Development of nanostructured surfaces, by electrochemical techniques, on biomedical titanium alloys

Abstract

In order to improve the cycle of domain and nationalization of science and technology involved in research and development of titanium alloys for biomedical use, the goal of the present Project of Young Researcher, integrating different areas of Knowledge, is getting on biomedical titanium alloys, both already established and newly developed, bioactive nanostructured surfaces with advantages in functionality and compatibility when compared to usual methods of surface modification on the market. In this sense, in the present project is proposed to carry out modifications on the surface of pure Ti grade II (ASTM F67), and the alloys Ti-6Al-4V grade V (ASTM F136), Ti-6Al-7Nb (ASTM F1295 - 05) and Ti-15Mo (ASTM F2066-08), all of which materials will be obtained commercially, in order to determine the best experimental conditions to obtain nanotubes with diameters, lengths, geometries and microstructures optimized for implants applications. On the best alloys and nanostructures obtained, studies of stress corrosion cracking will be performed in media and conditions that simulate physiological environment. Finally, the bioactivity and biocompatibility of the nanostructurated surfaces will be evaluated by deposition of different phases of biological apatite (biomimetic method) on these nanostructures, and then by in vitro culture of osteoblastic cells, responsible for the formation, growth and bone regeneration. (AU)