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Cities and mental health: examining social determinants of mental disorders in large urban areas in a multicentric analysis of the World Mental Health Survey Initiative


Mental disorders have been growing in importance and are now one of the leading causes of morbidity and incapacity, especially in large urban areas. This project aims to identify and analyze the social determinants of mental disorders in the ten megacities (cities with more than 10 million inhabitants) of the World Mental Health Survey Initiative (WMHSI): New York City, Los Angeles, Shanghai, Beijing, Shenzhen, Lagos, Mexico City, Paris, Buenos Aires and São Paulo, totaling around 20,000 individuals (an average of 2,000 per megacity), representing a reasonably well-distributed sample from low (Nigeria and China), medium (Brazil, Argentina and Mexico) and high (United States and France) income countries. The dependent variables of interest are major depression, anxiety and any mental disorders, identified using the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria, translated and adapted for each language. The first part of the analysis will use Bayesian logistic multilevel models to test the association of the three dependent variables with the individual (sex, age, education, individual income and marital status) and contextual (income inequality, median income and violence) determinants. We will then use structural equation models to test for the presence of a mediating effect of different aspects of the individual's social networks in the association between the contextual determinants and mental disorders. This study will be a collaboration between the School of Public Health of the University of São Paulo, the Psychiatric Institute of the University of São Paulo, the Mailman School of Public Health of Columbia University and the Harvard Medical School. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ASKARI, MELANIE S.; ANDRADE, LAURA HELENA; FILHO, ALEXANDRE CHIAVEGATTO; SILVEIRA, CAMILA MAGALHAES; SIU, ERICA; WANG, YUAN-PANG; VIANA, MARIA CARMEN; MARTINS, SILVIA S.. Dual burden of chronic physical diseases and anxiety/mood disorders among Sao Paulo Megacity Mental Health Survey Sample, Brazil. Journal of Affective Disorders, v. 220, p. 1-7, . (11/50517-4, 14/05363-7, 03/00204-3)
PORTO CHIAVEGATTO FILHO, ALEXANDRE DIAS; WANG, YUAN-PANG; COELHO CAMPINO, ANTONIO CARLOS; MALIK, ANA MARIA; VIANA, MARIA CARMEN; ANDRADE, LAURA HELENA. Incremental health expenditure and lost days of normal activity for individuals with mental disorders: results from the Sao Paulo Megacity Study. BMC PUBLIC HEALTH, v. 15, . (14/05363-7, 03/00204-3)
PORTO CHIAVEGATTO FILHO, ALEXANDRE DIAS; SAMPSON, LAURA; MARTINS, SILVIA S.; YU, SHUI; HUANG, YUEQIN; HE, YANLING; LEE, SING; HU, CHIYI; ZASLAVSKY, ALAN; KESSLER, RONALD C.; et al. Neighbourhood characteristics and mental disorders in three Chinese cities: multilevel models from the World Mental Health Surveys. BMJ OPEN, v. 7, n. 10, . (14/05363-7)

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