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OCRC - Obesity and Comorbidities Research Center

Grant number: 13/07607-8
Support Opportunities:Research Grants - Research, Innovation and Dissemination Centers - RIDC
Duration: June 01, 2013 - May 31, 2025
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:Licio Augusto Velloso
Grantee:Licio Augusto Velloso
Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Pesquisadores principais:
( Atuais )
Andrei Carvalho Sposito ; Bruno Geloneze Neto ; Carlos Eduardo Negrão ; Everardo Magalhães Carneiro ; Heitor Moreno Junior ; Helena Coutinho Franco de Oliveira ; Jose Antonio Rocha Gontijo ; Jose Donato Junior ; Marcio Alberto Torsoni ; Ronaldo Aloise Pilli ; Silvana Auxiliadora Bordin da Silva ; Wilson Nadruz Junior
Pesquisadores principais:
( Anteriores )
Aníbal Eugênio Vercesi ; Antonio Carlos Boschiero ; Heraldo Possolo de Souza ; José Barreto Campello Carvalheira ; Marcelo Alves da Silva Mori ; Mario Jose Abdalla Saad
Associated researchers:Adriana Souza Torsoni ; Alessandro dos Santos Farias ; Amilton dos Santos Junior ; Ana Carolina Junqueira Vasques ; Ana Paula Couto Davel ; Antonio Carlos Boschiero ; Camilo de Lellis Santos ; Carlos Henrique Grossi Sponton ; Celso Darío Ramos ; Claudio Cesar Zoppi ; Daniel Martins-de-Souza ; Dennys Esper Corrêa Cintra ; Eduardo Rochete Ropelle ; Eliana Pereira de Araujo ; Elinton Adami Chaim ; Erika Anne de Freitas Robles Roman ; Fernando Cendes ; Gabriel Forato Anhê ; Helena Cristina de Lima Barbosa ; Ivani Credidio Trombetta ; João Vilhete Viegas d'Abreu ; José Roberto Matos Souza ; José Rodrigo Pauli ; Joseane Morari Ricciardi de Aguiar ; Kelly Lima Calisto da Silva ; Leonardo dos Reis Silveira ; Letícia Ignácio de Souza Zimmermann ; Lígia de Moraes Antunes Corrêa ; Luiz Osório Silveira Leiria ; Marciane Milanski Ferreira ; Marcio Alberto Torsoni ; Marco Aurélio Ramirez Vinolo ; Maria Helena de Melo Lima ; Maria Luiza Moretti ; Otávio Rizzi Coelho-Filho ; Patrícia Aline Boer ; Patrícia de Oliveira Prada ; Paulo Dalgalarrondo ; Pedro Manoel Mendes de Moraes Vieira ; Raquel Franco Leal ; Renata Frazão ; Roberto Schreiber ; Rodrigo Ramos Catharino ; Roger Frigério Castilho ; Ronaldo Aloise Pilli ; Vera Regina Toledo Camargo
Associated grant(s):23/01442-9 - Evaluation of the phenotype of mice with NHLH2 deletion in POMC neurons, AP.R
22/02840-5 - Influence of airway allergic inflammation on platelet infiltration in the lungs of mice consuming hyperlipidic diet or sucrose consumption: possible participation of gut microbiota, AV.EXT
20/05430-7 - Multicenter, prospective, randomized, double-blind, placebo-controlled study to evaluate the Effect of Diacerein to prevent death or multiple organ dysfunction in patients with ARDS secondary to COVID-19, AP.R
+ associated grants 20/04522-5 - Clinical trial for bradykinin inhibition in hospitalized adults with COVID-19 grave, AP.R
18/25050-4 - EMU granted in the proceeding 2013/07607-8: radiopharmaceutical synthesizer for PET/CT, AP.EMU
18/14132-0 - EANM'18 - Annual Congress of the European AssociaBon of Nuclear Medicine, AR.EXT
15/13362-3 - 9th World Congress of Developmental Origins of Health and Disease, AR.EXT - associated grants
Associated scholarship(s):23/17763-9 - EVALUATION OF THE EFFECTS OF INTERESTERIFIED FAT ON ENERGY HOMEOSTASIS AND INSULIN SIGNALING IN THE HYPOTHALAMUS OF MICE, BP.IC
24/01619-9 - Functional evaluation of nuclear respiration factor-1 (Nrf1) in hypothalamic prooopiomelanocortin neurons, BP.DR
24/01567-9 - The impact of cycles of fat mass gain and loss on systemic metabolism and energy balance in an experimental model of diet-induced obesity, BP.DR
+ associated scholarships 23/13971-6 - Training in research laboratory techniques in endocrine pancreas metabolism., BP.TT
23/14840-2 - EVALUATION OF THE EFFECT OF PHOTOBIOMODULATION ON HIDRADENITIS SUPPURATIVA: PROSPECTIVE STUDY, BP.IC
23/10783-4 - Evaluation of the effect of photobiomodulation on hidradenitis suppurativa: a prospective study., BP.IC
23/11393-5 - Chemokine expression characterization in the hypothalamus of mice fed a high-fat diet for short and long periods, BP.IC
23/07111-4 - Evaluation of the planetary health diet index in the participants of Nutritionist´s Health Study (NutriHS), BP.IC
23/10146-4 - Unveiling the transcription factors related to circadian rhythm regulation in brown adipocytes., BP.IC
23/10154-7 - Unveiling the transcription factors responsible for adipocyte transdifferentiation in humans though in silico analysis., BP.IC
23/07121-0 - Application of body adiposity, body shape, relative fat mass and body roundness indexes in the evaluation of body adiposity and cardiometabolic health in adults., BP.IC
23/07137-3 - EFFECTS OF DAPAGLIFLOZIN ON THE BONE TISSUE OF PATIENTS IN HEMODIALYSIS AND PERITONEAL DIALYSIS, BP.IC
23/01860-5 - Role of peripheral NPY receptors in regulating energy homeostasis, BP.PD
23/07063-0 - Review and systematic analysis of single-cell RNA sequencing in beige and brown adipocytes, BP.IC
23/06913-0 - EFFECTS OF AGE AND OVARIAN FACTORS ON THE EVALUATION OF HYPOTHALAMIC CELLS INVOLVED IN THE REPRODUCTIVE CONTROL OF MICES., BP.IC
23/07030-4 - Growth hormone influence in gonads histology of male and female mice., BP.IC
23/04860-6 - Effects of maternal nutrition in fetal and neonatal periods on monocyte chemotaxis in high-fat diet-induced hypothalamic inflammation in adult life, BP.IC
22/15297-8 - Associations between chronotypes and brown adipose tissue activation in women with different adiposity phenotypes and metabolic health., BP.IC
22/16183-6 - Training in research laboratory techniques in endocrine pancreas metabolism., BP.TT
23/00559-0 - Consequences of gestational stress in kidneys of male mice, BP.IC
22/13145-6 - Unveiling the transcriptional regulation of GPR3 gene in brown adipocytes, BP.PD
22/12938-2 - Evaluation of modulation of hypothalamic BDNF expression under acute high-fat diet exposition, BP.IC
22/12820-1 - Scientific dissemination on social networks of the Obesity and Comorbidities Research Center, BP.TT
21/12441-8 - Long-term modulation of lipoproteins metabolism induced by the use of glucocorticoids during pregnancy, BP.DD
22/09707-9 - EVALUATION OF ENERGY EXPENDITURE AND MODULATION OF PLASTICITY OF ADIPOSE TISSUE INDUCED BY CONSUMPTION OF INTERESTERIFIED OR PARTIALLY HYDROGENATED FAT IN MICE., BP.IC
21/15062-8 - The impact of a high-fat diet on the structure of brown adipose tissue function in three strains of mice - Interface between genetics and nutrition, BP.MS
22/09101-3 - Metabolic phenotyping of mice devoid of neuropeptide Y (NPY) specifically in sympathetic neurons, BP.PD
22/08508-2 - Multi-omic meta-analysis of the immune response to SARS-CoV-2: an integrated approach with cell resolution, BP.DD
22/09841-7 - Evaluation of the main Th2 cytokines in the maintenance of the temperature of newborns and their relationship with atopy, BP.IC
22/08010-4 - Involvement of the alpha-7 nicotinic receptor (±7nAChR) of the hippocampus and prefrontal cortex in the behavioral and plastic responses resulting from the consumption of a high-fat diet, BP.PD
22/08172-4 - Validation of the global diet quality score for the Brazilian population, BP.PD
22/06146-6 - The role of alpha7nAChR signaling in mediating tumor resistance to cancer therapy, BP.PD
21/14364-0 - Complementary technical training, in the area of physiology and molecular biology, in the Laboratory of Cell Signaling., BP.TT
21/06461-6 - Integrated mitochondrial stress response and the regulation of pro-opiomelanocortin processing in hypothalamic neuronal cell lines, BP.MS
21/02008-5 - Brown adipose tissue and associated metabolites in women with different cardiometabolic health phenotypes, BP.DR
22/03416-2 - The effects of high-fat diet consumption on the reproductive behavior and hypothalamic homeostasis in female and male mice, BP.IC
21/13498-3 - Study of resident macrophages from adipose tissue of obese individuals through single-cell RNA sequencing, BP.PD
22/01907-9 - Puberty as an ontogenetic window: the involvement of the autophagy and aging in renal disturbs induced by a high-fat diet, BP.DR
22/00956-6 - Effect of the Enzyme PM20D1 on Metabolism and Thermogenesis in Mice and Humans, BP.DR
21/14184-2 - Training in laboratory techniques of research of the endocrine pancreas metabolism, BP.TT
21/11551-4 - Study of hypothalamic circuits that regulate metabolism and the endocrine system, BP.PD
21/11089-9 - Prevalence and risk factors of subclinical atherosclerotic cardiovascular disease in diabetic patients: results from the Brazilian Diabetes Study, BP.IC
21/11436-0 - Assessment of the influence of glycemic variability on the central retinal thickness as an early marker of diabetic retinopathy: results of the Brazilian Diabetes study, BP.IC
21/10279-9 - Effect of palmitate treatment on the expression of genes involved in the regulation of proopiomelanocortina, BP.IC
21/08370-8 - Intestinal effects of Nicotinamide Riboside and Pterostilbene: an investigation about permeability, mucus production and nutrient absorption, BP.IC
21/09662-2 - Insulin therapy in patients with COVID-19: a systematic review, BP.IC
21/07288-6 - Characterization of the molecular mechanisms that regulate adult neurogenesis in the hypothalamus in response to reproductive stimulus, BP.DR
21/06444-4 - Changes in maternal gut microbiota induced by fructose consumption during pregnancy: implications for the inflammatory allergic airway response in the offspring, BP.DR
21/08366-0 - Training in laboratory techniques of research on endocrine pancreas metabolism, BP.TT
21/04048-4 - Search for new adipocyte size regulators, BP.DR
20/14020-7 - Molecular and functional mechanisms involved in the central effects of FGF19 on hypothalamic dysregulation, BP.DR
21/08999-3 - Scientific dissemination as an instrument for disseminating knowledge about Obesity, BP.DR
21/01322-8 - Evaluation of the effects of interesterified fat on molecular mechanisms involved in the central control of energy homeostasis, BP.MS
21/04333-0 - Neural and behavioral evaluation during the aging of transgenic mice submitted to gestational protein restriction: investigation of Alzheimer's Disease-related proteins, BP.DR
21/01147-1 - Study of the influence of arginine metabolism on the immunometabolic profile of macrophages, BP.DD
