MORAIS, DAMILA RODRIGUES; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA. LC-MS/MS screening and identification of bioactive compounds in leaves, pulp and seed from Eugenia calycina Cambess. Food Research International, v. 137, . (15/50333-1, 18/10608-0, 17/09726-5, 16/22577-6)
ALEXANDRINO, THAIS DOLFINI; TOMAZINI MUNHOZ MOYA, AMANDA MARIA; MADUREIRA DE MEDEIROS, TIAGO DANIEL; MORARI, JOSEANE; VELLOSO, LICIO AUGUSTO; LEAL, RAQUEL FRANCO; MAROSTICA, MARIO ROBERTO; PASTORE, GLAUCIA MARIA; BETIM CAZARIN, CINTHIA BAU; BICAS, JULIANO LEMOS. Anti-inflammatory effects of monoterpenoids in rats with TNBS-induced colitis. PHARMANUTRITION, v. 14, . (16/21619-7, 15/50333-1, 15/13320-9, 18/11069-5)
NERI-NUMA, IRAMAIA ANGELICA; BETIM CAZARIN, CINTHIA BAU; TASCA GOIS RUIZ, ANA LUCIA; PAULINO, BRUNO NICOLAU; MOLINA, GUSTAVO; PASTORE, GLAUCIA MARIA. Targeting flavonoids on modulation of metabolic syndrome. Journal of Functional Foods, v. 73, . (15/50333-1)
BATISTA, ANGELA GIOVANA; DA SILVA-MAIA, JULIANA KELLY; MENDONCA, MONIQUE CULTURATO P.; SOARES, EDILENE SIQUEIRA; LIMA, GLAUCIA CARIELO; BOGUSZ JUNIOR, STANISLAU; DA CRUZ-HOFLING, MARIA ALICE; MAROSTICA JUNIOR, MARIO ROBERTO. Jaboticaba berry peel intake increases short chain fatty acids production and prevent hepatic steatosis in mice fed high-fat diet. Journal of Functional Foods, v. 48, p. 266-274, . (15/50333-1)
VUOLO, MILENA MORANDI; LIMA, GLAUCIA CARIELO; BATISTA, ANGELA GIOVANA; BETIM CARAZIN, CINTHIA BAU; CINTRA, DENNYS ESPER; PRADO, MARCELO ALEXANDRE; MAROSTICA JUNIOR, MARIO ROBERTO. Passion fruit peel intake decreases inflammatory response and reverts lipid peroxidation and adiposity in diet-induced obese rats. Nutrition Research, v. 76, p. 106-117, . (18/11069-5, 12/12322-0, 15/50333-1)
PEREIRA, GUSTAVO ARAUJO; SILVA, ERIC KEVEN; PEIXOTO ARAUJO, NAYARA MACEDO; ARRUDA, HENRIQUE SILVANO; MEIRELES, M. ANGELA A.; PASTORE, GLAUCIA MARIA. Mutamba seed mucilage as a novel emulsifier: Stabilization mechanisms, kinetic stability and volatile compounds retention. FOOD HYDROCOLLOIDS, v. 97, . (15/22226-6, 15/50333-1)
DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; DIAS-AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; DE SOUZA, FLORISVALDO GAMA; CATHARINO, RODRIGO RAMOS; DO SACRAMENTO, CELIO KERSUL; PASTORE, GLAUCIA MARIA. Chemical characterization of Eugenia stipitata: A native fruit from the Amazon rich in nutrients and source of bioactive compounds. Food Research International, v. 139, . (20/00225-6, 15/50333-1, 19/05718-3)
SANZANA, SIGRID; RODRIGUEZ, LYANNE; BARRAZA BARRIONUEVO, HAYLEEN; ALBORNOZ POBLETE, CESAR; MAROSTICA JUNIOR, MARIO ROBERTO; FUENTES, EDUARDO; PALOMO, IVAN. ntiplatelet Activity of Cucurbita maxim. JOURNAL OF MEDICINAL FOOD, . (18/11069-5, 15/50333-1, 15/13320-9)
PEREIRA, GUSTAVO ARAUJO; ARRUDA, HENRIQUE SILVANO; DE MORAIS, DAMILA RODRIGUES; PEIXOTO ARAUJO, NAYARA MACEDO; PASTORE, GLAUCIA MARIA. Mutamba (Guazuma ulmifolia Lam.) fruit as a novel source of dietary fibre and phenolic compounds. Food Chemistry, v. 310, . (15/50333-1)
