Laccase/TEMPO-mediated glycerol oxidation spectroscopic and electrochemical assess...
| Grant number: | 15/50412-9 |
| Support Opportunities: | Research Grants - Visiting Researcher Grant - International |
| Duration: | July 01, 2016 - August 31, 2016 |
| Field of knowledge: | Biological Sciences - Biochemistry - Chemistry of Macromolecules |
| Convênio/Acordo: | CONFAP ; Newton Fund, with FAPESP as a partner institution in Brazil |
| Principal Investigator: | Marcelo Andrade de Lima |
| Grantee: | Marcelo Andrade de Lima |
| Visiting researcher: | Edwin Alexander Yates |
| Visiting researcher institution: | University of Liverpool, England |
| Host Institution: | Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil |
Abstract
Studying polysaccharide-protein interactions under physiological conditions by conventional techniques is challenging. Ideally, macromolecules could be followed by both in vitro spectroscopy experiments and in tissues using microscopy, to enable a proper comparison of results, 19F labelling of glycosaminoglycan's provides background-free signals with potential in both 19F-Nuclear Magnetic Ressonance (NMR) protein-binding studies and non-linear microscopy. (AU)
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