20/12112-1 - Characterization of brown adipose tissue of individuals diagnosed with Congenital Ganeralized Lipodystrophy compared to obese dysmetabolic, obese eumetabolic and eutrophic eumetabolic, BP.DR
21/00443-6 - Evaluation of Kiss1 and Fezf1 neurons functions in adult hypothalamic neurogenesis triggered by hormones and nutritional stimuli, BP.PD
21/01221-7 - Complementary technical training, in the area of physiology and molecular biology, in the Laboratory of Cell Signaling, BP.TT
21/00509-7 - Multi-omic meta-analysis of the immune response to SARS-CoV-2: an integrated approach with cell resolution, BP.IC
20/07991-6 - Preparation and biological evaluation of phosphoryl and phosphonyl derivatives of goniothalamin and piplartine, BP.PD
20/09992-0 - The role of inflammation on GnRH synthesis in a hypothalamic cell line, BP.IC
19/17953-7 - Investigating the impact of fructose consumption on the airway inflammatory response during allergic asthma: focus on the gut microbiota, BE.PQ
20/05425-3 - Impact of adiponectin concentration on endothelial vasomotor function in patients with type 2 diabetes, BP.IC
20/09717-9 - Molecular mechanisms involved in cardiovascular changes triggered by fetal excess glucocorticoids, BP.DR
20/10102-9 - Study of the effects induced by GH receptor ablation in neurons of the lateral hypothalamic area, BP.PD
20/06057-8 - Exploring new mechanisms of intercellular communication in metabolic diseases, BP.PD
20/09112-0 - Effects evaluation of selective BDNF inhibition on FezF1 and Kiss1 hypothalamic neurons on the regulation of energy metabolism and thermogenesis, BP.DR
20/07257-0 - Hormonal, nutritional and inflammatory factors and microRNAs modulation related to the altered cholinergic anti-inflammatory response in Obesity, BP.PD
20/06397-3 - Study of cellular senescence in rodents subjected to Obesity, BP.PD
20/06661-2 - Role of alpha7nAChR cholinergic receptors in hypothalamic POMC neurons on the control of energy homeostasis in mice, BP.DR
20/03924-2 - Evaluation of the role of immunomodulation on brown adipose tissue activity in immunodeficient mice, BP.IC
20/07673-4 - Clinical trial for bradykinin inhibition in hospitalized adults with severe COVID-19, BP.PD
20/08489-2 - Combined effect of GLP-1 and GPRS 40 and 120 agonists in the treatment of experimental Obesity, BP.DR
20/05575-5 - Determination of molecular and cellular mechanisms involved in adult hypothalamus neurogenesis in response to reproductive stimuli, BP.PD
19/03751-3 - Influence of the history of Obesity originated at different moments of life in allergic pulmonary inflammation, BP.PD
19/19488-0 - The effect of agomelatine in human platelets aggregation and adhesion, BP.MS
19/23819-1 - Evaluation of Non-Transcriptional Pathways of High Density Lipoprotein-Mediated Ischemic Post-Conditioning, BP.DR
20/03956-1 - Investigation of the involvement of the microbiota-intestine-brain axis in the etiology of endocrine pancreatic dysfunction in mice subjected to protein malnutrition, BP.DR
20/04074-2 - The hypothalamic cellular ontology: a single-cell RNA sequencing integrative approach, BP.IC
20/02539-8 - TRAINING IN RESEARCH LABORATORY TECHNIQUES IN ENDOCRINE PANCREAS METABOLISM, BP.TT
18/17792-0 - HDL-S1P against pyroptosis damage after Acute Myocardial Infarction, BP.PD
19/00728-0 - The role of gut-pancreas axis upon glycemic homeostasis maintenance in obese mice submitted to vertical gastrectomy: a molecular and functional approach, BP.PD
18/17832-2 - EFFECTS OF INTERSTERIFIED FAT ON THE INTESTINAL PERMEABILITY OF HEALTHY AND OBESES ANIMALS, BP.PD
19/05210-0 - Evaluation of Interleukin-10 Modulation in Brown Adipose Tissue Termogenesis in Newborn: Therapeutic Strategies., BP.PD
18/19942-0 - Central role of GLP-1 agonists (liraglutide) and antiepileptic (topiramate) in treatment of high-fat diet-induced Obesity, BP.DR
19/00330-7 - Effect of palmitate treatment in pc1/3 expression in a hypothalamic cell lineage, BP.MS
16/24768-3 - Evaluation of metabolic parameters of experimental animal models in response to dietary interesterified fat: underlaying molecular mechanisms, BP.DR
18/01863-6 - Role of hypothalamic cholinergic receptor alpha7 (alpha7nAChR) in control of energy homeostasis and association with leptin signaling in mice, BP.MS
18/07970-9 - Complementary technical training, in the area of physiology and molecular biology, in the laboratory of cell signaling, BP.TT
17/22586-8 - Association between body composition and brown adipose tissue activity in human adults, BP.IC
18/00543-8 - The role of endothelial and macrophage mineralocorticoid receptor in inflammation response and anti-contractile function of perivascular adipose tissue in obese male and female, BP.PD
18/05979-9 - Training in research techniques of research on endocrine pancreas metabolism, BP.TT
16/00977-2 - Evaluation of expression and distribution of Nhlh2 protein in the hypothalamus of animals subjected to high fat diet, BP.DR
16/01245-5 - Evaluation of the involvement of TRIL in inflammation and apoptosis of POMC neurons in the hypothalamus of obese mice, BP.DR
17/13410-3 - Possible contribution of tauroursodeoxycholic acid (TUDCA) on the remission of type 2 diabetes in mice submitted to Duodenal-Jejunal Bypass, BP.PD
17/06245-6 - The role of a Peroxisome Proliferator-Activated Receptor Gamma agonist (PPAR-³) in the recruitment of inducible brown adipose tissue in humans by stabilizing proteins involved in the transcriptional cascade of adipogenesis, BP.IC
17/14298-2 - Combined effect of GLP-1 and GPRs 40 and 120 agonists in the treatment of experimental obesity, BP.DR
17/15382-7 - Assessment of theoretical and scientific knowledge diffusion on nutrition and healthy eating effectiveness for students, residents and healthcare professionals at UNICAMP, BP.IC
16/24289-8 - The role of pyruvate carboxylase on insulin sensitivity of skeletal muscle cells line of mice submitted to aminoacids deprivation: Involviment of ACILCARNITINES, BP.PD
17/06146-8 - Development of nanocarriers based on dendrimers and polymer nanoparticles for selective delivery of goniothalamin, piplartine and Monastrol, BP.PD
17/11138-4 - Effect of pregnancy followed by lactation on miRNAs modulation of maternal pancreatic islets, BP.IC
16/20472-2 - Evaluation of the long-term changes in the lipid profile of woman that underwent antenatal corticotherapy during pregnancy, BP.IC
17/06389-8 - Effects of circadian misalignment on brown adipose tissue activity in humans, BP.IC
17/08200-0 - Evaluation of serum factors effects obtained from mice with and without predisposition to obesity on inflammatory aspects in microglia line and hypothalamic neurons, BP.IC
16/25783-6 - Molecular and functional analysis of taurine action on apoptosis and redox balance pathways in cells/tissues submitted to amino acid restriction, BP.PD
16/23833-6 - Role of alpha7 nicotinic acetylcholine receptor (alpha7nAChR) in preventing insulin resistance in hypothalamic cells., BP.DR
16/09270-9 - Orexin participation in the interaction between hunger and reward control systems in spontaneously lean and obese animals kept with normocaloric diet, BP.PD
16/14461-8 - In vivo and in vitro endothelial effects of taurine in protein restriction, BP.PD
16/20488-6 - Evaluation of the long-term changes in insulin sensitivity of woman that underwent antenatal corticotherapy during pregnancy, BP.IC
16/17102-9 - Function of myostatin in epigenetic control of pancreatic beta cells proliferation, BP.PD
16/07361-7 - The role of maternal obesity on modulation of offspring hypothalamic miRNAs and metabolic consequences associated, BP.PD
16/08865-9 - Modulation of adiponectin receptor AdipoR1 and miR-221 in skeletal muscle of trained and high-fat diet fed C57BL/6 mice, BP.IC
16/10616-7 - Effect of monounsaturated fatty acids consumption in brown/beige adipose tissue activity in human adults, BP.PD
16/05312-9 - Effect of a new inhibitor of adenosine kinase (ADK) in energetic metabolism in obese mice, BP.PD
16/08569-0 - Synthesis of glibenclamide new derivatives in order to obtain potential antihyperglycemic drugs, BP.PD
15/25710-6 - Hypothalamic autophagy evaluation in response to treatment with saturated fatty acid in vitro and in vivo: connections with inflammatory pathways, BP.DR
16/03047-6 - MicroRNAs analysis in the hypothalamus of trained and high fat diet-fed C57BL/6 mice, BP.IC
16/04723-5 - The influence of gut microbiota in blood pressure modulation of rodents: the role of hydrogen sulfide (H2S) and short-chain fatty acids., BP.DR
16/04256-8 - Subcutaneous adipose tissue formation mechanisms in a lymphedema experimental model, BP.IC
15/20353-0 - Hemodynamic responses of 0.9% saline solution infusion in obese resistant hypertensive patients, BP.IC
15/10078-2 - Effect of a high caloric diet in the expression of Hypoxia- inducible factor-1 (HIF1): Role in obesity through deregulation of pomc gene, BP.PD
15/23285-6 - Endocrine pancreas maturation and differentiation in offspring of females submitted to dexamethasone treatment during pregnancy, BP.PD
15/23969-2 - "EFFECTS OF DAPAGLIFLOZIN A SGLT2 INHIBITOR ON BLOOD PRESSURE, CARDIOVASCULAR REMODELING AND OBESITY PROFILE IN RESISTANT HYPERTENSION SUBJECTS ", BP.DR
15/25597-5 - Hepatic microRNA expression profile in Goto-Kakizaki rats and Wistar rats subjected to metabolic programming by prenatal exposure to glucocorticoid excess, BP.DR
15/12020-1 - The effects of body mass reduction on the blood levels of Th17 family citokynes in subjects submitted to Roux-en-Y gastric bypass, BP.IC
14/05635-7 - Genetic polymorphisms of matrix metalloproteinases in resistant hypertension, BE.PQ
14/26591-8 - Acute effect of dapagliflozin SGLT-2 inhibitory on brain and hypothalamic functionality in humans and mice C57BL/6, BP.MS
14/07496-4 - Role of the transcription factor IRX3 in inducing hypothalamic neurogenesis in adult mice, BP.PD
14/26942-5 - Evaluation of intracerebroventricular treatment effect with selective agonists of GPR120 and GPR40 receptors and in high fat diet induced-obesity mice, BP.PD
15/02913-9 - Structural and molecular analysis of the hypotalamus median eminence of mice born from high fat diet fed mothers, BP.PD
15/03645-8 - Hormone peptides PYY and TFF2 action on leptin signaling pathway in CLU189 cells, BP.IC
15/00360-2 - Cardiac and renal effects in rats offspring subjected to protein restriction during gestation and lactation: influence of enriched environment on these effects, BP.IC
14/24050-0 - The role of hypothalamic stearoil-CoA 2 (SCD2) in neurogenesis de novo, BP.IC