PASCOAL, GABRIELA DE FREITAS LAIBER; GERALDI, MARINA VILAR; MAROSTICA, MARIO ROBERTO, JR.; ONG, THOMAS PRATES. Effect of Paternal Diet on Spermatogenesis and Offspring Health: Focus on Epigenetics and Interventions with Food Bioactive Compounds. NUTRIENTS, v. 14, n. 10, p. 18-pg., . (15/13320-9, 18/11069-5, 19/13465-8, 15/50333-1, 19/12244-8, 13/07914-8)
PASTORE, GLAUCIA MARIA. Inulin thermal stability in prebiotic carbohydrate-enriched araticum whey beverage. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 128, . (15/22226-6, 15/50333-1)
DA SILVA-MAIA, JULIANA KELLY; BATISTA, ANGELA GIOVANA; CORREA, LUIZ CLAUDIO; LIMA, GLAUCIA CARIELO; BOGUSZ JUNIOR, STANISLAU; MAROSTICA JUNIOR, MARIO ROBERTO. Aqueous extract of berry (Plinia jaboticaba) byproduct modulates gut microbiota and maintains the balance on antioxidant defense system in rats. JOURNAL OF FOOD BIOCHEMISTRY, v. 43, n. 2, . (15/50333-1)
PAULINO, BRUNO N.; PESSOA, MARINA G.; MOLINA, GUSTAVO; KAUPERT NETO, ANTONIO A.; OLIVEIRA, JULIANA V. C.; MANO, MARIO C. R.; PASTORE, GLAUCIA M.. Biotechnological production of value-added compounds by ustilaginomycetous yeasts. Applied Microbiology and Biotechnology, v. 101, n. 21, p. 7789-7809, . (15/50333-1)
NERI-NUMA, IRAMAIA ANGELICA; FIGUEIREDO ANGOLINI, CELIO FERNANDO; BICAS, JULIANO LEMOS; TASCA GOIS RUIZ, ANA LUCIA; PASTORE, GLAUCIA MARIA. Iridoid blue-based pigments of Genipa americana L. (Rubiaceae) extract: Influence of pH and temperature on color stability and antioxidant capacity during in vitro simulated digestion. Food Chemistry, v. 263, p. 300-306, . (15/50333-1)
PEREIRA, GUSTAVO ARAUJO; ARRUDA, HENRIQUE SILVANO; DE MORAIS, DAMILA RODRIGUES; EBERLIN, MARCOS NOGUEIRA; PASTORE, GLAUCIA MARIA. Carbohydrates, volatile and phenolic compounds composition, and antioxidant activity of calabura (Muntingia calabura L.) fruit. Food Research International, v. 108, p. 264-273, . (16/23157-0, 15/50333-1)
NERI-NUMA, IRAMAIA ANGELICA; SORIANO SANCHO, RENATA A.; APARECIDA PEREIRA, ANA PAULA; PASTORE, GLAUCIA MARIA. Small Brazilian wild fruits: Nutrients, bioactive compounds, health-promotion properties and commercial interest. Food Research International, v. 103, p. 345-360, . (15/50333-1)
BALDINI, TATIANA FERRARI; NERI-NUMA, IRAMAIA ANGELICA; DO SACRAMENTO, CELIO KERSUL; SCHMIELE, MARCIO; ANDRE BOLINI, HELENA MARIA; PASTORE, GLAUCIA MARIA; BICAS, JULIANO LEMOS. Elaboration and Characterization of Apple Nectars Supplemented with Araca-boi (Eugenia stipitata Mac Vaugh-Myrtaceae). BEVERAGES, v. 3, n. 4, . (15/50333-1)
LAMAS, C. A.; KIDO, L. A.; MONTICO, F.; COLLARES-BUZATO, C. B.; MAROSTICA, JR., M. R.; CAGNON, V. H. A.. A jaboticaba extract prevents prostatic damage associated with aging and high-fat diet intake. FOOD & FUNCTION, v. 11, n. 2, p. 1547-1559, . (15/50333-1, 15/25714-1, 10/05262-5)
DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Underutilized plants of the Cactaceae family: Nutritional aspects and technological applications. Food Chemistry, v. 362, . (15/50333-1, 20/00225-6)
TARONE, ADRIANA GADIOLI; SILVA, ERIC KEVEN; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, JR., MARIO ROBERTO. Inulin/fructooligosaccharides/pectin-based structured systems: Promising encapsulating matrices of polyphenols recovered from jabuticaba peel. FOOD HYDROCOLLOIDS, v. 111, . (15/50333-1, 15/13320-9)
