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Use of drugs containing nanocarriers with photosensitizers and/or other active compounds applied to cell therapy and treatment of central nervous system disorders

Grant number: 13/50181-1
Support Opportunities:Research Projects - Thematic Grants
Duration: June 01, 2015 - March 31, 2021
Field of knowledge:Health Sciences - Pharmacy - Pharmaceutical Technology
Principal Investigator:Antonio Claudio Tedesco
Grantee:Antonio Claudio Tedesco
Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Pesquisadores principais:
Sergio Cavalheiro
Associated grant(s):18/01608-6 - 19th European Symposium on Radiopharmacy and Radiopharmaceuticals, AR.EXT
17/01273-1 - Multi-user equipament approved in grants 13/50181-1:spectrofluorometer model RF-6000 Shmadzu and accessories, AP.EMU
17/04915-4 - Multi-user equipament approved in grants 13/50181-1: Bio-Scaffold printer 3D 3axis com precisão nos eixos XYZ- 3D, AP.EMU
Associated scholarship(s):20/06523-9 - Use of nanocarriers containing photosensitizing drugs and other actives applied to cell therapy of central nervous system pathologies treatment, BP.PD
19/04801-4 - Use of nanocarriers containing photosensitizing drugs and other actives applied to cell therapy and treatment of pathologies of the central nervous system, BP.TT
18/24004-9 - Nanocarriers loaded with photosensitizers and others drugs derived of growth factors applied to Photodynamic Processes in treatment of central nervous system diseases, BP.PD
15/18684-9 - Use of drugs containing nanocarriers with photosensitizers and/or other active compounds applied to cell therapy and treatment of central nervous system disorders, BP.PD
14/11870-9 - Sensitizing cancer cell lines to photodynamic therapy through inhibition of protein APE1, BP.PD

Abstract

The central nervous system (CNS) is composed of astrocytes (50%), oligodendrocytes (40%), microglia (5%) and ependymal cells (5%) which provide structural and functional support to neurons. In particular glial tumors (glioma or, glioblastoma) are among ... (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
Articles published in other media outlets (0 total):
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VEICULO: TITULO (DATA)

Scientific publications (62)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
GUSMAO, LUIZA ARAUJO; MATSUO, FLAVIA SAYURI; BARBOSA, HELLEN FRANCIANE GONCALVES; TEDESCO, ANTONIO CLAUDIO. Advances in nano-based materials for glioblastoma multiforme diagnosis: A mini-review. FRONTIERS IN NANOTECHNOLOGY, v. 4, p. 14-pg., . (13/50181-1, 18/17911-0)
BARBOSA, HELLEN FRANCIANE GONCALVES; PIVA, HENRIQUE LUIS; MATSUO, FLAVIA SAYURI; DE LIMA, SARAH CAROLINE GOMES; DE SOUZA, LUCAS EDUARDO BOTELHO; OSAKO, MARIANA KIOMY; TEDESCO, ANTONIO CLAUDIO. Hybrid lipid-biopolymer nanocarrier as a strategy for GBM photodynamic therapy (PDT). International Journal of Biological Macromolecules, v. 242, p. 14-pg., . (18/17911-0, 13/50181-1, 20/04009-6)
CURYLOFO-ZOTTI, FABIANA ALMEIDA; OLIVEIRA, VIVIANE DE CASSIA; MARCHESIN, ANALU RODRIGUEZ; BORGES, HIAGO SALGE; TEDESCO, ANTONIO CLAUDIO; CORONA, SILMARA APARECIDA MILORI. In vitro antibacterial activity of green tea-loaded chitosan nanoparticles on caries-related microorganisms and dentin after Er:YAG laser caries removal. Lasers in Medical Science, v. 38, n. 1, p. 8-pg., . (13/50181-1, 18/23862-1, 17/11582-1, 17/00720-4, 19/04807-2)