14/24515-2 - Role of inflammassome in hypothalamic inflammation in response to hyperlipidic diet, BP.IC
14/17384-9 - Autophagy in hypothalamic neurons in obesity, BP.PD
14/09532-8 - Functional and molecular analysis of estrogen receptors in the islets of Langerhans and peripheral tissues of malnourished mice and their involvement in glycemic control, BP.PD
14/09118-7 - The involvement of microRNAs in the accelerated ageing process caused by obesity and the potential intervention by caloric restriction, fatty acid supplementation and exercise, BP.PD
14/00742-0 - Characterization of rapid POMC regulation mechanisms involved in high-fat diet response, BP.PD
14/06840-3 - BMP-SMADs pathway in the pancreatic beta cell as a modulator of glucose-stimulated insulin secretion, BP.PD
14/03285-9 - Obesity and target organs damage in resistant hypertension: role of metaloproteinases, BP.PD
13/24026-9 - Evaluation of the role of dsRNA-dependent protein kinase (PKR) in the pathogenesis of insulin resistance and intestinal permeability in obesity., BP.PD
13/25847-6 - INVOLVEMENT OF THE AUTONOMIC NERVOUS SYSTEM UPON GLUCOSE CONTROL AND PANCREATIC ISLETS FUNCTION IN MALNOURISHED MICE FED A HIGH-FAT DIET, BP.DR
14/02977-4 - Epigenetic mechanisms associated with obesity and chronic inflammation, BP.PD
13/26319-3 - Evaluation of the temporal progression of the installation of inflammation, endoplasmic reticulum stress and mitochondrial dysfunction in the hypothalamus of mice subjected to a high fat diet, BP.MS
14/02819-0 - Investigation of glucose and lipid metabolism alterations in a model of nicotinamide nucleotide transhydrogenase mitochondrial (NNT)deficiency ., BP.DR
14/03905-7 - Circadian modulation of peripheral insulin sensitivity in malnourished mice submitted to hyperlipidic diet, BP.IC
13/25415-9 - Evaluation Of Adaptive Immune Response in Inflammation of the Hypothalamus in Obesity, BP.DR
13/22815-6 - Distribution of adipocytes, adipocytokines and cardiovascular characteristics in individuals with spinal cord injury, BP.IC
13/20539-1 - Analysis of the neural effects of in utero protein restriction in rats subjected or not to caloric overload: study parameters neuro-behavioral, morpho-functional molecular and during development in rats, BP.DR
13/22321-3 - Chronic insulin receptor blockade in amygdala: effects on energy metabolism, BP.IC
13/22276-8 - Role of hypothalamic stearoyl-CoA desaturase 2 in neuronal apoptosis and obesity, BP.PD
12/17416-2 - REGULATION OF MITOCHONDRIAL FUNCTION AND METABOLISM OF GLUCOSE AND FATTY ACIDS BY FACTOR OF HYPOXIA INDUCIBLE (HIF-1a) MUSCLE CELLS IN INSULIN RESISTANCE, BP.PD
12/24629-2 - Insulin signaling pathway and HSR action in rodent longevity., BP.PD
12/02669-2 - MOLECULAR MECANISMS OF PULMONARY ARTERIAL HYPERTENSION ASSOCIATED TO INSULIN RESISTANCE: STUDIES IN ANIMAL MODEL OF OBESITY., BP.PD
11/22217-6 - Modulation of Amino Acids metabolism in Muscle and Adipose Tissue: Effects of Physical Exercise and Bariatric Gastric Bypass Surgery., BP.PD - associated scholarships

Abstract

Obesity affects more than 400 million subjects in the world and projections for the next 15 years predict an overall prevalence of up to 20%. In developing countries, such as Brazil a rapid nutritional transition provided by the recent economical growth has led to a unique condition on which the malnourished persist in parallel with an increasing number of obese subjects. It is expected that by the year 2020 up to 20% Brazilians will be obese and approximately 50%, overweigh. Obesity is highly associated with a number of diseases such as diabetes, hypertension, atherosclerosis and certain types of cancer. Because of the absolute lack of appropriate preventive and therapeutic approaches to deal with obesity, the overall mortality directly and indirectly associated with this disease is rapidly increasing in the world. Obesity results from an imbalance between caloric intake and energy expenditure. Although great advance was recently obtained in the characterization of the mechanisms of control of feeding and thermogenesis, the complexity of the neural circuits that control these functions and the difficulties imposed by anatomical constrains to study human hypothalamus, have contributed to hamper a rapid advance in the treatment of obesity. The main objective of OCRC is to coordinate the efforts to find solutions for obesity and associated diseases. Some of the most productive Brazilian scientists in these fields will work in concert to provide advance in the understanding of the mechanisms leading to obesity and its associated conditions. In addition, the search for new pharmacological nutritional and physical activity approaches to deal with these diseases will be pursued. Regarding education, OCRC will invest on the orientation of high-school students and senior citizens regarding preventive and screening methods for early detection of these diseases. Also, OCRC will foster programs for improving the education of undergraduate students in the field of nutrition and increasing the interest for research in these fields. Finally, OCRC staff will be in contact with industry and other potential users of the knowledge and products obtained in order to speed up the transfer of knowledge to society. (AU)

Articles published in Pesquisa FAPESP Magazine about the research grant:
Hormonas maternas afectan áreas cerebrales que controlan el hambre y la saciedad en el feto 
Maternal hormones affect brain areas that control hunger and satiety in the fetus 
A delicate balance 
Un equilibrio delicado 
Articles published in Agência FAPESP Newsletter about the research grant:
Articles published in other media outlets (0 total):
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (161)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SANTOS, ROBERTA S.; BATISTA, THIAGO M.; CAMARGO, RAFAEL L.; MORATO, PRISCILA N.; BORCK, PATRICIA C.; LEITE, NAYARA C.; KURAUTI, MIRIAN A.; WANSCHEL, AMARYLIS C. B. A.; NADAL, ANGEL; CLEGG, DEBORAH J.; et al. Lacking of estradiol reduces insulin exocytosis from pancreatic beta-cells and increases hepatic insulin degradation. Steroids, v. 114, n. SI, p. 16-24, . (15/05801-7, 13/07607-8)
BOUCHARD, CLAUDE; ANTUNES-CORREA, LIGIA M.; ASHLEY, EUAN A.; FRANKLIN, NINA; HWANG, PAUL M.; MATTSSON, C. MIKAEL; NEGRAO, CARLOS E.; PHILLIPS, SHANE A.; SARZYNSKI, MARK A.; WANG, PING-YUAN; et al. Personalized Preventive Medicine: Genetics and the Response to Regular Exercise in Preventive Interventionse. PROGRESS IN CARDIOVASCULAR DISEASES, v. 57, n. 4, p. 337-346, . (10/50048-1, 13/15651-7, 13/07607-8)
BUSANELLO, ESTELA N. B.; FIGUEIRA, TIAGO R.; MARQUES, ANA C.; NAVARRO, CLAUDIA D. C.; OLIVEIRA, HELENA C. F.; VERCESI, ANIBAL E.. Facilitation of Ca2+-induced opening of the mitochondrial permeability transition pore either by nicotinamide nucleotide transhydrogenase deficiency or statins treatment. Cell Biology International, v. 42, n. 6, p. 5-pg., . (11/50400-0, 06/59786-0, 14/11261-2, 13/07607-8)
ROSA, LUCAS RODOLFO DE OLIVEIRA; VETTORAZZI, JEAN FRANCIESCO; ZANGEROLAMO, LUCAS; CARNEIRO, EVERARDO MAGALHAES; BARBOSA, HELENA CRISTINA DE LIMA. UDCA receptors and their role on pancreatic beta cell. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, v. 167, p. 26-31, . (19/23951-7, 12/14993-9, 15/12611-0, 13/07607-8, 18/06363-1)
MARTINS, I. C. A.; CONTIERI, L. S.; AMARAL, C. L.; COSTA, S. O.; SOUZA, A. C. P.; IGNACIO-SOUZA, L. M.; MILANSKI, M.; TORSONI, A. S.; TORSONI, M. A.. Omega-3 Supplementation Prevents Short-Term High-Fat Diet Effects on the alpha 7 Nicotinic Cholinergic Receptor Expression and Inflammatory Response. Mediators of Inflammation, v. 2021, . (16/23484-1, 18/01863-6, 13/07607-8, 19/07615-7)
ZANGEROLAMO, LUCAS; VETTORAZZI, JEAN F.; SOLON, CARINA; BRONCZEK, GABRIELA A.; ENGEL, DAIANE F.; KURAUTI, MIRIAN A.; SOARES, GABRIELA M.; RODRIGUES, KARINA S.; VELLOSO, LICIO A.; BOSCHERO, ANTONIO C.; et al. The bile acid TUDCA improves glucose metabolism in streptozotocin-induced Alzheimer's disease mice model. Molecular and Cellular Endocrinology, v. 521, . (13/07607-8, 15/12611-0, 17/13410-3, 15/23729-1, 18/06363-1, 18/20213-2)
MANSOUR, ELI; BUENO, FLAVIA F.; DE LIMA-JUNIOR, JOSE C.; PALMA, ANDRE; MONFORT-PIRES, MILENA; BOMBASSARO, BRUNA; ARAUJO, ELIANA P.; BERNARDES, ANA FLAVIA; ULAF, RAISA G.; NUNES, THYAGO A.; et al. Evaluation of the efficacy and safety of icatibant and C1 esterase/kallikrein inhibitor in severe COVID-19: study protocol for a three-armed randomized controlled trial. Trials, v. 22, n. 1, . (13/07607-8, 20/04522-5)
RIBEIRO, LUCIANA C.; BENITES, BRUNO DELTREGGIA; ULAF, RAISA G.; NUNES, THYAGO A.; COSTA-LIMA, CAROLINA; ADDAS-CARVALHO, MARCELO; PROENCA-MODENA, JOSE LUIZ; GRANJA, FABIANA; DA COSTA, VITOR ANTONIO; SANTOS DUARTE, ADRIANA DA SILVA; et al. Rapid clinical recovery of a SARS-CoV-2 infected common variable immunodeficiency patient following the infusion of COVID-19 convalescent plasma. ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, v. 17, n. 1, . (20/04558-0, 20/04522-5, 13/07607-8, 16/00194-8)
PASCOAL, LIVIA BITENCOURT; RODRIGUES, PATRICIA BRITO; GENARO, LIVIA MOREIRA; DOS SANTOS PEREIRA GOMES, ARILSON BERNARDO; TOLEDO-TEIXEIRA, DANIEL AUGUSTO; PARISE, PIERINA LORENCINI; BISPO-DOS-SANTOS, KARINA; SIMEONI, CAMILA LOPES; GUIMARAES, PAULA VERI; BUSCARATTI, LUCAS ILDEFONSO; et al. Microbiota-derived short-chain fatty acids do not interfere with SARS-CoV-2 infection of human colonic samples. GUT MICROBES, v. 13, n. 1, p. 1-9, . (20/04558-0, 20/04583-4, 20/02448-2, 20/02312-3, 19/14342-7, 20/04746-0, 17/26908-0, 20/04579-7, 20/04919-2, 19/06372-3, 13/07607-8, 20/02159-0)
PILLI, RONALDO ALOISE; DE TOLEDO, IAN; MEIRELLES, MATHEUS ANDRADE; GRIGOLO, THIAGO AUGUSTO. Goniothalamin-Related Styryl Lactones: Isolation, Synthesis, Biological Activity and Mode of Action. Current Medicinal Chemistry, v. 26, n. 41, p. 7372-7451, . (16/12541-4, 13/07607-8)
TEIXEIRA, CAIO JORDAO; SANTOS-SILVA, JUNIA CAROLINA; DE SOUZA, DAILSON NOGUEIRA; RAFACHO, ALEX; ANHE, GABRIEL FORATO; BORDIN, SILVANA. Dexamethasone during pregnancy impairs maternal pancreatic beta-cell renewal during lactation. ENDOCRINE CONNECTIONS, v. 8, n. 2, p. 120-131, . (13/07607-8)
DE TOLEDO, IAN; GRIGOLO, THIAGO; BENNETT, JAMES M.; ELKINS, JONATHAN M.; PILLI, RONALDO A.. Modular Synthesis of Di- and Trisubstituted Imidazoles from Ketones and Aldehydes: A Route to Kinase Inhibitors. Journal of Organic Chemistry, v. 84, n. 21, p. 14187-14201, . (13/07607-8, 19/13104-5)
