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RANDOMIZED TRIAL TO COMPARE TWO METHODS FOR SCLEROTHERAPY IN RETICULAR VEINS AND TELANGIECTASIAS IN LOWER LIMB.

Grant number: 12/11034-0
Support Opportunities:Regular Research Grants
Duration: September 01, 2012 - February 28, 2015
Field of knowledge:Health Sciences - Medicine - Surgery
Principal Investigator:MARCONE LIMA SOBREIRA
Grantee:MARCONE LIMA SOBREIRA
Host Institution: Faculdade de Medicina (FMB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
Associated researchers:Matheus Bertanha

Abstract

Introduction: The lower limb varicose veins have an estimated overall prevalence of 57.5% women and 80 to 90% when searching for cosmetic varicose veins among women. Varicose veins are considered cosmetic frequent complaint in the office of Angiologist and Vascular Surgeon and is a feature not present pain. There are numerous techniques for treating varicose veins aesthetic, among the most common include the chemical sclerotherapy which aims to endothelial injury and obliteration of the vessels sclerotic. To reticular varicose veins there is no consensus and there are few publications on the treatment escleroterápico alternative to surgical procedure, which justifies this work. Objective: To evaluate two methods of chemical sclerotherapy as a treatment for telangiectasias and reticular veins in the lower limbs in an objective and subjective quantification by for photos. It will be also assessed the safety of methods for the occurrence of adverse events. Methods: Prospective, controlled, randomized, double-blind. The sample of convenience and will be continued. This will include 200 legs randomized independently. The treatment area was defined as the posterior knee limited by anatomically rectangle: 25cm and 5cm planting row after tibial crest width of 10cm and 40cm length (area 400cm2) using the square of patterned paper. The treatment will be performed in a single session in the designated area to eliminate all reticular veins and telangiectasias. The area is imaged and re-evaluated quantitatively on days 0, 21 and 60 after application. The quantification is made with a square of plastic with circular marks with 2mm diameter, equidistant 3mm. Will be undertaken in the statistical analysis of results. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BERTANHA, MATHEUS; YOSHIDA, WINSTON B.; BUENO DE CAMARGO, PAULA A.; MOURA, REGINA; DE PAULA, DENIA REIS; PADOVANI, CARLOS R.; SOBREIRA, MARCONE L.. Polidocanol Plus Glucose Versus Glucose Alone for the Treatment of Telangiectasias: Triple Blind, Randomised Controlled Trial (PG3T). EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, v. 61, n. 1, p. 128-135, . (12/11034-0)

Please report errors in scientific publications list by writing to: cdi@fapesp.br.