TEDESCO, ANTONIO CLAUDIO; SILVA, EMANOEL P. O.; JAYME, CRISTIANO C.; PIVA, HENRIQUE L.; FRANCHI, LEONARDO P.. Cholesterol-rich nanoemulsion (LDE) as a novel drug delivery system to diagnose, delineate, and treat human glioblastoma. Materials Science & Engineering C-Materials for Biological Applications, v. 123, . (12/25216-3, 18/10237-1, 13/50181-1, 14/11870-9)
JAYME, CRISTIANO CERON; PIRES, ANANDA FERREIRA; FERNANDES, DANIELA SILVESTRINI; BI, HONG; TEDESCO, ANTONIO CLAUDIO. DNA polymer films used as drug delivery systems to early-stage diagnose and treatment of breast cancer using 3D tumor spheroids as a model. Photodiagnosis and Photodynamic Therapy, v. 37, p. 12-pg., . (18/10237-1, 13/50181-1)
PADILHA-NAKAGHI, LUCIANA C.; USCATEGUI, RICARDO A. R.; OLIVEIRA, MARIA EMILIA F.; NOCITI, RICARDO P.; MACENTE, I, BEATRICE; COUTINHO, LEANDRO N.; NAKAGHI, EDUARDO YO; MOTTA, GUILHERME A.; SANTOS, VICTOR J. C.; MACIEL, GIOVANNA S.; et al. Local alpha 1-adrenergic blockers: An alternative for sheep cervix dilation?. Animal Reproduction Science, v. 222, . (13/50181-1)
CALORI, ITALO RODRIGO; BRAGA, GUSTAVO; CARVALHO DE JESUS, PRISCILA DA COSTA; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Polymer scaffolds as drug delivery systems. EUROPEAN POLYMER JOURNAL, v. 129, . (13/50181-1)
DE MELO, MARYANNE TRAFANI; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO. Design of new protein drug delivery system (PDDS) with photoactive compounds as a potential application in the treatment of glioblastoma brain cancer. Materials Science & Engineering C-Materials for Biological Applications, v. 110, . (13/50181-1)
SOUZA, CARLA; JAYME, CRISTIANO CERON; REZENDE, NAYARA; TEDESCO, ANTONIO CLAUDIO. Synergistic effect of photobiomodulation and phthalocyanine photosensitizer on fibroblast signaling responses in an in vitro three-dimensional microenvironment. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 222, . (13/50181-1, 18/10237-1, 17/01272-5)
REZENDE, NAYARA; JAYME, CRISTIANO CERON; BRASSESCO, MARIA SOL; TEDESCO, ANTONIO CLAUDIO; DE OLIVEIRA, HARLEY FRANCISCO. Standardization of a resazurin-based assay for the evaluation of metabolic activity in oral squamous carcinoma and glioblastoma cells. Photodiagnosis and Photodynamic Therapy, v. 26, p. 371-374, . (18/10237-1, 13/50181-1, 14/09421-1)
CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Aluminum chloride phthalocyanine in MCF-7: Rationally accounting for state of aggregation of photosensitizers inside cells. DYES AND PIGMENTS, v. 173, . (13/50181-1)
CALORI, ITALO RODRIGO; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO. Targeted cancer therapy using alpha-cyano-4-hydroxycinnamic acid as a novel vector molecule: A proof-of-concept study. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, v. 57, . (13/50181-1)
SIMIONI, ANDREZA RIBEIRO; CARVALHO DE JESUS, PRISCILA COSTA; TEDESCO, ANTONIO CLAUDIO. Layer-by-layer hollow photosensitizer microcapsule design via a manganese carbonate hard template for photodynamic therapy in cells. Photodiagnosis and Photodynamic Therapy, v. 22, p. 169-177, . (13/50181-1)