MENDES, NATALIA FERREIRA; CASTRO, GISELE; GUADAGNINI, DIOZE; TOBAR, NATALIA; COGNUCK, SUSANA QUIROS; KAGOHARA ELIAS, LUCILA LEICO; BOER, PATRICIA ALINE; PRADA, PATRICIA OLIVEIRA. Knocking down amygdalar PTP1B in diet-induced obese rats improves insulin signaling/action, decreases adiposity and may alter anxiety behavior. METABOLISM-CLINICAL AND EXPERIMENTAL, v. 70, p. 1-11, . (15/00343-0, 13/07607-8)
MORSELLI, EUGENIA; SANTOS, ROBERTA S.; CRIOLLO, ALFREDO; NELSON, MICHAEL D.; PALMER, BIFF F.; CLEGG, DEBORAH J.. The effects of oestrogens and their receptors on cardiometabolic health. NATURE REVIEWS ENDOCRINOLOGY, v. 13, n. 6, p. 352-364, . (13/07607-8)
GUIZONI, DANIELE M.; FREITAS, ISRAELLE N.; VICTORIO, JAMAIRA A.; POSSEBOM, ISABELA R.; ARAUJO, THIAGO R.; CARNEIRO, EVERARDO M.; DAVEL, ANA P.. Taurine treatment reverses protein malnutrition-induced endothelial dysfunction of the pancreatic vasculature: The role of hydrogen sulfide. METABOLISM-CLINICAL AND EXPERIMENTAL, v. 116, . (14/01717-9, 13/07607-8, 16/14461-8)
ZANGEROLAMO, LUCAS; VETTORAZZI, JEAN F.; ROSA, LUCAS R. O.; CARNEIRO, EVERARDO M.; BARBOSA, HELENA C. L.. The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sciences, v. 272, . (13/07607-8, 18/06363-1, 15/23729-1, 18/20213-2, 15/12611-0)
MOURA-ASSIS, ALEXANDRE; FRIEDMAN, JEFFREY M.; VELLOSO, LICIO A.. Gut-to-brain signals in feeding control. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, v. 320, n. 2, p. E326-E332, . (13/07607-8)
ROCHA, WALTER E. M.; OLIVEIRA, MATHEUS F. R. A.; SOARES, JULIA D.; L'ARMEE, VICTOR M. F. S.; MARTINS, MAYARA P. G.; ROCHA, ALOISIO M.; FEITOSA, AUDES D. M.; LIMA, RICARDO C.; OLIVEIRA, PEDRO P. M.; SILVEIRA-FILHO, LINDEMBERG M.; et al. Left Ventricular Concentric Geometric Patterns Are Associated With Worse Prognosis Among Patients With Type-A Aortic Dissection. JOURNAL OF THE AMERICAN HEART ASSOCIATION, v. 10, n. 5, . (13/07607-8)
MENDES, NATALIA FERREIRA; JARA, CARLOS POBLETE; ZANESCO, ARIANE MARIA; DE ARAUJO, ELIANA PEREIRA. Hypothalamic Microglial Heterogeneity and Signature under High Fat Diet-Induced Inflammation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 22, n. 5, . (19/00330-7, 17/22511-8, 16/17810-3, 13/07607-8)
ZANGEROLAMO, LUCAS; SOLON, CARINA; SOARES, GABRIELA M.; ENGEL, DAIANE F.; VELLOSO, LICIO A.; BOSCHERO, ANTONIO C.; CARNEIRO, EVERARDO M.; BARBOSA, HELENA CRISTINA L.. Energy homeostasis deregulation is attenuated by TUDCA treatment in streptozotocin-induced Alzheimer's disease mice model. SCIENTIFIC REPORTS, v. 11, n. 1, . (13/07607-8, 18/20213-2, 18/06363-1)
GRIGOLO, THIAGO A.; BRAGA, CAROLYNE B.; ORNELAS, CATIA; RUSSOWSKY, DENNIS; FERREIRA-SILVA, GUILHERME A.; IONTA, MARISA; PILLI, RONALDO A.. Hybrids of 4-hydroxy derivatives of goniothalamin and piplartine bearing a diester or a 1,2,3-triazole linker as antiproliferative agents. BIOORGANIC CHEMISTRY, v. 116, . (17/06146-8, 18/02093-0, 13/07607-8, 19/13104-5)
PASTRE, JULIO C.; MURRAY, PHILIP R. D.; BROWNE, DUNCAN L.; BRANCAGLION, GUILHERME A.; GALAVERNA, RENAN S.; PILLI, RONALDO A.; LEY, V, STEVEN. Integrated Batch and Continuous Flow Process for the Synthesis of Goniothalamin. ACS OMEGA, v. 5, n. 29, p. 18472-18483, . (13/07607-8, 12/05909-4, 14/26378-2)
MEIRELLES, MATHEUS A.; BRAGA, CAROLYNE B.; ORNELAS, CATIA; PILLI, RONALDO A.. Synthesis of Nitrogen-Containing Goniothalamin Analogues with Higher Cytotoxic Activity and Selectivity against Cancer Cells. CHEMMEDCHEM, v. 14, n. 15, . (13/07607-8, 18/02093-0, 17/06146-8)
BOBBO, VANESSA C. D.; JARA, CARLOS P.; MENDES, NATALIA F.; MORARI, JOSEANE; VELLOSO, LICIO A.; ARAUJO, ELIANA P.. Interleukin-6 Expression by Hypothalamic Microglia in Multiple Inflammatory Contexts: A Systematic Review. BIOMED RESEARCH INTERNATIONAL, v. 2019, . (13/07607-8)
RAITZ, ISMAEL; DE SOUZA FILHO, ROBERTO Y.; DE ANDRADE, LORENA P.; CORREA, JOSE R.; NETO, BRENNO A. D.; PILLI, RONALDO A.. Preferential Mitochondrial Localization of a Goniothalamin Fluorescent Derivative. ACS OMEGA, v. 2, n. 7, p. 3774-3784, . (09/51602-5, 16/12541-4, 13/07607-8)
-FELICE, FRANCO DELLA; SAROTTI, ARIEL M.; PILLI, RONALDO A.. Catalytic Asymmetric Synthesis and Stereochemical Revision of (+)-Cryptoconcatone H. Journal of Organic Chemistry, v. 82, n. 17, p. 9191-9197, . (14/25474-8, 16/12541-4, 13/07607-8)
DABAJA, MOHAMED ZIAD; LIMA, ESTELA DE OLIVEIRA; DE OLIVEIRA, DIOGO NOIN; GUERREIRO, TATIANE MELINA; ODIR RODRIGUES MELO, CARLOS FERNANDO; MORISHITA, KAREN NODA; LANCELLOTTI, MARCELO; TASCA GOIS RUIZ, ANA LUCIA; GOULART, GISELE; DUARTE, DIEGO ANDREAZZI; et al. Metabolic alterations induced by attenuated Zika virus in glioblastoma cells. CELL AND BIOSCIENCE, v. 8, . (15/06809-1, 11/50400-0, 16/17066-2, 13/07607-8)
MENDES, NATALIA F.; KIM, YOUNG-BUM; VELLOSO, LICIO A.; ARAUJO, ELIANA P.. Hypothalamic Microglial Activation in Obesity: A Mini-Review. FRONTIERS IN NEUROSCIENCE, v. 12, . (17/22511-8, 13/07607-8, 17/02983-2, 16/17810-3)
DORIGHELLO, GABRIEL G.; PAIM, BRUNO A.; LEITE, ANA CATARINA R.; VERCESI, ANIBAL E.; OLIVEIRA, HELENA C. F.. Spontaneous experimental atherosclerosis in hypercholesterolemic mice advances with ageing and correlates with mitochondrial reactive oxygen species. Experimental Gerontology, v. 109, n. SI, p. 47-50, . (11/50400-0, 13/07607-8)
KURAUTI, MIRIAN A.; COSTA-JUNIOR, JOSE M.; FERREIRA, SANDRA M.; DOS SANTOS, GUSTAVO J.; PROTZEK, ANDRE O. P.; NARDELLI, TARLLIZA R.; DE REZENDE, LUIZ F.; BOSCHERO, ANTONIO C.. Acute exercise restores insulin clearance in diet-induced obese mice. Journal of Endocrinology, v. 229, n. 3, p. 221-232, . (13/21283-0, 13/07607-8)
VICENTE, JULIA MODESTO; TEIXEIRA, CAIO JORDAO; SANTOS-SILVA, JUNIA CAROLINA; DE SOUZA, DAILSON NOGUEIRA; TOBAR, NATALIA; FURTUOSO, FABIOLA SALES; ADABO, ISABEL GOUVEIA; SODRE, FRHANCIELLY SHIRLEY; MURATA, GILSON; BORDIN, SILVANA; et al. The absence of lactation after pregnancy induces long-term lipid accumulation in maternal liver of mice. Life Sciences, v. 217, p. 261-270, . (13/07607-8, 15/12680-1)
MENDES, NATALIA F.; GASPAR, JOANA M.; LIMA-JUNIOR, JOSE C.; DONATO, JR., JOSE; VELLOSO, LICIO A.; ARAUJO, ELIANA P.. TGF-beta 1 down-regulation in the mediobasal hypothalamus attenuates hypothalamic inflammation and protects against diet-induced obesity. METABOLISM-CLINICAL AND EXPERIMENTAL, v. 85, p. 171-182, . (17/02983-2, 15/10078-2, 13/07607-8, 16/17810-3)
LORZA-GIL, ESTELA; DE SOUZA, JANE C.; GARCIA-AREVALO, MARTA; VETTORAZZI, JEAN F.; MARQUES, ANA CAROLINA; SALERNO, ALESSANDRO G.; TRIGO, JOSE ROBERTO; OLIVEIRA, HELENA C. F.. Coenzyme Q(10) protects against -cell toxicity induced by pravastatin treatment of hypercholesterolemia. Journal of Cellular Physiology, v. 234, n. 7, p. 11047-11059, . (11/50400-0, 13/07607-8)
MORARI, JOSEANE; HADDAD-TOVOLLI, ROBERTA; SILVA NOGUEIRA, PEDRO AUGUSTO; TEIXEIRA, CAIO JORDAO; MAROSTICA, RAFAEL; TOBAR, NATALIA; RAMOS, CELSO DARIO; VELLOSO, LICIO AUGUSTO; DIAS BOBBO, VANESSA CRISTINA; ANHE, GABRIEL FORATO. Body mass variability in age-matched outbred male Swiss mice is associated to differential control of food intake by ghrelin. Molecular and Cellular Endocrinology, v. 550, p. 10-pg., . (13/07607-8, 16/09270-9)
LOPES, ELISANGELA C. P.; PAIM, LAYDE R.; CARVALHO-ROMANO, LUIS F. R. S.; MARQUES, EDMILSON R.; MININ, EDUARDA O. Z.; VEGIAN, CAMILA F. L.; PIO-MAGALHAES, JOSE A.; VELLOSO, LICIO A.; COELHO-FILHO, OTAVIO R.; SPOSITO, ANDREI C.; et al. Relationship Between Circulating MicroRNAs and Left Ventricular Hypertrophy in Hypertensive Patients. FRONTIERS IN CARDIOVASCULAR MEDICINE, v. 9, p. 9-pg., . (17/23563-1, 13/07607-8)
SANTOS-SILVA, JUNIA CAROLINA; DA SILVA, PRISCILLA MUNIZ RIBEIRO; DE SOUZA, DAILSON NOGUEIRA; TEIXEIRA, CAIO JORDAO; BORDIN, SILVANA; ANHE, GABRIEL FORATO. In utero exposure to dexamethasone programs the development of the pancreatic beta- and alpha-cells during early postnatal life. Life Sciences, v. 255, . (15/23285-6, 13/07607-8)
DRAGANO, NATHALIA R.; MONFORT-PIRES, MILENA; VELLOSO, LICIO A.. Mechanisms Mediating the Actions of Fatty Acids in the Hypothalamus. Neuroscience, v. 447, p. 15-27, . (13/07607-8)
PEREIRA, GIZELA A.; SODRE, FRHANCIELLY S.; MURATA, GILSON M.; AMARAL, ANDRESSA G.; PAYOLLA, TANYARA B.; CAMPOS, CAROLINA V.; SATO, FABIO T.; ANHE, GABRIEL F.; BORDIN, SILVANA. Fructose Consumption by Adult Rats Exposed to Dexamethasone In Utero Changes the Phenotype of Intestinal Epithelial Cells and Exacerbates Intestinal Gluconeogenesis. NUTRIENTS, v. 12, n. 10, . (19/03196-0, 13/07607-8)
DE OLIVEIRA, DIOGO N.; LIMA, ESTELA O.; MELO, CARLOS F. O. R.; DELAFIORI, JEANY; GUERREIRO, TATIANE M.; RODRIGUES, RAFAEL G. M.; MORISHITA, KAREN N.; SILVEIRA, CYNTHIA; MURARO, STEFANIE PRIMON; DE SOUZA, GABRIELA FABIANO; et al. Inflammation markers in the saliva of infants born from Zika-infected mothers: exploring potential mechanisms of microcephaly during fetal development. SCIENTIFIC REPORTS, v. 9, . (18/03321-6, 11/50400-0, 13/07607-8, 16/17066-2)
OLIVEIRA, MATHEUS F. R. A.; ROCHA, WALTER E. M.; SOARES, JULIA D.; L'ARMEE, VICTOR M. F. S.; MARTINS, MAYARA P. G.; ROCHA, ALOISIO M.; FEITOSA, AUDES D. M.; LIMA, RICARDO C.; OLIVEIRA, PEDRO P. M.; SILVEIRA-FILHO, LINDEMBERG M.; et al. mpact of Hypertension History and Blood Pressure at Presentation on Cardiac Remodeling and Mortality in Aortic Dissectio. FRONTIERS IN CARDIOVASCULAR MEDICINE, v. 8, . (13/07607-8)
ANHE, GABRIEL FORATO; BORDIN, SILVANA. The adaptation of maternal energy metabolism to lactation and its underlying mechanisms. Molecular and Cellular Endocrinology, v. 553, p. 22-pg., . (13/07607-8, 20/13940-5, 19/03196-0)
DE OLIVEIRA, K. M.; ALVES, B. L.; SILVA JUNIOR, J. A.; SOARES, G. M.; MOUSOVICH-NETO, F.; RIBEIRO, R. A.; CARNEIRO, E. M.. Effects of protein restriction on glucose tolerance and large intestine morphofunction in C57Bl/6 mice. Diabetologia, v. 65, n. SUPPL 1, p. 1-pg., . (18/26080-4, 20/03956-1, 13/07607-8)
DE SOUZA, DAILSON NOGUEIRA; TEIXEIRA, CAIO JORDAO; VERONESI, VANESSA BARBOSA; MURATA, GILSON MASAHIRO; SANTOS-SILVA, JUNIA CAROLINA; HECHT, FERNANDA BALLERINI; VICENTE, JULIA MODESTO; BORDIN, SILVANA; ANHE, GABRIEL FORATO. Dexamethasone programs lower fatty acid absorption and reduced PPAR-gamma and fat/CD36 expression in the jejunum of the adult rat offspring. Life Sciences, v. 265, . (13/07607-8, 20/06397-3, 19/03196-0, 16/13138-9, 15/23285-6)
