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Surveillance and diagnosis of HTLV-1 and HTLV-2 in HIV-infected individuals (SuDiHIV/HTLV)

Abstract

The aim of the present study is: (i) Establish a surveillance and diagnostic multidisciplinary group of HTLV-1 and HTLV-2 infections at IAL (SuDiHIV/HTLV), firstly analyzing samples from HlV-infected patients attended at the STD/AIDS Reference Center in São Paulo, Brazil (CRT DST/Aids); (ii) compare the efficiency of HTLV-1/2 confirmatory assays in the diagnosis of HIV/HTLV-1/2 coinfected individuals (iii) detect HTLV-1/2 proviral load during ARV therapy, (iv) characterize HTLV and HIV isolates, including HIV tropism, (v) search for unique insertion sites (UIS) and clonallity in HTLV-1/H1V coinfected individuals (in London); (vi) evaluate the number and function of T regulatory cells, and (vii) using bioinformatics and statistical tools, correlate the results obtained with socio-demographic and clinical data. (AU)

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Scientific publications (12)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FABIANA APARECIDA ALVES; KAROLINE RODRIGUES CAMPOS; MARCÍLIO FIGUEIREDO LEMOS; REGINA CÉLIA MOREIRA; ADELE CATERINO-DE-ARAUJO. Hepatitis C viral load in HCV-monoinfected and HCV/HIV-1-, HCV/HTLV-1/-2-, and HCV/HIV/HTLV-1/-2-co-infected patients from São Paulo, Brazil. Brazilian Journal of Infectious Diseases, v. 22, n. 2, p. 123-128, . (16/03654-0, 12/51220-8)
CATERINO-DE-ARAUJO, ADELE; CAMPOS, KAROLINE R.; OLIVEIRA, LUANDA M. S.; RIGATO, PAULA O.. Biomarkers in a Cohort of HIV-Infected Patients Single- or Co-Infected with HTLV-1, HTLV-2, and/or HCV: A Cross-Sectional, Observational Study. Viruses-Basel, v. 14, n. 9, p. 13-pg., . (16/03654-0, 12/51220-8)
KAROLINE RODRIGUES CAMPOS; MARIA GISELE GONÇALVES; NADIA APARECIDA COSTA; ADELE CATERINO-DE-ARAUJO. Comparative performances of serologic and molecular assays for detecting human T lymphotropic virus type 1 and type 2 (HTLV-1 and HTLV-2) in patients infected with human immunodeficiency virus type 1 (HIV-1). Brazilian Journal of Infectious Diseases, v. 21, n. 3, p. 297-305, . (13/19775-2, 16/03654-0, 12/51220-8)
CAMPOS, KAROLINE RODRIGUES; GONCALVES, MARIA GISELE; CATERINO-DE-ARAUJO, ADELE. Short Communication: Failures in Detecting HTLV-1 and HTLV-2 in Patients Infected with HIV-1. AIDS Research and Human Retroviruses, v. 33, n. 4, p. 382-385, . (12/51220-8, 16/03654-0)
CATERINO-DE-ARAUJO, ADELE; ALVES, FABIANA APARECIDA; CAMPOS, KAROLINE RODRIGUES; LEMOS, MARCILIO FIGUEIREDO; MOREIRA, REGINA CELIA. Making the invisible visible: searching for human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) in Brazilian patients with viral hepatitis B and C. Memórias do Instituto Oswaldo Cruz, v. 113, n. 2, p. 5-pg., . (12/51220-8)
CAMPOS, KAROLINE R.; SANTOS, FRED L. N.; BRITO, VANESSA DA SILVA; GONCALVES, NOILSON L. S.; ARAUJO, THESSIKA H. A.; GALVAO-CASTRO, BERNARDO; CATERINO-DE-ARAUJO, ADELE. Line Immunoassay for Confirmation and Discrimination of Human T-Cell Lymphotropic Virus Infections in Inconclusive Western Blot Serum Samples from Brazil. Journal of Clinical Microbiology, v. 58, n. 1, . (16/03654-0, 12/51220-8)
ALVES, FABIANA APARECIDA; CAMPOS, KAROLINE RODRIGUES; LEMOS, MARCILIO FIGUEIREDO; MOREIRA, REGINA CELIA; CATERINO-DE-ARAUJO, ADELE. Hepatitis C viral load in HCV-monoinfected and HCV/HIV-1-, HCV/HTLV-1/-2-, and HCV/HIV/HTLV-1/-2-co-infected patients from Sao Paulo, Brazil. Brazilian Journal of Infectious Diseases, v. 22, n. 2, p. 123-128, . (16/03654-0, 12/51220-8)
CATERINO-DE-ARAUJO, ADELE; SACCHI, CLAUDIO TAVARES; GONCALVES, MARIA GISELE; CAMPOS, KAROLINE RODRIGUES; MAGRI, MARIANA CAVALHEIRO; ALENCAR, WONG KUEN; SAO, GRP SURVEILLANCE DIAG HTLV. Short Communication: Current Prevalence and Risk Factors Associated with Human T Lymphotropic Virus Type 1 and Human T Lymphotropic Virus Type 2 Infections Among HIV/AIDS Patients in Sao Paulo, Brazil. AIDS Research and Human Retroviruses, v. 31, n. 5, p. 543-549, . (13/19775-2, 12/51220-8)
CATERINO-DE-ARAUJO, ADELE; ALVES, FABIANA APARECIDA; CAMPOS, KAROLINE RODRIGUES; LEMOS, MARCILIO FIGUEIREDO; MOREIRA, REGINA CELIA. Making the invisible visible: searching for human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) in Brazilian patients with viral hepatitis B and C. Memórias do Instituto Oswaldo Cruz, v. 113, n. 2, p. 130-134, . (12/51220-8)
ALVES, FABIANA APARECIDA; CAMPOS, KAROLINE RODRIGUES; LEMOS, MARCILIO FIGUEIREDO; MOREIRA, REGINA CELIA; CATERINO-DE-ARAUJO, ADELE. Hepatitis C viral load in HCV-monoinfected and HCV/HIV-1-, HCV/HTLV-1/-2-, and HCV/HIV/HTLV-1/-2-co-infected patients from Sao Paulo, Brazil. Brazilian Journal of Infectious Diseases, v. 22, n. 2, p. 6-pg., . (16/03654-0, 12/51220-8)
CAMPOS, KAROLINE RODRIGUES; GONCALVES, MARIA GISELE; CATERINO-DE-ARAUJO, ADELE. Short Communication: Failures in Detecting HTLV-1 and HTLV-2 in Patients Infected with HIV-1. AIDS Research and Human Retroviruses, v. 33, n. 4, p. 4-pg., . (16/03654-0, 12/51220-8)
CATERINO-DE-ARAUJO, ADELE; SACCHI, CLAUDIO TAVARES; GONCALVES, MARIA GISELE; CAMPOS, KAROLINE RODRIGUES; MAGRI, MARIANA CAVALHEIRO; ALENCAR, WONG KUEN; GRP SURVEILLANCE DIAG HTLV SAO. Short Communication: Current Prevalence and Risk Factors Associated with Human T Lymphotropic Virus Type 1 and Human T Lymphotropic Virus Type 2 Infections Among HIV/AIDS Patients in Sao Paulo, Brazil. AIDS Research and Human Retroviruses, v. 31, n. 5, p. 7-pg., . (13/19775-2, 12/51220-8)

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