BALLARD, CINTIA REIS; DOS SANTOS, ELISVANIA FREITAS; DUBOIS, MARIE-JULIE; PILON, GENEVIEVE; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, MARIO ROBERTO; MARETTE, ANDRE. Two polyphenol-rich Brazilian fruit extracts protect from diet-induced obesity and hepatic steatosis in mice. FOOD & FUNCTION, v. 11, n. 10, p. 8800-8810, . (15/50333-1)
MACHADO, ANA PAULA DA FONSECA; DO NASCIMENTO, ROBERTO DE PAULA; ALVES, MARIANA DA ROCHA; REGUENGO, LIVIA MATEUS; MAROSTICA JUNIOR, MARIO ROBERTO. razilian tucuma-do-Amazonas (Astrocaryum aculeatum) and tucuma-do-Para (Astrocaryum vulgare) fruits: bioactive composition, health benefits, and technological potentia. Food Research International, v. 151, . (18/11069-5, 19/25048-2, 19/03228-9, 17/23657-6, 15/50333-1, 15/13320-9)
DE PAULA DO NASCIMENTO, ROBERTO; DA FONSECA MACHADO, ANA PAULA; LIMA, VERENA SILVA; TOMAZINI MUNHOZ MOYA, AMANDA MARIA; REGUENGO, LIVIA MATEUS; BOGUSZ JUNIOR, STANISLAU; LEAL, RAQUEL FRANCO; CAO-NGOC, PHU; ROSSI, JEAN CHRISTOPHE; LECLERCQ, LAURENT; et al. Chemoprevention with a tea from hawthorn (Crataegus oxyacantha) leaves and flowers attenuates colitis in rats by reducing inflammation and oxidative stress. FOOD CHEMISTRY-X, v. 12, . (15/50333-1, 15/13320-9, 18/11069-5, 17/23657-6)
ARRUDA, HENRIQUE SILVANO; PASTORE, GLAUCIA MARIA. Araticum (Annona crassiflora Mart.) as a source of nutrients and bioactive compounds for food and non-food purposes: A comprehensive review. Food Research International, v. 123, p. 450-480, . (15/50333-1)
MAURER, LUANA HASELEIN; BETIM CAZARIN, CINTHIA BAU; QUATRIN, ANDREIA; NICHELLE, SABRINA MARAFIGA; MINUZZI, NATALIA MACHADO; TEIXEIRA, CIBELE FERREIRA; MANICA DA CRUZ, IVANA BEATRICE; MAROSTICA JUNIOR, MARIO ROBERTO; EMANUELLI, TATIANA. Dietary fiber and fiber-bound polyphenols of grape peel powder promote GSH recycling and prevent apoptosis in the colon of rats with TNBS-induced colitis. Journal of Functional Foods, v. 64, . (15/50333-1)
NERI-NUMA, IRAMAIA ANGELICA; DELLATORRE, ADRIANA; ORIANI, VIVIAN BOESSO; FRANCH, JR., GILBERTO CARLOS; FIGUEIREDO ANGOLINI, CELIO FERNANDO; HUBINGER, MIRIAM DUPAS; TASCA GOIS RUIZ, ANA LUCIA; PASTORE, GLAUCIA MARIA. In vitro bioactivity approach of unripe genipap (Genipa americana L., Rubiaceae) fruit extract and its solid lipid microparticle. Food Research International, v. 127, . (15/50333-1)
QUATRIN, ANDREIA; RAMPELOTTO, CRISTINE; PAULETTO, ROBERSON; MAURER, LUANA HASELEIN; NICHELLE, SABRINA MARAFIGA; KLEIN, BRUNA; RODRIGUES, RENATA FRITZSCHE; MAROSTICA JUNIOR, MARIO ROBERTO; FONSECA, BRUNA DE SOUZA; DE MENEZES, CRISTIANO RAGAGNIN; et al. Bioaccessibility and catabolism of phenolic compounds from jaboticaba (Myrciaria trunciflora) fruit peel during in vitro gastrointestinal digestion and colonic fermentation. Journal of Functional Foods, v. 65, . (18/11069-5, 15/50333-1)
PEREIRA, GUSTAVO ARAUJO; SILVA, ERIC KEVEN; PEIXOTO ARAUJO, NAYARA MACEDO; ARRUDA, HENRIQUE SILVANO; MEIRELES, M. ANGELA A.; PASTORE, GLAUCIA MARIA. Obtaining a novel mucilage from mutamba seeds exploring different high - intensity ultrasound process conditions. ULTRASONICS SONOCHEMISTRY, v. 55, p. 332-340, . (15/22226-6, 15/50333-1)