POBLETE JARA, CARLOS; NOGUEIRA, GUILHERME; MORARI, JOSEANE; DO PRADO, THAIS PAULINO; DE MEDEIROS BEZERRA, RENAN; VELLOSO, LICIO A.; VELANDER, WILLIAM; DE ARAUJO, ELIANA PEREIRA. An older diabetes-induced mice model for studying skin wound healing. PLoS One, v. 18, n. 2, p. 21-pg., . (13/07607-8)
RIBEIRO, LUCIANA C.; BENITES, BRUNO DELTREGGIA; ULAF, RAISA G.; NUNES, THYAGO A.; COSTA-LIMA, CAROLINA; ADDAS-CARVALHO, MARCELO; PROENCA-MODENA, JOSE LUIZ; GRANJA, FABIANA; DA COSTA, VITOR ANTONIO; SANTOS DUARTE, ADRIANA DA SILVA; et al. Rapid clinical recovery of a SARS-CoV-2 infected common variable immunodeficiency patient following the infusion of COVID-19 convalescent plasma. ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, v. 17, n. 1, p. 4-pg., . (13/07607-8, 16/00194-8, 20/04522-5, 20/04558-0)
CARVALHO-ROMANO, LUIS F. R. S.; BONAFE, RAFAEL P.; PAIM, LAYDE R.; MARQUES, EDMILSON R.; VEGIAN, CAMILA F. L.; PIO-MAGALHAES, JOSE A.; MELLO, DANIEL S. S.; DE ROSSI, GUILHERME; COELHO-FILHO, OTAVIO R.; SCHREIBER, ROBERTO; et al. Association of carotid wall layers with atherosclerotic plaques and cardiac hypertrophy in hypertensive subjects. JOURNAL OF HUMAN HYPERTENSION, v. 36, n. 8, p. 6-pg., . (13/07607-8)
BUSANELLO, ESTELA N. B.; FIGUEIRA, TIAGO R.; MARQUES, ANA C.; NAVARRO, CLAUDIA D. C.; OLIVEIRA, HELENA C. F.; VERCESI, ANIBAL E.. Facilitation of Ca2+-induced opening of the mitochondrial permeability transition pore either by nicotinamide nucleotide transhydrogenase deficiency or statins treatment. Cell Biology International, v. 42, n. 6, SI, p. 742-746, . (06/59786-0, 11/50400-0, 14/11261-2, 13/07607-8)
NAVARRO, CLAUDIA D. C.; FIGUEIRA, TIAGO R.; FRANCISCO, ANNELISE; DAL'BO, GENOEFA A.; RONCHI, JULIANA A.; ROVANI, JULIANA C.; ESCANHOELA, CECILIA A. F.; OLIVEIRA, HELENA C. F.; CASTILHO, ROGER F.; VERCESI, ANIBAL E.. Redox imbalance due to the loss of mitochondrial NAD(P)-transhydrogenase markedly aggravates high fat diet-induced fatty liver disease in mice. Free Radical Biology and Medicine, v. 113, p. 190-202, . (14/02819-0, 11/50400-0, 15/22063-0, 13/07607-8)
PAIVA, ADRIENE A.; RAPOSO, HELENA F.; WANSCHEL, AMARYLIS C. B. A.; NARDELLI, TARLLIZA R.; OLIVEIRA, HELENA C. F.. Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, . (11/50400-0, 13/07607-8)
DE PAULA SIMINO, LAIS ANGELICA; DE FANTE, THAIS; FONTANA, MARINA FIGUEIREDO; BORGES, FERNANDA OLIVEIRA; TORSONI, MARCIO ALBERTO; MILANSKI, MARCIANE; VELLOSO, LICIO AUGUSTO; TORSONI, ADRIANA SOUZA. Lipid overload during gestation and lactation can independently alter lipid homeostasis in offspring and promote metabolic impairment after new challenge to high-fat diet. NUTRITION & METABOLISM, v. 14, . (11/22156-7, 13/07607-8, 14/18165-9)
ZANOTTO, TAMIRES M.; QUARESMA, PAULA G. F.; GUADAGNINI, DIOZE; WEISSMANN, LAIS; SANTOS, ANDRESSA C.; VECINA, JULIANA F.; CALISTO, KELLY; SANTOS, ANDREY; PRADA, PATRCIA O.; SAAD, MARIO J. A.. Blocking iNOS and endoplasmic reticulum stress synergistically improves insulin resistance in mice. MOLECULAR METABOLISM, v. 6, n. 2, . (12/15009-0, 13/07607-8, 16/07122-2)
MANSOUR, ELI; PALMA, ANDRE C.; ULAF, RAISA G.; RIBEIRO, LUCIANA C.; BERNARDES, ANA FLAVIA; NUNES, THYAGO A.; AGRELA, V, MARCUS; BOMBASSARO, BRUNA; MONFORT-PIRES, MILENA; CAMARGO, RAFAEL L.; et al. Safety and Outcomes Associated with the Pharmacological Inhibition of the Kinin-Kallikrein System in Severe COVID-19. Viruses-Basel, v. 13, n. 2, . (20/04522-5, 13/07607-8)
ENGEL, DAIANE F.; BOBBO, VANESSA C. D.; SOLON, CARINA S.; NOGUEIRA, GUILHERME A.; MOURA-ASSIS, ALEXANDRE; MENDES, NATALIA F.; ZANESCO, ARIANE M.; PAPANGELIS, ATHANASIOS; ULVEN, TROND; VELLOSO, LICIO A.. Activation of GPR40 induces hypothalamic neurogenesis through p38-and BDNF-dependent mechanisms. SCIENTIFIC REPORTS, v. 10, n. 1, . (13/07607-8, 14/50938-8, 18/01360-4, 19/10961-4)
COSTA, S. O.; SOUZA, C. M.; LANZA, P. G.; SARTORI, J. O.; IGNACIO-SOUZA, L. M.; CANDREVA, T.; RODRIGUES, H. G.; TORSONI, A. S.; MILANSKI, M.; TORSONI, M. A.. Maternal high fat diet consumption reduces liver alpha7 nicotinic cholinergic receptor expression and impairs insulin signalling in the offspring. SCIENTIFIC REPORTS, v. 10, n. 1, . (16/23484-1, 13/07607-8)
DELLA-FELICE, FRANCO; BARTOLOMEU, ALOISIO DE ANDRADE; PILLI, RONALDO ALOISE. The phosphate ester group in secondary metabolites. NATURAL PRODUCT REPORTS, v. 39, n. 5, p. 42-pg., . (16/12541-4, 14/25474-8, 19/13104-5, 13/07607-8, 20/07991-6)
ROSA, LUCAS R. O.; SOARES, GABRIELA M.; SILVEIRA, LEONARDO R.; BOSCHERO, ANTONIO C.; BARBOSA-SAMPAIO, HELENA C. L.. ARHGAP21 as a master regulator of multiple cellular processes. Journal of Cellular Physiology, v. 233, n. 11, p. 8477-8481, . (12/14993-9, 13/07607-8, 15/12611-0)
DAMIAO, MARIANA C. F. C. B.; GALAVERNA, RENAN; KOZIKOWSKI, ALAN P.; EUBANKS, JAMES; PASTRE, JULIO C.. Telescoped continuous flow generation of a library of highly substituted 3-thio-1,2,4-triazoles. REACTION CHEMISTRY & ENGINEERING, v. 2, n. 6, p. 896-907, . (15/18572-6, 14/25770-6, 14/26378-2, 13/07607-8)
PAYOLLA, TANYARA B.; TEIXEIRA, CAIO J.; SATO, FABIO T.; MURATA, GILSON M.; ZONTA, GIZELA A.; SODRE, FRHANCIELLY S.; CAMPOS, CAROLINA V.; MESQUITA, FILIPHE N.; ANHE, GABRIEL F.; BORDIN, SILVANA. In Utero Dexamethasone Exposure Exacerbates Hepatic Steatosis in Rats That Consume Fructose During Adulthood. NUTRIENTS, v. 11, n. 9, . (13/07607-8, 14/08913-8, 15/25597-5)
BUSANELLO, ESTELA N. B.; MARQUES, ANA C.; LANDER, NOELIA; DE OLIVEIRA, DIOGO N.; CATHARINO, RODRIGO R.; OLIVEIRA, HELENA C. F.; VERCESI, ANIBAL E.. Pravastatin Chronic Treatment Sensitizes Hypercholesterolemic Mice Muscle to Mitochondrial Permeability Transition: Protection by Creatine or Coenzyme Q(10). FRONTIERS IN PHARMACOLOGY, v. 8, . (14/00084-2, 14/11261-2, 14/08995-4, 13/07607-8, 11/50400-0)
PILLI, RONALDO A.; DE ASSIS, FRANCISCO F.. Organic Synthesis: New Vistas in the Brazilian Landscape. Anais da Academia Brasileira de Ciências, v. 90, n. 1, 1, p. 895-941, . (13/07607-8, 16/12541-4, 16/08569-0, 17/06836-4)
DELLA-FELICE, FRANCO; PILLI, RONALDO A.; SAROTTI, ARIEL M.. Computer-Guided Total Synthesis of Natural Products. Recent Examples and Future Perspectives. Journal of the Brazilian Chemical Society, v. 29, n. 5, p. 1041-1075, . (14/25474-8, 16/12541-4, 13/07607-8)
SANTOS, ROBERTA DE SOUZA; CAMARGO, RAFAEL L.; VANZELA, EMERIELLE C.; BATISTA, THIAGO M.; MORATO, PRISCILA N.; LEITE, NAYARA C.; ROVANI, JULIANA C.; GARCIA-AREVALO, MARTA; CLEGG, DEBORAH J.; CARNEIRO, EVERARDO M.. Diet-induced glucose homeostasis dysregulation is enhanced by taurine supplementation in ovariectomized mice. Amino Acids, v. 50, n. 3-4, p. 469-477, . (13/07607-8)
GALAVERNA, RENAN; BREITKREITZ, MARCIA C.; PASTRE, JULIO C.. Conversion of D-Fructose to 5-(Hydroxymethyl)furfural: Evaluating Batch and Continuous Flow Conditions by Design of Experiments and In-Line FTIR Monitoring. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 6, n. 3, p. 4220-4230, . (14/25770-6, 16/05636-9, 06/57897-9, 14/26378-2, 13/07607-8)
MENDES, MARIA CAROLINA S.; PIMENTEL, GUSTAVO D.; COSTA, FELIPE O.; CARVALHEIRA, JOSE B. C.. Molecular and neuroendocrine mechanisms of cancer cachexia. Journal of Endocrinology, v. 226, n. 3, p. R29-R43, . (13/07607-8, 14/22347-5)
DE-LIMA-JUNIOR, JOSE C.; SOUZA, GABRIELA F.; MOURA-ASSIS, ALEXANDRE; GASPAR, RODRIGO S.; GASPAR, JOANA M.; ROCHA, ANDREA L.; FERRUCCI, DANILO L.; LIMA, TANES I.; VICTORIO, SHEILA C.; BONFANTE, IVAN L. P.; et al. Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency. EBIOMEDICINE, v. 39, p. 436-447, . (13/07607-8)
DE SOUZA, GABRIELA F. P.; NOVAES, LUIZ F. T.; AVILA, CAROLINA M.; NASCIMENTO, LUCAS F. R.; VELLOSO, LICIO A.; PILLI, RONALDO A.. (-)-Tarchonanthuslactone Exerts a Blood Glucose-Increasing Effect in Experimental Type 2 Diabetes Mellitus. Molecules, v. 20, n. 3, p. 5038-5049, . (12/09254-2, 10/08673-6, 13/07607-8)
PIROVANI, RODRIGO V.; BRITO, GILMAR A.; BARCELOS, ROSIMEIRE C.; PILLI, RONALDO A.. Enantioselective Total Synthesis of (+)-Lyngbyabellin M. MARINE DRUGS, v. 13, n. 6, p. 3309-3324, . (10/00336-0, 09/51602-5, 13/07607-8, 10/00219-4)
GARCIA-AREVALO, MARTA; LORZA-GIL, ESTELA; CARDOSO, LEANDRO; BATISTA, THIAGO MARTINS; ARAUJO, THIAGO REIS; FERREIRA RAMOS, LUIZ ALBERTO; AREAS, MIGUEL ARCANJO; NADAL, ANGEL; CARNEIRO, EVERARDO MAGALHAES; DAVEL, ANA PAULA. Ventricular Fibrosis and Coronary Remodeling Following Short-Term Exposure of Healthy and Malnourished Mice to Bisphenol A. FRONTIERS IN PHYSIOLOGY, v. 12, . (18/26080-4, 14/09532-8, 14/01717-9, 13/07607-8)
POVOA, VALERIA C. O.; DOS SANTOS, GIOVANNA J. V. P.; PICHETH, GUILHERME F.; JARA, CARLOS P.; DA SILVA, LAURA C. E.; DE ARAUJO, ELIANA P.; DE OLIVEIRA, MARCELO G.. Wound healing action of nitric oxide-releasing self-expandable collagen sponge. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, v. 14, n. 6, . (13/07607-8, 18/14142-5, 17/04615-0, 16/02414-5, 17/19253-7)
MONTEIRO, LAUAR DE BRITO; PRODONOFF, JULIANA SILVEIRA; DE AGUIAR, CRISTHIANE FAVERO; CORREA-DA-SILVA, FELIPE; CASTOLDI, ANGELA; BAKKER, NIKKI VAN TEIJLINGEN; DAVANZO, GUSTAVO GASTAO; CASTELUCCI, BIANCA; PEREIRA, JESSICA APARECIDA DA SILVA; CURTIS, JONATHAN; et al. Leptin Signaling Suppression in Macrophages Improves Immunometabolic Outcomes in Obesity. Diabetes, v. 71, n. 7, p. 16-pg., . (13/07607-8, 19/06372-3, 18/19338-5, 16/23328-0, 19/25973-8, 20/16030-0, 19/19435-3)
PRADO, THAIS P.; ZANCHETTA, FLAVIA CRISTINA; BARBIERI, BEATRIZ; APARECIDO, CAROLINE; LIMA, MARIA HELENA MELO; ARAUJO, ELIANA P.. Photobiomodulation with Blue Light on Wound Healing: A Scoping Review. LIFE-BASEL, v. 13, n. 2, p. 25-pg., . (21/00781-9, 13/07607-8)
LIMA, TANES I.; LAURILA, PIRKKA-PEKKA; WOHLWEND, MARTIN; MOREL, JEAN DAVID; GOEMINNE, LUDGER J. E.; LI, HAO; ROMANI, MARIO; LI, XIAOXU; OH, CHANG-MYUNG; PARK, DOHYUN; et al. Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging. Science Translational Medicine, v. 15, n. 696, p. 14-pg., . (19/11171-7, 13/07607-8, 16/23008-5, 19/22512-0)
VICENTE, JULIA MODESTO; LESCANO, CAROLINE HONAISER; BORDIN, SILVANA; MONICA, FABIOLA ZAKIA; GOBBI, GABRIELLA; ANHE, GABRIEL FORATO. Agomelatine inhibits platelet aggregation through melatonin receptor-dependent and independent mechanisms. Life Sciences, v. 328, p. 14-pg., . (19/03196-0, 13/07607-8, 19/19488-0, 20/13940-5)