PELLOSI, DIOGO SILVA; CARVALHO DE JESUS, PRISCILA DA COSTA; TEDESCO, ANTONIO CLAUDIO. Spotlight on the delivery of photosensitizers: different approaches for photodynamic-based therapies. Expert Opinion on Drug Delivery, v. 14, n. 12, p. 1395-1406, . (13/50181-1)
JAYME, CRISTIANO CERON; CALORI, ITALO RODRIGO; FREIRE CUNHA, ELISE MARQUES; TEDESCO, ANTONIO CLAUDIO. Evaluation of aluminum phthalocyanine chloride and DNA interactions for the design of an advanced drug delivery system in photodynamic therapy. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 201, p. 242-248, . (13/50181-1)
CABRAL, AGATA SILVA; RIVAS LEONEL, ELLEN CRISTINA; CANDIDO, NATALIA MARIA; PIVA, HENRIQUE LUIS; DE MELO, MARYANNE TRAFANI; TABOGA, SEBASTIAO ROBERTO; RAHAL, PAULA; TEDESCO, ANTONIO CLAUDIO; CALMON, MARILIA FREITAS. Combined photodynamic therapy with chloroaluminum phthalocyanine and doxorubicin nanoemulsions in breast cancer model. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 218, . (20/04009-6, 13/50181-1)
SOBRAL, V, DANIELLE; FUSCALDI, LEONARDO L.; DURANTE, ANA CLAUDIA R.; RANGEL, MAYARA G.; OLIVEIRA, LARISSA R.; MENDONCA, FERNANDA F.; MIRANDA, ANA CLAUDIA C.; CABEZA, JORGE M.; MONTOR, WAGNER R.; CABRAL, FRANCISCO R.; et al. Radiochemical and biological properties of peptides designed to interact with EGF receptor: Relevance for glioblastoma. NUCLEAR MEDICINE AND BIOLOGY, v. 88-89, p. 14-23, . (13/50181-1)
VENDETTE, ANTONIO CARLOS FIGUEIREDO; PIVA, HENRIQUE LUIS; MUEHLMANN, LUIS ALEXANDRE; DE SOUZA, DELFRANK ANANIAS; TEDESCO, ANTONIO CLAUDIO; AZEVEDO, RICARDO BENTES. Clinical treatment of intra-epithelia cervical neoplasia with photodynamic therapy. INTERNATIONAL JOURNAL OF HYPERTHERMIA, v. 37, n. 3, p. 9-pg., . (13/50181-1)
DAVANZO, NATHALIA NOSSI; PELLOSI, DIOGO SILVA; FRANCHI, LEONARDO PEREIRA; TEDESCO, ANTONIO CLAUDIO. Light source is critical to induce glioblastoma cell death by photodynamic therapy using chloro-aluminiumphtalocyanine albumin-based nanoparticles. Photodiagnosis and Photodynamic Therapy, v. 19, p. 181-183, . (16/00389-3, 13/50181-1, 14/11870-9)
GOTO, PATRICIA L.; SIQUEIRA-MOURA, MARIGILSON P.; TEDESCO, ANTONIO C.. Application of aluminum chloride phthalocyanine-loaded solid lipid nanoparticles for photodynamic inactivation of melanoma cells. International Journal of Pharmaceutics, v. 518, n. 1-2, p. 228-241, . (13/50181-1)
PELLOSI, DIOGO SILVA; CALORI, ITALO RODRIGO; DE PAULA, LEONARDO BARCELOS; HIOKA, NOBORU; QUAGLIA, FABIANA; TEDESCO, ANTONIO CLAUDIO. Multifunctional theranostic Pluronic mixed micelles improve targeted photoactivity of Verteporfin in cancer cells. Materials Science & Engineering C-Materials for Biological Applications, v. 71, p. 1-9, . (13/50181-1, 16/00389-3, 15/18684-9)
CALORI, ITALO RODRIGO; JAYME, CRISTIANO CERON; UENO, LEONARDO TSUYOSHI; CORRETO MACHADO, FRANCISCO BOLIVAR; TEDESCO, ANTONIO CLAUDIO. Theoretical and experimental studies concerning monomer/aggregates equilibrium of zinc phthalocyanine for future photodynamic action. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 214, p. 513-521, . (18/10237-1, 13/50181-1)