ARRUDA, HENRIQUE SILVANO; PEREIRA, GUSTAVO ARAUJO; DE MORAIS, DAMILA RODRIGUES; EBERLIN, MARCOS NOGUEIRA; PASTORE, GLAUCIA MARIA. Determination of free, esterified, glycosylated and insoluble-bound phenolics composition in the edible part of araticum fruit (Annona crassiflora Mart.) and its by-products by HPLC-ESI-MS/MS. Food Chemistry, v. 245, p. 738-749, . (16/23157-0, 15/50333-1)
GERALDI, MARINA VILAR; CAZARIN, CINTHIA BAU BETIM; CRISTIANINI, MARCELO; JUNQUEIRA VASQUES, ANA CAROLINA; GELONEZE, BRUNO; MAROSTICA JUNIOR, MARIO ROBERTO. Jabuticaba juice improves postprandial glucagon-like peptide-1 and antioxidant status in healthy adults: a randomised crossover trial. BRITISH JOURNAL OF NUTRITION, v. 128, n. 8, p. 10-pg., . (15/50333-1, 19/12244-8)
DO NASCIMENTO, ROBERTO DE PAULA; POLEZI, GABRIELE; RIZZATO, JULIA SOTO; BATISTA, PATRICIA BERILLI; DOS SANTOS, NATHALIA MEDINA; LOUBET FILHO, PAULO SERGIO; REGUENGO, LIVIA MATEUS; MORARI, JOSEANE; JUNIOR, STANISLAU BOGUSZ; RIBEIRO PAIOTTI, ANA PAULA; et al. Brazilian berries prevent colitis induced in obese mice by reducing the clinical signs and intestinal damage. FOOD BIOSCIENCE, v. 44, n. B, . (15/50333-1, 15/13320-9, 18/11069-5)
CARNEIRO, MARA JUNQUEIRA; PINHEIRO, GUILHERME PEREZ; BASEGGIO, ANDRESSA MARA; MAROSTICA JR, MARIO ROBERTO; SAWAYA, ALEXANDRA CHRISTINE HELENA FRANKLAND. Chemical Composition and Antioxidant Activity of Essential Oil from Male and Female Schinus terebinthifolius. PHARMACOGNOSY RESEARCH, v. 15, n. 3, p. 8-pg., . (15/13320-9, 16/11524-9, 22/09493-9, 15/50333-1, 19/13465-8, 18/11069-5)
BASEGGIO, ANDRESSA MARA; COIMBRA NUNEZ, CARLA EVELYN; VICENTE DRAGANO, NATHALIA ROMANELLI; LAMAS, CELINA ALMEIDA; DE CAMPOS BRAGA, PATRICIA APARECIDA; LENQUISTE, SABRINA ALVES; REYES REYES, FELIX GUILLERMO; ALVES CAGNON, VALERIA HELENA; MAROSTICA JUNIOR, MARIO ROBERTO. Jaboticaba peel extract decrease autophagy in white adipose tissue and prevents metabolic disorders in mice fed with a high-fat diet. PHARMANUTRITION, v. 6, n. 4, p. 10-pg., . (13/13480-0, 15/20766-3, 15/50333-1)
DE CAMARGO, ADRIANO COSTA; SCHWEMBER, ANDRES R.; PARADA, ROBERTO; GARCIA, SANDRA; MAROSTICA JUNIOR, MARIO ROBERTO; FRANCHIN, MARCELO; BISMARA REGITANO-D'ARCE, MARISA APARECIDA; SHAHIDI, FEREIDOON. Opinion on the Hurdles and Potential Health Benefits in Value-Added Use of Plant Food Processing By-Products as Sources of Phenolic Compounds. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 19, n. 11, p. 47-pg., . (15/50333-1, 16/15563-9, 12/17683-0, 15/00336-4)
GERALDI, MARINA V.; CAZARIN, CINTHIA B. B.; VASQUES, ANA CAROLINA J.; NETO, BRUNO G.; MAROSTICA JUNIOR, MARIO R.. Jabuticaba Juice Improve Glucagon-Like Peptide-1 in Healthy Participants: Results from a Pilot, Single-Blinded, Randomized Controlled Trial. Diabetes, v. 69, p. 2-pg., . (15/50333-1)
DE OLIVEIRA, WILLIARA QUEIROZ; NERI-NUMA, IRAMAIA ANGELICA; ARRUDA, HENRIQUE SILVANO; LOPES, AMANDA TIBAES; PELISSARI, FRANCIELE MARIA; BARROS, FRANCISCO FABIO CAVALCANTE; PASTORE, GLAUCIA MARIA. Special emphasis on the therapeutic potential of microparticles with antidiabetic effect: Trends and possible applications. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 111, p. 21-pg., . (15/50333-1)
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