SANTOS SILVA, BRUNA RAFAELA; JARA, CARLOS POBLETE; SIDARTA-OLIVEIRA, DAVI; VELLOSO, LICIO A.; VELANDER, WILLIAM H.; ARAUJO, ELIANA P.. Downregulation of the Protein C Signaling System Is Associated with COVID-19 Hypercoagulability-A Single-Cell Transcriptomics Analysis. Viruses-Basel, v. 14, n. 12, p. 16-pg., . (13/07607-8)
COSTA-PASCHOALINI, M.; BERNARDES, A. F.; BUZOLIN, M.; ZOLLNER, R. L.; MANSOUR, E.; VELLOSO, L. A.; YANG, A. C.. Successful Oral Desensitization in Sesame Allergy in an Adult Woman. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY, v. 29, n. 6, p. 3-pg., . (13/07607-8)
CARVALHO-ROMANO, LUIS F. R. S.; BONAFE, RAFAEL P.; PAIM, LAYDE R.; MARQUES, EDMILSON R.; VEGIAN, CAMILA F. L.; PIO-MAGALHAES, JOSE A.; MELLO, DANIEL S. S.; SCHREIBER, ROBERTO; SPOSITO, ANDREI C.; MATOS-SOUZA, JOSE R.; et al. Association of left ventricular strain and E/e' ratio with carotid wall layers. ATHEROSCLEROSIS, v. 310, p. 2-pg., . (13/07607-8)
SALERNO, ALESSANDRO G.; RENTZ, THIAGO; DORIGHELLO, GABRIEL G.; MARQUES, ANA CAROLINA; LORZA-GIL, ESTELA; WANSCHEL, AMARYLIS C. B. A.; DE MORAES, AUDREY; VERCESI, ANIBAL E.; OLIVEIRA, HELENA C. F.. Lack of mitochondrial NADP(H)-transhydrogenase expression in macrophages exacerbates atherosclerosis in hypercholesterolemic mice. Biochemical Journal, v. 476, p. 21-pg., . (11/15103-4, 11/15101-1, 13/05497-0, 11/50400-0, 17/02903-9, 13/07607-8, 17/17728-8)
LUBACZEUSKI, CAMILA; GONCALVES, LUCIANA MATEUS; VETTORAZZI, JEAN FRANCIESCO; KURAUTI, MIRIAN AYUMI; SANTOS-SILVA, JUNIA CAROLINA; BONFLEUR, MARIA LUCIA; BOSCHERO, ANTONIO CARLOS; COSTA-JUNIOR, JOSE MARIA; CARNEIRO, EVERARDO MAGALHAES. Vagotomy Reduces Insulin Clearance in Obese Mice Programmed by Low-Protein Diet in the Adolescence. NEURAL PLASTICITY, v. 2017, p. 7-pg., . (13/07607-8, 14/01717-9)
PARRAS SOUZA, ANELISE CRISTINA; SOUZA, CAMILLA MENDES; AMARA, CAMILA LIBARDI; LEMES, SIMONE FERREIRA; SANTUCCI, LETICIA FOGLIA; MILANSKI, MARCIANE; TORSONI, ADRIANA SOUZA; TORSONI, MARCIO ALBERTO. Short-Term High-Fat Diet Consumption Reduces Hypothalamic Expression of the Nicotinic Acetylcholine Receptor alpha 7 Subunit (alpha 7nAChR) and Affects the Anti-inflammatory Response in a Mouse Model of Sepsis. FRONTIERS IN IMMUNOLOGY, v. 10, . (13/07607-8, 16/23484-1)
QUARESMA, P. G. F.; WEISSMANN, L.; ZANOTTO, T. M.; SANTOS, A. C.; DE MATOS, A. H. B.; FURIGO, I. C.; SIMABUCO, F. M.; DONATO, JR., J.; BITTENCOURT, J. C.; LOPES-CENDES, I.; et al. Cdc2-like kinase 2 in the hypothalamus is necessary to maintain energy homeostasis. International Journal of Obesity, v. 41, n. 2, p. 268-278, . (15/00343-0, 13/07607-8, 12/10338-6)
CHAMPEAU, MATHILDE; POVOA, VALERIA; MILITAO, LUCAS; CABRINI, FLAVIA M.; PICHETH, GUILHERME F.; MENEAU, FLORIAN; JARA, CARLOS P.; DE ARAUJO, ELIANA P.; DE OLIVEIRA, MARCELO G.. Supramolecular poly(acrylic acid)/F127 hydrogel with hydration-controlled nitric oxide release for enhancing wound healing. Acta Biomaterialia, v. 74, p. 312-325, . (16/02414-5, 17/19253-7, 14/24955-2, 15/17515-9, 13/07607-8)
MARQUES, ANA C.; BUSANELLO, ESTELA N. B.; DE OLIVEIRA, DIOGO N.; CATHARINO, RODRIGO R.; OLIVEIRA, HELENA C. F.; VERCESI, ANIBAL E.. Coenzyme Q10 or Creatine Counteract Pravastatin-Induced Liver Redox Changes in Hypercholesterolemic Mice. FRONTIERS IN PHARMACOLOGY, v. 9, . (11/50400-0, 17/17728-8, 13/07607-8)
VERCESI, ANIBAL E.; CASTILHO, ROGER F.; KOWALTOWSKI, ALICIA J.; DE OLIVEIRA, HELENA C. F.; DE SOUZA-PINTO, NADJA C.; FIGUEIRA, TIAGO R.; BUSANELLO, ESTELA N. B.. Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition. Free Radical Biology and Medicine, v. 129, p. 1-24, . (17/17728-8, 11/50400-0, 06/59786-0, 14/11261-2, 13/07607-8)
DORIGHELLO, GABRIEL G.; INADA, NATALIA M.; PAIM, BRUNO A.; PARDO-ANDREU, GILBERTO L.; VERCESI, ANIBAL E.; OLIVEIRA, HELENA C. F.. Mangifera indica L. extract (Vimang (R)) reduces plasma and liver cholesterol and leucocyte oxidative stress in hypercholesterolemic LDL receptor deficient mice. Cell Biology International, v. 42, n. 6, SI, p. 747-753, . (13/07607-8, 11/50400-0)
LUBACZEUSKI, CAMILA; GONCALVES, LUCIANA MATEUS; VETTORAZZI, JEAN FRANCIESCO; KURAUTI, MIRIAN AYUMI; SANTOS-SILVA, JUNIA CAROLINA; BONFLEUR, MARIA LUCIA; BOSCHERO, ANTONIO CARLOS; COSTA-JUNIOR, JOSE MARIA; CARNEIRO, EVERARDO MAGALHAES. Vagotomy Reduces Insulin Clearance in Obese Mice Programmed by Low-Protein Diet in the Adolescence. NEURAL PLASTICITY, . (14/01717-9, 13/07607-8)
PASCOAL, LIVIA B.; BOMBASSARO, BRUNA; RAMALHO, ALBINA F.; COOPE, ANDRESSA; MOURA, RODRIGO F.; CORREA-DA-SILVA, FELIPE; IGNACIO-SOUZA, LETICIA; RAZOLLI, DANIELA; DE OLIVEIRA, DIOGO; CATHARINO, RODRIGO; et al. Resolvin RvD2 reduces hypothalamic inflammation and rescues mice from diet-induced obesity. JOURNAL OF NEUROINFLAMMATION, v. 14, . (13/07607-8)
HADDAD-TOVOLLI, ROBERTA; DRAGANO, NATHALIA R. V.; RAMALHO, ALBINA F. S.; VELLOSO, LICIO A.. Development and Function of the Blood-Brain Barrier in the Context of Metabolic Control. FRONTIERS IN NEUROSCIENCE, v. 11, . (15/50278-0, 15/02913-9, 14/26942-5, 16/01868-2, 13/07607-8)
SILVEIRA, ANDRE C.; FERNANDES, TIAGO; SOCI, URSULA P. R.; GOMES, JOAO L. P.; BARRETTI, DIEGO L.; MOTA, GLORIA G. F.; NEGRAO, CARLOS EDUARDO; OLIVEIRA, EDILAMAR M.. Exercise Training Restores Cardiac MicroRNA-1 and MicroRNA-29c to Nonpathological Levels in Obese Rats. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, . (10/50048-1, 13/07607-8, 09/18370-3)
CARNEIRO, VANIA M. T.; TRIVELLA, DANIELA B. B.; SCORSATO, VALERIA; BERALDO, VIVIANE L.; DIAS, MARIANA P.; SOBREIRA, TIAGO J. P.; APARICIO, RICARDO; PILLI, RONALDO A.. Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 97, p. 42-54, . (11/00457-5, 10/17544-5, 09/51602-5, 13/07607-8)
WEISSMANN, LAIS; QUARESMA, PAULA G. F.; SANTOS, ANDRESSA C.; DE MATOS, ALEXANDRE H. B.; PASCOAL, VINICIUS D'AVILA BITTENCOURT; ZANOTTO, TAMIRES M.; CASTRO, GISELE; GUADAGNINI, DIOZE; DA SILVA, JOELCIMAR MARTINS; VELLOSO, LICIO A.; et al. IKK epsilon Is Key to Induction of Insulin Resistance in the Hypothalamus, and Its Inhibition Reverses Obesity. Diabetes, v. 63, n. 10, p. 3334-3345, . (10/52068-0, 13/07607-8, 12/10338-6)
NOVAES, LUIZ F. T.; SAROTTI, ARIEL M.; PILLI, RONALDO A.. Total Synthesis and Tentative Structural Elucidation of Cryptomoscatone E3: Interplay of Experimental and Computational Studies. Journal of Organic Chemistry, v. 80, n. 24, p. 12027-12037, . (09/51602-5, 13/07607-8)
QUARESMA, P. G. F.; REENCOBER, N.; ZANOTTO, T. M.; SANTOS, A. C.; WEISSMANN, L.; DE MATOS, A. H. B.; LOPES-CENDES, I.; FOLLI, F.; SAAD, M. J. A.; PRADA, P. O.. Pioglitazone treatment increases food intake and decreases energy expenditure partially via hypothalamic adiponectin/adipoR1/AMPK pathway. International Journal of Obesity, v. 40, n. 1, p. 138-146, . (13/07607-8, 12/10338-6)
CONDES AREIAS, MARIA FERNANDA; PRADA, PATRICIA OLIVEIRA. Mechanisms of insulin resistance in the amygdala: Influences on food intake. Behavioural Brain Research, v. 282, p. 209-217, . (13/07607-8, 12/10338-6)
NOGUEIRA, GUILHERME; SOLON, CARINA; CARRARO, RODRIGO S.; ENGEL, DAIANE F.; RAMALHO, ALBINA F.; SIDARTA-OLIVEIRA, DAVI; GASPAR, RODRIGO S.; BOMBASSARO, BRUNA; VASQUES, ANA C.; GELONEZE, BRUNO; et al. Interleukin-17 acts in the hypothalamus reducing food intake. BRAIN BEHAVIOR AND IMMUNITY, v. 87, p. 272-285, . (13/07607-8)
MENDES, NATALIA F.; JARA, CARLOS P.; MANSOUR, ELI; ARAUJO, ELIANA P.; VELLOSO, LICIO A.. Asthma and COVID-19: a systematic review. ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, v. 17, n. 1, . (13/07607-8, 16/17810-3)
WANSCHEL, AMARYLIS C. B. A.; GUIZONI, DANIELE M.; LORZA-GIL, ESTELA; SALERNO, ALESSANDRO G.; PAIVA, ADRIENE A.; DORIGHELLO, GABRIEL G.; DAVEL, ANA PAULA; BALKAN, WAYNE; HARE, JOSHUA M.; OLIVEIRA, HELENA C. F.. The Presence of Cholesteryl Ester Transfer Protein (CETP) in Endothelial Cells Generates Vascular Oxidative Stress and Endothelial Dysfunction. BIOMOLECULES, v. 11, n. 1, . (16/01746-4, 13/05497-0, 11/50400-0, 13/07607-8, 13/09347-3, 16/01044-0)
DELAFIORI, JEANY; LIMA, ESTELA DE OLIVEIRA; DABAJA, MOHAMED ZIAD; DIAS-AUDIBERT, FLAVIA LUISA; DE OLIVEIRA, DIOGO NOIN; RODRIGUES MELO, CARLOS FERNANDO ODIR; MORISHITA, KAREN NODA; SALES, GEOVANA MANZAN; TASCA GOIS RUIZ, ANA LUCIA; DA SILVA, GISELE GOULART; et al. Molecular signatures associated with prostate cancer cell line (PC-3) exposure to inactivated Zika virus. SCIENTIFIC REPORTS, v. 9, . (13/07607-8, 16/17066-2)
DELLA-FELICE, FRANCO; DE ASSIS, FRANCISCO F.; SAROTTI, ARIEL M.; PILLI, RONALDO A.. Palladium-Catalyzed Formation of Substituted Tetrahydropyrans: Mechanistic Insights and Structural Revision of Natural Products. SYNTHESIS-STUTTGART, v. 51, n. 7, p. 1545-1560, . (13/07607-8, 16/12541-4, 14/25474-8)
GALAVERNA, RENAN; RIBESSI, RAFAEL L.; ROHWEDDER, JARBAS J. R.; PASTRE, JULIO C.. Coupling Continuous Flow Microreactors to MicroNIR Spectroscopy: Ultracompact Device for Facile In-Line Reaction Monitoring. ORGANIC PROCESS RESEARCH & DEVELOPMENT, v. 22, n. 7, p. 780-788, . (14/50951-4, 14/26378-2, 14/25770-6, 13/07607-8)
SCHREIBER, ROBERTO; SOUZA, CRISTIANE M.; PAIM, LAYDE R.; DE ROSSI, GUILHERME; MATOS-SOUZA, JOSE R.; COSTA E SILVA, ANSELMO DE A.; FARIA, FERNANDO R.; AZEVEDO, ELIZA R.; ALONSO, KARINA C.; SPOSITO, ANDREI C.; et al. Impact of Regular Physical Activity on Adipocytokines and Cardiovascular Characteristics in Spinal Cord-Injured Subjects. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, v. 99, n. 8, p. 1561-1567, . (13/07607-8)
DA CUNHA, LORENA PIRES; SILVEIRA, MARINA NOGUEIRA; SANTOS MENDES, MARIA CAROLINA; COSTA, FELIPE OSORIO; MACEDO, LIGIA TRALDI; DE SIQUEIRA, NADIA SCLEARUC; CAMPELLO CARVALHEIRA, JOSE BARRETO. Sarcopenia as an independent prognostic factor in patients with metastatic colorectal cancer: A retrospective evaluation. CLINICAL NUTRITION ESPEN, v. 32, p. 107-112, . (10/19503-4, 13/07607-8)
PAIM, LAYDE R.; SCHREIBER, ROBERTO; DE ROSSI, GUILHERME; MATOS-SOUZA, JOSE R.; COSTA E SILVA, ANSELMO DE A.; CALEGARI, DECIO ROBERTO; CHENG, SUSAN; MARQUES, FRANCINE Z.; SPOSITO, ANDREI C.; GORLA, JOSE I.; et al. Circulating microRNAs, Vascular Risk, and Physical Activity in Spinal Cord-Injured Subjects. JOURNAL OF NEUROTRAUMA, v. 36, n. 6, . (13/07607-8)
DATILO, MARCELLA NEVES; SANT'ANA, MARCELLA RAMOS; FORMIGARI, GUILHERME PEDRON; RODRIGUES, PATRICIA BRITO; DE MOURA, LEANDRO PEREIRA; RAMOS DA SILVA, ADELINO SANCHEZ; ROPELLE, EDUARDO ROCHETE; PAULI, JOSE RODRIGO; CINTRA, DENNYS ESPER. Omega-3 from Flaxseed Oil Protects Obese Mice Against Diabetic Retinopathy Through GPR120 Receptor. SCIENTIFIC REPORTS, v. 8, . (13/07607-8, 12/07129-6)
