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The effect of a cranberry gel on dentine submitted to erosive challenge

Grant number: 12/16295-7
Support Opportunities:Regular Research Grants
Duration: May 01, 2013 - April 30, 2015
Field of knowledge:Health Sciences - Dentistry
Principal Investigator:Heitor Marques Honório
Grantee:Heitor Marques Honório
Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil


The aim of this study is to evaluate the in situ effect of a Cranberry gel over dentine submitted to a erosive challenge. This crossover doble-blinded study will be performed in 2 phases of 5 days each. For that purpose, 10 volunteers will wear 2 palatal devices (1 for each phase) with 4 dentin specimens divided into 2 groups: First Phase: G1 - Erosive challenge (Coca-cola®) over dentine without any previous treatment; G2 - Erosive challenge over dentine previously treated with Cranberry gel; and Second Phase: G3 - Erosive challenge over dentine previously treated with a gel withot any active principle; G4 - Erosive challenge over dentine previously treated with Clorexidine gel. Each device will be immersed into the acid beverage, 3 times daily for 5 minutes during 5 days. The surface microhardness change percentage (%SMC) and profilometry will be used to quantify the dentin alteratons. If the data pass trhough normality and homogenity tests, Repeated Measures Analisys os Variance followed by Tukey test will be performed for both studied response variables (p<0,05). (AU)

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