OLIVEIRA, P. M.; LOPES, T. Z.; TEDESCO, A. C.; RAHAL, P.; CALMON, M. F.. Effect of berberine associated with photodynamic therapy in cell lines. Photodiagnosis and Photodynamic Therapy, v. 32, . (13/50181-1, 15/16660-5)
BORGES, HIAGO SALGE; GUSMAO, LUIZA ARAUJO; TEDESCO, ANTONIO CLAUDIO. Multi-charged nanoemulsion for photodynamic treatment of glioblastoma cell line in 2D and 3D in vitro models. Photodiagnosis and Photodynamic Therapy, v. 43, p. 12-pg., . (13/50181-1)
MONICO, DANIELLI AZEVEDO; CALORI, ITALO RODRIGO; SOUZA, CARLA; ESPREAFICO, ENILZA MARIA; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Melanoma spheroid-containing artificial dermis as an alternative approach to in vivo models. Experimental Cell Research, v. 417, n. 1, p. 11-pg., . (20/04507-6, 13/50181-1, 17/01272-5)
MONGE-FUENTES, VICTORIA; MAYER, ANDREIA BIOLCHI; LIMA, MARCOS ROBALINHO; GERALDES, LUIZA RIBEIRO; ZANOTTO, LARISSA NEPOMUCENO; MOREIRA, KARLA GRAZIELLA; MARTINS, OLIMPIA PASCHOAL; PIVA, HENRIQUE LUIS; SOARES FELIPE, MARIA SUELI; AMARAL, ANDRE CORREA; et al. Dopamine-loaded nanoparticle systems circumvent the blood-brain barrier restoring motor function in mouse model for Parkinson's Disease. SCIENTIFIC REPORTS, v. 11, n. 1, . (13/50181-1)
FRANCHI, LEONARDO PEREIRA; BARBOSA DE FREITAS LIMA, JESSICA ELLEN; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO. The redox function of apurinic/apyrimidinic endonuclease 1 as key modulator in photodynamic therapy. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 211, p. 13-pg., . (17/14630-7, 13/50181-1, 14/11870-9)
JAYME, CRISTIANO CERON; CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Spectroscopic analysis of aluminum chloride phthalocyanine in binary water/ethanol systems for the design of a new drug delivery system for photodynamic therapy cancer treatment. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 153, p. 178-183, . (13/50181-1)
CASTILHO-FERNANDES, ANDRIELLE; LOPES, TACILA G.; PRIMO, FERNANDO L.; PINTO, MARCELO R.; TEDESCO, ANTONIO C.. Photodynamic process induced by chloro-aluminum phthalocyanine nanoemulsion in glioblastoma. Photodiagnosis and Photodynamic Therapy, v. 19, p. 221-228, . (13/50181-1, 16/21504-5)
SILVA, E. P. O.; FRANCHI, L. P.; TEDESCO, A. C.. Chloro-aluminium phthalocyanine loaded in ultradeformable liposomes for photobiology studies on human glioblastoma. RSC ADVANCES, v. 6, n. 83, p. 79631-79640, . (12/25216-3, 13/50181-1, 14/11870-9)
VENDETTE, ANTONIO CARLOS FIGUEIREDO; PIVA, HENRIQUE LUIS; MUEHLMANN, LUIS ALEXANDRE; DE SOUZA, DELFRANK ANANIAS; TEDESCO, ANTONIO CLAUDIO; AZEVEDO, RICARDO BENTES. Clinical treatment of intra-epithelia cervical neoplasia with photodynamic therapy. INTERNATIONAL JOURNAL OF HYPERTHERMIA, v. 37, n. 3, SI, p. 50-58, . (13/50181-1)
CALORI, ITALO RODRIGO; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Expanding the Limits of Photodynamic Therapy: The Design of Organelles and Hypoxia-Targeting Nanomaterials for Enhanced Photokilling of Cancer. ACS APPLIED BIO MATERIALS, v. 4, n. 1, p. 195-228, . (20/06523-9, 13/50181-1)
ALVES, SAMARA RODRIGUES; CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Photosensitizer-based metal-organic frameworks for highly effective photodynamic therapy. Materials Science & Engineering C-Materials for Biological Applications, v. 131, . (20/04507-6, 13/50181-1)