DE ARAUJO, THIAGO MATOS; RAZOLLI, DANIELA S.; CORREA-DA-SILVA, FELIPE; DE LIMA-JUNIOR, JOSE C.; GASPAR, RODRIGO S.; SIDARTA-OLIVEIRA, DAVI; VICTORIO, SHEILA C.; DONATO, JR., JOSE; KIM, YOUNG-BUM; VELLOSO, LICIO A.. The partial inhibition of hypothalamic IRX3 exacerbates obesity. EBIOMEDICINE, v. 39, p. 448-460, . (17/02983-2, 13/07607-8)
KURAUTI, MIRIAN A.; FREITAS-DIAS, RICARDO; FERREIRA, SANDRA M.; VETTORAZZI, JEAN F.; NARDELLI, TARLLIZA R.; ARAUJO, HYGOR N.; SANTOS, GUSTAVO J.; CARNEIRO, EVERARDO M.; BOSCHERO, ANTONIO C.; REZENDE, LUIZ F.; et al. Acute Exercise Improves Insulin Clearance and Increases the Expression of Insulin-Degrading Enzyme in the Liver and Skeletal Muscle of Swiss Mice. PLoS One, v. 11, n. 7, . (13/07607-8, 14/24719-7)
LEITE, NAYARA CARVALHO; DE PAULA, FLAVIA; BORCK, PATRICIA CRISTINE; VETTORAZZI, JEAN FRANCIESCO; SOUTO BRANCO, RENATO CHAVES; LUBACZEUSKI, CAMILA; BOSCHERO, ANTONIO CARLOS; ZOPPI, CLAUDIO CESAR; CARNEIRO, EVERARDO MAGALHAES. Protein malnutrition potentiates the amplifying pathway of insulin secretion in adult obese mice. SCIENTIFIC REPORTS, v. 6, . (11/19536-2, 13/07607-8, 11/09012-6)
ZAMBOM DE SOUZA, ALESSANDRA ZANIN; ZAMBOM, ADRIANO ZANIN; ABBOUD, KAHLILE YOUSSEF; REIS, SABRINA KAREN; TANNIHAO, FABIANA; GUADAGNINI, DIOZE; SAAD, MARIO J. A.; PRADA, PATRICIA OLIVEIRA. Oral supplementation with L-glutamine alters gut microbiota of obese and overweight adults: A pilot study. NUTRITION, v. 31, n. 6, p. 884-889, . (13/07607-8, 12/10338-6)
RAZOLLI, DANIELA S.; DE ARAUJO, THIAGO M.; SANT'ANA, MARCELLA R.; KIRWAN, PETER; CINTRA, DENNYS E.; MERKLE, FLORIAN T.; VELLOSO, LICIO A.. Proopiomelanocortin Processing in the Hypothalamus Is Directly Regulated by Saturated Fat: Implications for the Development of Obesity. Neuroendocrinology, v. 110, n. 1-2, p. 92-104, . (13/07607-8)
GUIZONI, DANIELE M.; VETTORAZZI, JEAN F.; CARNEIRO, EVERARDO M.; DAVEL, ANA PAULA. Modulation of endothelium-derived nitric oxide production and activity by taurine and taurine-conjugated bile acids. NITRIC OXIDE-BIOLOGY AND CHEMISTRY, v. 94, p. 48-53, . (14/01717-9, 13/07607-8, 16/14461-8)
E-LACERDA, RODRIGO RODRIGUES; TEIXEIRA, CAIO JORDAO; BORDIN, SILVANA; ANTUNES, EDSON; ANHE, GABRIEL FORATO. Maternal Obesity in Mice Exacerbates the Allergic Inflammatory Response in the Airways of Male Offspring. NUTRIENTS, v. 11, n. 12, . (16/22722-6, 17/20742-2, 17/15175-1, 13/07607-8, 15/18997-7)
SALERNO, ALESSANDRO G.; RENTZ, THIAGO; DORIGHELLO, GABRIEL G.; MARQUES, ANA CAROLINA; LORZA-GIL, ESTELA; WANSCHEL, AMARYLIS C. B. A.; DE MORAES, AUDREY; VERCESI, ANIBAL E.; OLIVEIRA, HELENA C. F.. Lack of mitochondrial NADP(H)-transhydrogenase expression in macrophages exacerbates atherosclerosis in hypercholesterolemic mice. Biochemical Journal, v. 476, n. 24, p. 3769-3789, . (11/15101-1, 11/15103-4, 11/50400-0, 13/05497-0, 17/17728-8, 13/07607-8, 17/02903-9)
CARVALHO-ROMANO, LUIS F. R. S.; BONAFE, RAFAEL P.; PAIM, LAYDE R.; MARQUES, EDMILSON R.; VEGIAN, CAMILA F. L.; PIO-MAGALHAES, JOSE A.; MELLO, DANIEL S. S.; DE ROSSI, GUILHERME; COELHO-FILHO, OTAVIO R.; SCHREIBER, ROBERTO; et al. Association of carotid wall layers with atherosclerotic plaques and cardiac hypertrophy in hypertensive subjects. JOURNAL OF HUMAN HYPERTENSION, . (13/07607-8)
MENDES, NATALIA F.; VELLOSO, LICIO A.. Perivascular macrophages in high-fat diet-induced hypothalamic inflammation. JOURNAL OF NEUROINFLAMMATION, v. 19, n. 1, p. 10-pg., . (13/07607-8)
DORIGHELLO, GABRIEL G.; ROVANI, JULIANA C.; PAIM, BRUNO A.; RENTZ, THIAGO; ASSIS, LEANDRO H. P.; VERCESI, ANIBAL E.; OLIVEIRA, HELENA C. F.. Mild Mitochondrial Uncoupling Decreases Experimental Atherosclerosis, A Proof of Concept. JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, v. 29, n. 6, p. 14-pg., . (17/17728-8, 13/07607-8, 17/02903-9, 14/02819-0, 17/03402-3)
DELLA-FELICE, FRANCO; SAROTTI, ARIEL M.; KRISCHE, MICHAEL J.; PILLI, RONALDO A.. Total Synthesis and Structural Validation of Phosdiecin A via Asymmetric Alcohol-Mediated Carbonyl Reductive Coupling. Journal of the American Chemical Society, v. 141, n. 35, p. 13778-13782, . (17/18487-4, 16/12541-4, 13/07607-8, 14/25474-8)
DE ARAUJO, THIAGO MATOS; VELLOSO, LICIO A.. Hypothalamic IRX3: A New Player in the Development of Obesity. TRENDS IN ENDOCRINOLOGY AND METABOLISM, v. 31, n. 5, p. 368-377, . (13/07607-8)
VICENTE, JULIA MODESTO; SANTOS-SILVA, JUNIA CAROLINA; TEIXEIRA, CAIO JORDAO; DE SOUZA, DAILSON NOGUEIRA; VETTORAZZI, JEAN FRANCIESCO; FURTUOSO, FABIOLA SALES; ADABO, ISABEL GOUVEIA; SATO, FABIO TAKEO; RAMIREZ VINOLO, MARCO AURELIO; CARNEIRO, EVERARDO MAGALHAES; et al. Long-term increase of insulin secretion in mice subjected to pregnancy and lactation. ENDOCRINE CONNECTIONS, v. 9, n. 4, p. 299-308, . (13/07607-8, 15/12680-1, 17/11138-4)
DAMIAO, MARIANA C. F. C. B.; MARCON, HENRIQUE M.; PASTRE, JULIO CEZAR. Continuous flow synthesis of the URAT1 inhibitor lesinurad. REACTION CHEMISTRY & ENGINEERING, v. 5, n. 5, p. 865-872, . (14/25770-6, 14/26378-2, 15/18572-6, 13/07607-8, 18/25233-1)
BRAGA, CAROLYNE B.; KIDO, LARISSA A.; LIMA, ELLEN N.; LAMAS, CELINA A.; CAGNON, VALERIA H. A.; ORNELAS, CATIA; PILLI, RONALDO A.. Enhancing the Anticancer Activity and Selectivity of Goniothalamin Using pH-Sensitive Acetalated Dextran (Ac-Dex) Nanoparticles: A Promising Platform for Delivery of Natural Compounds. ACS BIOMATERIALS SCIENCE & ENGINEERING, v. 6, n. 5, SI, p. 2929-2942, . (18/02093-0, 17/06146-8, 19/13104-5, 13/07607-8)
ALMEIDA, LORENA DE SOUZA; TEIXEIRA, CAIO JORDAO; CAMPOS, CAROLINA VIEIRA; CASALOTI, LAIS GUADALUPE; SODRE, FRHANCIELLY SHIRLEY; CAPETINI, VINICIUS COOPER; AMARAL, ANDRESSA GODOY; PAYOLLA, TANYARA BALIANI; PANTALEAO, LUCAS CARMINATTI; ANHE, GABRIEL FORATO; et al. Low Birth Weight Intensifies Changes in Markers of Hepatocarcinogenesis Induced by Fructose Consumption in Rats. METABOLITES, v. 12, n. 10, p. 15-pg., . (13/07607-8, 20/13940-5, 19/03196-0, 20/06397-3)
CORREA, RENAN OLIVEIRA; CASTRO, POLLYANA RIBEIRO; MOSER, RENE; FERREIRA, CAROLINE MARCANTONIO; QUESNIAUX, VALERIE F. J.; RAMIREZ VINOLO, MARCO AURELIO; RYFFEL, BERNHARD. Butyrate: Connecting the gut-lung axis to the management of pulmonary disorders. FRONTIERS IN NUTRITION, v. 9, p. 16-pg., . (13/07607-8, 18/15313-8)
BOBBO, VANESSA C.; ENGEL, DAIANE F.; JARA, CARLOS POBLETE; MENDES, NATALIA F.; HADDAD-TOVOLLI, ROBERTA; PRADO, THAIS P.; SIDARTA-OLIVEIRA, DAVI; MORARI, JOSEANE; VELLOSO, LICIO A.; ARAUJO, ELIANA P.. Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis. JOURNAL OF NEUROINFLAMMATION, v. 18, n. 1, . (13/07607-8)
VERONESI, VANESSA BARBOSA; PIOLI, MARIANA RODRIGUES; DE SOUZA, DAILSON NOGUEIRA; TEIXEIRA, CAIO JORDAO; MURATA, GILSON MASAHIRO; SANTOS-SILVA, JUNIA CAROLINA; HECHT, FERNANDA BALLERINI; VICENTE, JULIA MODESTO; BORDIN, SILVANA; ANHE, GABRIEL FORATO. Agomelatine reduces circulating triacylglycerides and hepatic steatosis in fructose-treated rats. BIOMEDICINE & PHARMACOTHERAPY, v. 141, . (16/13138-9, 13/07607-8, 15/23285-6, 20/06397-3, 17/20742-2, 19/03196-0)
MOURA-ASSIS, ALEXANDRE; NOGUEIRA, PEDRO A. S.; DE-LIMA-JUNIOR, JOSE C.; SIMABUCO, FERNANDO M.; GASPAR, JOANA M.; DONATO JR, JOSE; VELLOSO, LICIO A.. TLR4-interactor with leucine-rich repeats (TRIL) is involved in diet-induced hypothalamic inflammation. SCIENTIFIC REPORTS, v. 11, n. 1, . (18/14818-9, 17/02983-2, 13/07607-8)
VICTORIO, JAMAIRA A.; GUIZONI, DANIELE M.; FREITAS, ISRAELLE N.; ARAUJO, THIAGO R.; DAVEL, ANA P.. Effects of High-Fat and High-Fat/High-Sucrose Diet-Induced Obesity on PVAT Modulation of Vascular Function in Male and Female Mice. FRONTIERS IN PHARMACOLOGY, v. 12, . (18/16505-8, 13/07607-8, 18/00543-8)
FERNANDES LOPES, PRISCILLA KARLA; ENGEL, DAIANE FATIMA; BERTOLINI, NATALIA OLIVEIRA; DE AZEVEDO MARTINS, MOISES SILVESTRE; PEREIRA, CHRYSTIAN ARAUJO; VELLOSO, LICIO AUGUSTO; THOMASI, SERGIO SCHERRER; DE MOURA, RODRIGO FERREIRA. Behavioral, neuroplasticity and metabolic effects of 7,8-dihydroxy-4-methylcoumarin associated with physical activity in mice. METABOLIC BRAIN DISEASE, v. 36, n. 8, . (13/07607-8, 14/50938-8)
SOARES, G. M.; BALBO, S. L.; BRONCZEK, G. A.; MARMENTINI, C.; ZANGEROLAMO, L.; VELLOSO, L. A.; CARNEIRO, E. M.. In vivo and in vitro effect of vertical sleeve gastrectomy upon glucose-insulin homeostasis and beta cell function and survival. Diabetologia, v. 64, n. SUPPL 1, p. 2-pg., . (19/00728-0, 13/07607-8)
BRAGA, RENATA R.; CRISOL, BARBARA M.; BRICOLA, RAFAEL S.; SANT'ANA, MARCELLA R.; NAKANDAKARI, SUSANA C. B. R.; COSTA, SULEYMA O.; PRADA, PATRICIA O.; DA SILVA, ADELINO S. R.; MOURA, LEANDRO P.; PAULI, JOSE R.; et al. Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPRmt in the hypothalamus of mice. SCIENTIFIC REPORTS, v. 11, n. 1, . (17/18695-6, 13/07607-8, 18/07634-9, 19/21709-4)
RENTZ, THIAGO; WANSCHEL, AMARYLIS C. B. A.; DE CARVALHO MOI, LEONARDO; LORZA-GIL, ESTELA; DE SOUZA, JANE C.; DOS SANTOS, RENATA R.; OLIVEIRA, HELENA C. F.. The Anti-atherogenic Role of Exercise Is Associated With the Attenuation of Bone Marrow-Derived Macrophage Activation and Migration in Hypercholesterolemic Mice. FRONTIERS IN PHYSIOLOGY, v. 11, . (17/17728-8, 13/07607-8)
LIMA-SILVA, LINCON FELIPE; LEE, JENNIFER; MORAES-VIEIRA, PEDRO M.. Soluble Carrier Transporters and Mitochondria in the Immunometabolic Regulation of Macrophages. Antioxidants & Redox Signaling, . (13/07607-8, 19/19435-3, 19/25973-8, 15/15626-8)
PRADO, T. P.; MORARI, J.; ARAUJO, E. P.. Molecular and morphological alterations in uninjured skin of streptozotocin-induced diabetic mice. Brazilian Journal of Medical and Biological Research, v. 56, n. 1, p. 11-pg., . (13/07607-8)
MOREIRA, KARINA GOMES; DO PRADO, THAIS PAULINO; MENDES, NATALIA FERREIRA; BEZERRA, RENAN DE MEDEIROS; JARA, CARLOS POBLETE; MELO LIMA, MARIA HELENA; DE ARAUJO, ELIANA PEREIRA. ccelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen depositio. PLoS One, v. 16, n. 10, . (13/07607-8)
BRAGA, CAROLYNE B.; PILLI, RONALDO A.; ORNELAS, CATIA; WECK, MARCUS. ear-Infrared Fluorescent Micelles from Poly(norbornene) Brush Triblock Copolymers for Nanotheranostic. Biomacromolecules, v. 22, n. 12, p. 5290-5306, . (13/07607-8, 19/13104-5, 14/50906-9, 18/24020-4, 17/06146-8)
ZANESCO, ARIANE MARIA; MENDES, NATALIA F.; ENGEL, DAIANE F.; GASPAR, RODRIGO S.; SIDARTA-OLIVEIRA, DAVI; DONATO, JOSE; VELLOSO, LICIO A.. Hypothalamic CREB Regulates the Expression of Pomc-Processing Enzyme Pcsk2. CELLS, v. 11, n. 13, p. 20-pg., . (13/07607-8, 19/00330-7)
