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Investigation of the characteristics of malocclusion in children with juvenile systemic lupus erythematosus: clinical and volumetric magnetic resonance imaging study

Grant number: 12/16953-4
Support Opportunities:Regular Research Grants
Duration: December 01, 2012 - November 30, 2013
Field of knowledge:Health Sciences - Dentistry - Orthodontics
Principal Investigator:André Luiz Ferreira Costa
Grantee:André Luiz Ferreira Costa
Host Institution: Pró-Reitoria de Pós-Graduação, Pesquisa e Extensão. Universidade Cidade de São Paulo (UNICID). São Paulo , SP, Brazil
Associated researchers: Flávio Augusto Cotrim-Ferreira ; Rívea Inês Ferreira ; Simone Appenzeller


The pediatric rheumatic diseases are considered rare illnesses since affect less than other children's diseases. However, they are associated with high morbidity and high financial and social impact, causing physical disability and functional, and affecting the quality of life of patients. Among the lupus erythematosus clinical manifestations are fever, arthralgia, arthritis, myalgia, lymphadenopathy, weight loss and anemia. The decrease in muscle strength, and / or atrophy, may be a symptom of the disease, but may also occur as a complication of treatment of prolonged use of corticosteroids. Up to the present time, it is not known the influence of the disease in the etiology of malocclusion and the facial pattern in these subjects. There is a lack of studies to investigate the influence of steroid treatment for facial muscles in these patients. In this study, we propose to describe the malocclusion in individuals with systemic lupus erythematosus in a Rheumatology Children center, with clinical orthodontic evaluation and magnetic resonance imaging using volumetry of some mastication muscles. This study will pave the way for further collaborative projects and the beginning of a UNICID Research Group at School of Medicine, UNICAMP. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MONTESINOS, GONZALO ANDRE; DE CASTRO LOPES, SERGIO LUCIO PEREIRA; TRIVINO, TARCILA; SANCHEZ, JOSE ANDRES; MAEDA, FERNANDO AKIO; DE FREITAS, CLAUDIO FROES; FERREIRA COSTA, ANDRE LUIZ. Subjective analysis of the application of enhancement filters on magnetic resonance imaging of the temporomandibular joint. ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, v. 127, n. 6, p. 552-559, . (12/16953-4)
DE ANDRADE LOIOLA, MARLOS EURIPEDES; FUZIY, ACACIO; HIGA, RODRIGO HITOSHI; FUKUJI FUZIY, CESAR HENRIQUE; GANDINI JUNIOR, LUIZ GONZAGA; FERREIRA COSTA, ANDRE LUIZ. In vivo three-dimensional cephalometric landmarks using CBCT for assessment of condylar volume and surface in individuals with Class I, II, and III malocclusions. CRANIO-THE JOURNAL OF CRANIOMANDIBULAR PRACTICE, . (12/16953-4)
AMORIM, MARIAN Y.; ALVES, MONICA G. O.; ALMEIDA, JANETE D.; MONTESINOS, GONZALO A. P.; COSTA, ANDRE L. F.; LOPES, SERGIO L. P. DE C.. Inclination of the condylar long axis is not related to temporomandibular disc displacement. JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY, v. 10, n. 1, . (12/16953-4)

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