RIBEIRO CAVALCANTE, LEONARDO LOBO; TEDESCO, ANTONIO CLAUDIO; SOUZA-GABRIEL, ALINE EVANGELISTA; BORGES, HIAGO SALGE; CURYLOFO-ZOTTI, FABIANA ALMEIDA; MILORI CORONA, SILMARA APARECIDA. Photoinactivation of multispecies cariogenic biofilm mediated by aluminum phthalocyanine chloride encapsulated in chitosan nanoparticles. Lasers in Medical Science, . (13/50181-1, 19/05965-0)
CALORI, ITALO RODRIGO; PINHEIRO, LUKAS; BRAGA, GUSTAVO; PEDROSO DE MORAIS, FLAVIA AMANDA; CAETANO, WILKER; TEDESCO, ANTONIO CLAUDIO; HIOKA, NOBORU. Interaction of triblock copolymers (Pluronic (R)) with DMPC vesicles: a photophysical and computational study. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 275, p. 10-pg., . (20/04507-6, 13/50181-1)
SOUZA, CARLA; MONICO, DANIELLI AZEVEDO; TEDESCO, ANTONIO CLAUDIO. Implications of dichlorofluorescein photoinstability for detection of UVA-induced oxidative stress in fibroblasts and keratinocyte cells. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, v. 19, n. 1, p. 40-48, . (13/50181-1, 17/01272-5)
SOUZA, CARLA; PELLOSI, DIOGO SILVA; TEDESCO, ANTONIO CLAUDIO. Prodrugs for targeted cancer therapy. EXPERT REVIEW OF ANTICANCER THERAPY, v. 19, n. 6, p. 483-502, . (16/00389-3, 13/50181-1, 17/01272-5)
CALORI, ITALO RODRIGO; ALVES, SAMARA RODRIGUES; BI, HONG; TEDESCO, ANTONIO CLAUDIO. Type-I Collagen/Collagenase Modulates the 3D Structure and Behavior of Glioblastoma Spheroid Models. ACS APPLIED BIO MATERIALS, v. 5, n. 2, p. 11-pg., . (20/04507-6, 13/50181-1)
JAYME, CRISTIANO CERON; SOUZA, CARLA; FERNANDES, DANIELA SILVESTRINI; TEDESCO, ANTONIO CLAUDIO. Tailoring the growth and proliferation of human dermal fibroblasts by DNA-based polymer films for skin regeneration. Journal of Biomedical Materials Research Part A, v. 109, n. 11, p. 2381-2391, . (17/01272-5, 18/10237-1, 13/50181-1)
DA SILVA, DARLAN BARBOSA; DA SILVA, CAROLINA LOUREIRO; DAVANZO, NATHALIA NOSSI; SOUZA, RODRIGO DA SILVA; CORREA, RODRIGO JOSE; TEDESCO, ANTONIO CLAUDIO; RIEMMA PIERRE, MARIA BERNADETE. Protoporphyrin IX (PpIX) loaded PLGA nanoparticles for topical Photodynamic Therapy of melanoma cells. Photodiagnosis and Photodynamic Therapy, v. 35, . (13/50181-1, 15/16660-5)
GALIARDI-CAMPOY, ANA EMILIA BRUMATTI; MACHADO, FRANCIELLY CRISTINA; CARVALHO, TAMARA; TEDESCO, ANTONIO CLAUDIO; RAHAL, PAULA; CALMON, MARILIA FREITAS. Effects of photodynamic therapy mediated by emodin in cervical carcinoma cells. Photodiagnosis and Photodynamic Therapy, v. 35, . (13/50181-1, 15/16660-5)
SALLES DE OLIVEIRA, DAPHNE CHRISTINE; DE FREITAS, CAMILA FABIANO; CALORI, ITALO RODRIGO; GONCALVES, RENATO SONCHINI; ERRERIAS FERNANDES CARDINALI, CAMILA APARECIDA; MALACARNE, LUIS CARLOS; RAVANELLI, MARIA IDA; DE OLIVEIRA, HUEDER PAULO MOISES; TEDESCO, ANTONIO CLAUDIO; CAETANO, WILKER; et al. Theranostic verteporfin- loaded lipid-polymer liposome for photodynamic applications. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 212, . (13/50181-1)
FERREIRA PIRES, ANANDA. Development of DNA polymer films as a drug delivery system for the treatment of oral cancer. DRUG DELIVERY AND TRANSLATIONAL RESEARCH, v. 10, n. 6, SI, . (13/50181-1, 18/10237-1)