ALBERICI, LUCIANE C.; OLIVEIRA, HELENA C. F.. Mitochondrial Adaptive Responses to Hypertriglyceridemia and Bioactive Lipids. Antioxidants & Redox Signaling, v. 36, n. 13, p. 16-pg., . (13/07607-8, 17/17728-8, 18/10089-2)
BRONCZEK, GABRIELA ALVES; SOARES, GABRIELA MOREIRA; MARMENTINI, CARINE; BOSCHERO, ANTONIO CARLOS; COSTA-JUNIOR, JOSE MARIA. Resistance Training Improves Beta Cell Glucose Sensing and Survival in Diabetic Models. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 23, n. 16, p. 17-pg., . (13/07607-8, 21/04664-7, 18/15032-9, 15/12611-0, 16/17102-9)
SOUZA, STEPHAN P. M.; FRASSON, FERNANDA C.; TAKAHASHI, MARIA EMILIA S.; DUARTE, GISLAINE B. O.; CASTRO, VANIA P.; PERICOLE, FERNANDO V.; VELLOSO, LICIO A.; DE SOUZA, CARMINO A.; LORAND-METZE, IRENE; SANTOS, ALLAN O.; et al. Head-to-head comparison of [Ga-68]Ga-PSMA-11 and [F-18]FDG PET/CT in multiple myeloma. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, v. 50, n. 8, p. 9-pg., . (13/07607-8, 21/03421-3, 18/00654-4)
HADDAD TOVOLLI, ROBERT; MORARI, JOSEANE; BARBIZAN, ROBERTA; BOBBO, VANESSA C.; S. CARRARO, RODRIGO; SOLON, CARINA; DRAGANO, NATHALIA R.; TORSONI, MARCIO A.; P. ARAUJO, ELIANA; VELLOSO, LICIO A.. Maternal obesity damages the median eminence blood-brain barrier structure and function in the progeny: the beneficial impact of cross-fostering by lean mothers. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, v. 324, n. 2, p. 13-pg., . (15/02913-9, 13/07607-8)
GOES-SANTOS, BEATRIZ R.; RONDON, EDUARDO; FONSECA, GUILHERME W. P.; SALES, ALLAN R. K.; SANTOS, MARCELO R.; ANTUNES-CORREA, LIGIA M.; UENO-PARDI, LINDA M.; OLIVEIRA, PATRICIA; TREVIZAN, PATRICIA F.; FRANCO, FABIO G. MELLO; et al. Physical capacity increase in patients with heart failure is associated with improvement in muscle sympathetic nerve activity. INTERNATIONAL JOURNAL OF CARDIOLOGY, v. 378, p. 7-pg., . (13/07607-8)
MONFORT-PIRES, MILENA; REGENI-SILVA, GIULIANNA; DADSON, PRINCE; NOGUEIRA, GUILHERME A.; U-DIN, MUEEZ; FERREIRA, SANDRA R. G.; SAPIENZA, MARCELO TATIT; VIRTANEN, KIRSI A.; VELLOSO, LICIO A.. Brown fat triglyceride content is associated with cardiovascular risk markers in adults from a tropical region. FRONTIERS IN ENDOCRINOLOGY, v. 13, p. 13-pg., . (17/22586-8, 19/02055-3, 13/07607-8, 18/05479-6, 16/10616-7)
TEIXEIRA, CAIO JORDAO; SANTOS-SILVA, JUNIA CAROLINA; DE SOUZA, DAILSON NOGUEIRA; RAFACHO, ALEX; ANHE, GABRIEL FORATO; BORDIN, SILVANA. Dexamethasone during pregnancy impairs maternal pancreatic beta-cell renewal during lactation. ENDOCRINE CONNECTIONS, v. 8, n. 2, p. 12-pg., . (13/07607-8)
DORIGHELLO, GABRIEL G.; INADA, NATALIA M.; PAIM, BRUNO A.; PARDO-ANDREU, GILBERTO L.; VERCESI, ANIBAL E.; OLIVEIRA, HELENA C. F.. Mangifera indica L. extract (Vimang (R)) reduces plasma and liver cholesterol and leucocyte oxidative stress in hypercholesterolemic LDL receptor deficient mice. Cell Biology International, v. 42, n. 6, p. 7-pg., . (13/07607-8, 11/50400-0)
DORIGHELLO, GABRIEL G.; PAIM, BRUNO A.; LEITE, ANA CATARINA R.; VERCESI, ANIBAL E.; OLIVEIRA, HELENA C. F.. Spontaneous experimental atherosclerosis in hypercholesterolemic mice advances with ageing and correlates with mitochondrial reactive oxygen species. Experimental Gerontology, v. 109, p. 4-pg., . (13/07607-8, 11/50400-0)
OLIVEIRA, HELENA C. F.; RAPOSO, HELENA F.; JIANG, XC. Cholesteryl Ester Transfer Protein and Lipid Metabolism and Cardiovascular Diseases. LIPID TRANSFER IN LIPOPROTEIN METABOLISM AND CARDIOVASCULAR DISEASE, v. 1276, p. 11-pg., . (13/07607-8, 17/17728-8, 15/17555-0)
SANTOS, ROBERTA S.; BATISTA, THIAGO M.; CAMARGO, RAFAEL L.; MORATO, PRISCILA N.; BORCK, PATRICIA C.; LEITE, NAYARA C.; KURAUTI, MIRIAN A.; WANSCHEL, AMARYLIS C. B. A.; NADAL, ANGEL; CLEGG, DEBORAH J.; et al. Lacking of estradiol reduces insulin exocytosis from pancreatic beta-cells and increases hepatic insulin degradation. Steroids, v. 114, p. 9-pg., . (13/07607-8, 15/05801-7)
PAIVA, ADRIENE A.; RAPOSO, HELENA F.; WANSCHEL, AMARYLIS C. B. A.; NARDELLI, TARLLIZA R.; OLIVEIRA, HELENA C. F.. Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, v. 2017, p. 18-pg., . (13/07607-8, 11/50400-0)
VICENTE, JULIA MODESTO; SANTOS-SILVA, JUNIA CAROLINA; TEIXEIRA, CAIO JORDAO; DE SOUZA, DAILSON NOGUEIRA; VETTORAZZI, JEAN FRANCIESCO; FURTUOSO, FABIOLA SALES; ADABO, ISABEL GOUVEIA; SATO, FABIO TAKEO; RAMIREZ VINOLO, MARCO AURELIO; CARNEIRO, EVERARDO MAGALHAES; et al. Long-term increase of insulin secretion in mice subjected to pregnancy and lactation. ENDOCRINE CONNECTIONS, v. 9, n. 4, p. 10-pg., . (15/12680-1, 13/07607-8, 17/11138-4)
BRAGA, CAROLYNE B.; KIDO, LARISSA A.; LIMA, ELLEN N.; LAMAS, CELINA A.; CAGNON, VALERIA H. A.; ORNELAS, CATIA; PILLI, RONALDO A.. Enhancing the Anticancer Activity and Selectivity of Goniothalamin Using pH-Sensitive Acetalated Dextran (Ac-Dex) Nanoparticles: A Promising Platform for Delivery of Natural Compounds. ACS BIOMATERIALS SCIENCE & ENGINEERING, v. 6, n. 5, p. 14-pg., . (18/02093-0, 17/06146-8, 13/07607-8, 19/13104-5)
SILVEIRA, ANDRE C.; FERNANDES, TIAGO; SOCI, URSULA P. R.; GOMES, JOAO L. P.; BARRETTI, DIEGO L.; MOTA, GLORIA G. F.; NEGRAO, CARLOS EDUARDO; OLIVEIRA, EDILAMAR M.. Exercise Training Restores Cardiac MicroRNA-1 and MicroRNA-29c to Nonpathological Levels in Obese Rats (vol 2017, 1549014, 2017). OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, v. 2018, p. 1-pg., . (13/07607-8, 09/18370-3, 10/50048-1)
MENDES, NATALIA F.; JARA, CARLOS P.; MANSOUR, ELI; ARAUJO, ELIANA P.; VELLOSO, LICIO A.. Asthma and COVID-19: a systematic review. ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, v. 17, n. 1, p. 12-pg., . (13/07607-8, 16/17810-3)
SILVEIRA, ANDRE C.; FERNANDES, TIAGO; SOCI, URSULA P. R.; GOMES, JOAO L. P.; BARRETTI, DIEGO L.; MOTA, GLORIA G. F.; NEGRAO, CARLOS EDUARDO; OLIVEIRA, EDILAMAR M.. Exercise Training Restores Cardiac MicroRNA-1 and MicroRNA-29c to Nonpathological Levels in Obese Rats. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, v. 2017, p. 12-pg., . (13/07607-8, 09/18370-3, 10/50048-1)
MARMENTINI, CARINE; SOARES, GABRIELA M.; BRONCZEK, GABRIELA A.; PIOVAN, SILVANO; MAREZE-COSTA, CECILIA E.; CARNEIRO, EVERARDO M.; BOSCHERO, ANTONIO C.; KURAUTI, MIRIAN A.. Aging Reduces Insulin Clearance in Mice. FRONTIERS IN ENDOCRINOLOGY, v. 12, . (15/12611-0, 18/24368-0, 13/07607-8, 17/06475-1)
HECHT, FERNANDA BALLERINI; TEIXEIRA, CAIO JORDAO; DE SOUZA, DAILSON NOGUEIRA; NUNES MESQUITA, FILIPHE DE PAULA; DO VAL ROSO, RYANA ELYZABETH; SODRE, FRHANCIELLY SHIRLEY; VERONESI, VANESSA BARBOSA; DA ROCHA, DEBORAH FABIANA; DANTAS DE MENEZES, YAN GUIDA; PIOLI, MARIANA RODRIGUES; et al. Antenatal corticosteroid therapy modulates hepatic AMPK phosphorylation and maternal lipid metabolism in early lactating rats. BIOMEDICINE & PHARMACOTHERAPY, v. 144, . (19/03196-0, 13/07607-8, 20/09717-9, 16/13138-9, 20/06397-3)
BATISTA, ELLENCRISTINA SILVA; DA SILVA RIOS, THAIANE; MUNOZ, VITOR ROSETTO; JESUS, JOYCE SANTOS; VASCONCELOS, MARCEL MONTEIRO; DA CUNHA, DIOGO THIMOTEO; MARQUES-ROCHA, JOSE LUIS; NAKANDAKARI, SUSANA CASTELO BRANCO RAMOS; LARA, ROBERTA; DA SILVA, ADELINO SANCHEZ RAMOS; et al. Omega-3 mechanism of action in inflammation and endoplasmic reticulum stress in mononuclear cells from overweight non-alcoholic fatty liver disease participants: study protocol for the ``Brazilian Omega Study{''} (BROS)-a randomized controlled trial. Trials, v. 22, n. 1, . (12/07129-6, 13/07607-8)
CARVALHO, LUIZ SERGIO F.; BENSENOR, ISABELA M.; NOGUEIRA, ANA C. C.; DUNCAN, BRUCE B.; SCHMIDT, MARIA I.; BLAHA, MICHAEL J.; TOTH, PETER P.; JONES, STEVEN R.; SANTOS, RAUL D.; LOTUFO, PAULO A.; et al. Increased particle size of triacylglycerol-enriched remnant lipoproteins, but not their plasma concentration or lipid content, augments risk prediction of incident type 2 diabetes. Diabetologia, v. 64, n. 2, . (13/07607-8)
SIDARTA-OLIVEIRA, DAVI; JARA, CARLOS POBLETE; FERRUZZI, ADRIANO J.; SKAF, MUNIR S.; VELANDER, WILLIAM H.; ARAUJO, ELIANA P.; VELLOSO, LICIO A.. SARS-CoV-2 receptor is co-expressed with elements of the kinin-kallikrein, renin-angiotensin and coagulation systems in alveolar cells. SCIENTIFIC REPORTS, v. 10, n. 1, . (13/08293-7, 13/07607-8)
BUENO, LARISSA C. M.; PAIM, LAYDE R.; MININ, EDUARDA O. Z.; DA SILVA, LUIS MIGUEL; MENDES, PAULO R.; KIYOTA, TATIANA A.; SCHREIBER, ANGELICA Z.; BOMBASSARO, BRUNA; MANSOUR, ELI; MORETTI, MARIA LUIZA; et al. Increased Serum Mir-150-3p Expression Is Associated with Radiological Lung Injury Improvement in Patients with COVID-19. Viruses-Basel, v. 14, n. 7, p. 11-pg., . (17/23563-1, 13/07607-8)
NOGUEIRA, PEDRO A. S.; MOURA-ASSIS, ALEXANDRE; ZANESCO, ARIANE M.; BOMBASSARO, BRUNA; GALLO-FERRAZ, ANA L.; SIMOES, MARCELA R.; ENGEL, DAIANE F.; RAZOLLI, DANIELA S.; GASPAR, JOANA M.; DONATO JUNIOR, JOSE; et al. The orphan G protein-coupled receptor, GPR139, is expressed in the hypothalamus and is involved in the regulation of body mass, blood glucose, and insulin. Neuroscience Letters, v. 792, p. 8-pg., . (20/01318-8, 13/07607-8, 18/14818-9)
SACCON, TATIANA DANDOLINI; MOUSOVICH-NETO, FELIPPE; LUDWIG, RAISSA GUIMARAES; CARREGARI, VICTOR CORASOLLA; DOS ANJOS SOUZA, ANA BEATRIZ; DOS PASSOS, AMANDA STEPHANE CRUZ; MARTINI, MATHEUS CAVALHEIRO; BARBOSA, PRISCILLA PASCHOAL; DE SOUZA, GABRIELA FABIANO; MURARO, STEFANIE PRIMON; et al. SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner. NATURE COMMUNICATIONS, v. 13, n. 1, p. 15-pg., . (20/08716-9, 20/04558-0, 19/05155-9, 21/10373-5, 13/07607-8, 20/04919-2, 20/04746-0, 17/01184-9, 17/23920-9, 16/24163-4, 16/00194-8, 18/21635-8, 19/00098-7, 20/05040-4, 17/08264-8, 20/04579-7, 19/26119-0, 19/04726-2, 20/04583-4, 20/15959-5)
DORIGHELLO, GABRIEL G.; ASSIS, LEANDRO H. P.; RENTZ, THIAGO; MORARI, JOSEANE; SANTANA, MONIQUE F. M.; PASSARELLI, MARISA; RIDGWAY, NEALE D.; VERCESI, ANIBAL E.; OLIVEIRA, HELENA C. F.. Novel Role of CETP in Macrophages: Reduction of Mitochondrial Oxidants Production and Modulation of Cell Immune-Metabolic Profile. ANTIOXIDANTS, v. 11, n. 9, p. 17-pg., . (13/07607-8, 17/17728-8, 17/02903-9, 19/18431-4, 21/02401-9, 17/03402-3)

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ELETROESTIMULADOR GÁSTRICO PARA CONTROLE DE PESO PCT/BR2021/050460 - PNP Soluções em Bioenergia LTDA ; Universidade Estadual de Campinas (UNICAMP) . Raquel Franco Leal ; Danilo Carvalho Grael ; Lício Augusto Velloso ; Fábio Henrique Mendonça Chaim - October 2021, 21