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Identification and characterization of human herpesvirus 8 (HHV-8) in São Paulo, Brazil

Abstract

The present work has the aim to: a) identify and characterize HHV-8 infection in São Paulo, Brazil, searching for DNA sequences by PCR in PBMC, saliva, semen, vaginal fluid and KS tissue lesions obtained from KS-AIDS patients, from Instituto de Infectologia Emílio Ribas and Casa da AIDS - São Paulo; b) to determine the prevalence of HHV-8 infection in the general population by specific antibodies determination in plasma samples obtained from healthy children and adults, by using immunoenzimatic, immunofluorescence and immunoblotting assays; c) to identify routes of HHV-8 transmission; and finally d) to characterize by genotyping the HHV-8 variants that circulate in São Paulo, Brazil. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MAGRI, MARIANA CAVALHEIRO; LAGE CARBONE, PAULO HENRIQUE; DE LOS SANTOS-FORTUNA, ELIZABETH; CATERINO-DE-ARAUJO, ADELE. A Comparative Study of the Frequency of Antibody and Titers Against Human Herpesvirus 8 Latent and Lytic Antigens in ``At-Risk{''} Individuals and Among Patients With Kaposi's Sarcoma. Journal of Medical Virology, v. 81, n. 7, p. 1292-1297, . (98/13313-5)
CATERINO-DE-ARAUJO‚ A.; CARBONE‚ P.H.L.; MARTINELLI‚ F.L.B.; DE LOS SANTOS-FORTUNA‚ E.; MOREIRA‚ A.A.; SULEIMAN‚ J.; BARRA‚ L.A.C.. Absence of an association between the presence of human herpesvirus 8 antibodies and the development of Kaposi’s sarcoma in HIV-1-infected patients receiving antiretroviral therapy. AIDS, v. 14, n. 10, p. 1455-1457, . (98/13313-5)
ADELE CATERINO-DE-ARAUJO; ELIZABETH SANTOS-FORTUNA; MARIANA CAVALHEIRO MAGRI; FABIANA SCHUELTER-TREVISOL; MARCOS VINICIUS SILVA. Latent human herpesvirus - 8 (HHV-8) infection in female commercial sex workers from Imbituba, Santa Catarina, Brazil. Brazilian Journal of Infectious Diseases, v. 11, n. 1, p. 9-11, . (98/13313-5)
MAGRI, MARIANA CAVALHEIRO; LAGE CARBONE, PAULO HENRIQUE; DE LOS SANTOS-FORTUNA, ELIZABETH; CATERINO-DE-ARAUJO, ADELE. A Comparative Study of the Frequency of Antibody and Titers Against Human Herpesvirus 8 Latent and Lytic Antigens in "At-Risk" Individuals and Among Patients With Kaposi's Sarcoma. Journal of Medical Virology, v. 81, n. 7, p. 6-pg., . (98/13313-5)

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