PELLOSI, DIOGO S.; PAULA, LEONARDO B.; DE MELO, MARYANNE T.; TEDESCO, ANTONIO C.. Targeted and Synergic Glioblastoma Treatment: Multifunctional Nanoparticles Delivering Verteporfin as Adjuvant Therapy for Temozolomide Chemotherapy. MOLECULAR PHARMACEUTICS, v. 16, n. 3, p. 1009-1024, . (13/50181-1, 16/00389-3, 18/24004-9, 15/18684-9)
SIMAO, DANIELE O.; HONORATO, THALITA D.; GOBO, GRACIELY G.; PIVA, HENRIQUE L.; GOTO, PATRICIA L.; ROLIM, LARISSA A.; TURRIN, CEDRIC-OLIVIER; BLANZAT, MURIEL; TEDESCO, ANTONIO C.; SIQUEIRA-MOURA, MARIGILSON P.. Preparation and cytotoxicity of lipid nanocarriers containing a hydrophobic flavanone. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, v. 601, . (13/50181-1)
DE ANDRADE, LAISE R.; TEDESCO, ANTONIO C.; PRIMO, FERNANDO L.; FARIAS, GABRIEL R.; DA SILVA, JAQUELINE R.; LONGO, JOAO P. F.; DE ALMEIDA, MARCOS C.; DE SOUZA, PAULO E. N.; DE AZEVEDO, RICARDO B.; PINHEIRO, WILLIE O.; et al. Tumor cell death in orthotopic breast cancer model by NanoALA: a novel perspective on photodynamic therapy in oncology. Nanomedicine, v. 15, n. 10, p. 1019-1036, . (13/50181-1)
UNTEN TAKAHASHI, LUANDRA APARECIDA; MILORI CORONA, SILMARA APARECIDA. Conjugate of chitosan nanoparticles with chloroaluminium phthalocyanine: Synthesis, characterization and photoinactivation of Streptococcus mutans biofilm. Photodiagnosis and Photodynamic Therapy, v. 30, . (13/50181-1, 19/05965-0)
PELLOSI, DIOGO SILVA; MACAROFF, PATRICIA PEREIRA; MORAIS, PAULO CESAR; TEDESCO, ANTONIO CLAUDIO. Magneto low-density nanoemulsion (MLDE): A potential vehicle for combined hyperthermia and photodynamic therapy to treat cancer selectively. Materials Science & Engineering C-Materials for Biological Applications, v. 92, p. 103-111, . (15/18684-9, 16/00389-3, 13/50181-1)
CASTILHO-FERNANDES, ANDRIELLE; LOPES, TADLA G.; FERREIRA, FERNANDO U.; REZENDE, NAYARA; SILVA, VALERIA F.; PRIMO, FERNANDO L.; FONTES, APARECIDA MARIA; RIBEIRO-SILVA, ALFREDO; TEDESCO, ANTONIO CLAUDIO. Adipogenic differentiation of murine bone marrow mesenchymal stem cells induced by visible light via photo- induced biomodulation. Photodiagnosis and Photodynamic Therapy, v. 25, p. 119-127, . (13/50181-1)
CERON JAYME, CRISTIANO; FERREIRA PIRES, ANANDA; TEDESCO, ANTONIO CLAUDIO. Development of DNA polymer films as a drug delivery system for the treatment of oral cancer. DRUG DELIVERY AND TRANSLATIONAL RESEARCH, v. 10, n. 6, p. 14-pg., . (18/10237-1, 13/50181-1)
FERREIRA-SILVA, VALERIA; PRIMO, FERNANDO L.; BAQUI, MUNIRA M. A.; MAGALHAES, DANIELLE A. R.; ORELLANA, MARISTELA D.; CASTILHO-FERNANDES, ANDRIELLE; CRUZ, MARIO C.; CAMARA, NIEHLS O. S.; COVAS, DIMAS T.; TEDESCO, ANTONIO C.. Beneficial Role of Low-Intensity Laser Irradiation on Neural beta-tubulin III Protein Expression in Human Bone Marrow Multipotent Mesenchymal Stromal Cells. STEM CELL REVIEWS AND REPORTS, v. 14, n. 4, p. 585-598, . (13/50181-1)
JAYME, CRISTIANO CERON; DE PAULA, LEONARDO BARCELOS; REZENDE, NAYARA; CALORI, ITALO RODRIGO; FRANCHI, LEONARDO PEREIRA; TEDESCO, ANTONIO CLAUDIO. DNA polymeric films as a support for cell growth as a new material for regenerative medicine: Compatibility and applicability. Experimental Cell Research, v. 360, n. 2, p. 404-412, . (15/18684-9, 13/50181-1, 14/11870-9)
FERREIRA-SILVA, VALERIA; PRIMO, FERNANDO L.; BAQUI, MUNIRA M. A.; MAGALHAES, DANIELLE A. R.; ORELLANA, MARISTELA D.; CASTILHO-FERNANDES, ANDRIELLE; CRUZ, MARIO C.; CAMARA, NIEHLS O. S.; COVAS, DIMAS T.; TEDESCO, ANTONIO C.. Beneficial Role of Low-Intensity Laser Irradiation on Neural beta-tubulin III Protein Expression in Human Bone Marrow Multipotent Mesenchymal Stromal Cells. STEM CELL REVIEWS AND REPORTS, v. 14, n. 4, p. 14-pg., . (13/50181-1)
FLORIANO, BARBARA FREITAS; CARVALHO, TAMARA; LOPES, TAIRINE ZARA; UNTEN TAKAHASHI, LUANDRA APARECIDA; RAHAL, PAULA; TEDESCO, ANTONIO CLAUDIO; CALMON, MARILIA FREITAS. Effect of berberine nanoemulsion Photodynamic therapy on cervical carcinoma cell line. Photodiagnosis and Photodynamic Therapy, v. 33, . (15/16660-5, 13/50181-1)
GOBO, GRACIELY GOMIDES; PIVA, HENRIQUE LUIS; TEDESCO, ANTONIO CLAUDIO; PRIMO, FERNANDO LUCAS. Novel quinizarin spray-dried nanoparticles for treating melanoma with photodynamic therapy. MATERIALS TODAY COMMUNICATIONS, v. 33, p. 9-pg., . (13/50181-1, 20/04009-6)
CALORI, ITALO RODRIGO; BRAGA, GUSTAVO; TESSARO, ANDRE LUIZ; CAETANO, WILKER; TEDESCO, ANTONIO CLAUDIO; HIOKA, NOBORU. Self-aggregation of the proteolytic forms of Verteporfin: An in silico and in vitro study. JOURNAL OF MOLECULAR LIQUIDS, v. 352, p. 9-pg., . (20/04507-6, 13/50181-1)
JAYME, CRISTIANO CERON; REZENDE, NAYARA; FERNANDES, DANIELA S. .; PAULA, LEONARDO B. DE; DE CASTRO, BARBARA GIMENES; TAKAHASHI, LUANDRA APARECIDA U. .; TEDESCO, ANTONIO CLAUDIO. Target selectivity of cholesterol-phosphatidylcholine liposome loaded with phthalocyanine for breast cancer diagnosis and treatment by photodynamic therapy. Photodiagnosis and Photodynamic Therapy, v. 39, p. 6-pg., . (18/24004-9, 21/02207-8, 18/10237-1, 15/18684-9, 13/50181-1)
FRANCHI, LEONARDO PEREIRA; AMANTINO, CAMILA F.; MELO, MARYANNE T.; DE LIMA MONTALDI, ANA PAULA; PRIMO, FERNANDO L.; TEDESCO, ANTONIO CLAUDIO. In vitro effects of photodynamic therapy induced by chloroaluminum phthalocyanine nanoemulsion. Photodiagnosis and Photodynamic Therapy, v. 16, p. 100-105, . (13/50181-1, 14/11870-9)
LEANDRO, FERNANDA Z.; MARTINS, JULIA; FONTES, APARECIDA M.; TEDESCO, ANTONIO C.. Evaluation of theranostic nanocarriers for near-infrared imaging and photodynamic therapy on human prostate cancer cells. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 154, p. 341-349, . (13/50181-1, 08/53719-4)
CALORI, ITALO RODRIGO; TEDESCO, ANTONIO CLAUDIO. Lipid vesicles loading aluminum phthalocyanine chloride: Formulation properties and disaggregation upon intracellular delivery. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 160, p. 240-247, . (13/50181-1)
DE PAULA, L. B.; PRIMO, F. L.; PINTO, M. R.; MORAIS, P. C.; TEDESCO, A. C.. Evaluation of a chloroaluminium phthalocyanine-loaded magnetic nanoemulsion as a drug delivery device to treat glioblastoma using hyperthermia and photodynamic therapy. RSC ADVANCES, v. 7, n. 15, p. 9115-9122, . (15/18684-9, 13/50181-1)
CURYLOFO-ZOTTI, FABIANA ALMEIDA; TEDESCO, ANTONIO CLAUDIO; LIZARELLI, GUSTAVO TEODORO COSTA; TAKAHASHI, LUANDRA APARECIDA UNTEN; CORONA, SILMARA APARECIDA MILORI. Effect of green tea-loaded chitosan nanoparticles on leathery dentin microhardness. ODONTOLOGY, v. 109, n. 4, p. 8-pg., . (17/11582-1, 13/50181-1, 19/04807-2)

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