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Investigation of beta-carbolines alkaloids, tryptamine in ayahuasca in samples of sweat, using the modified solid phase extraction and gas chromatography coupled with nitrogen-phosphorus detector

Abstract

The ²-carbolines alkaloids harmine and harmaline, and the powerful hallucinogen N, N-dimethyltryptamine are typical components of ayahuasca, a typical drink widely used in religious rituals in South America. Currently the use of ayahuasca has spread outside of South America in religious groups the use of tea was established in the United States and several European countries. Due to the increased consumption of this drink, it is important to use validated analytical methods for routine monitoring. This project aims to develop and validate a method for determining the components of Ayahuasca in sweat samples. The extraction of samples of sweat will be performed by modified solid-phase extraction and analyzed by gas chromatography with nitrogen/phosphorous detector. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
TAVARES, LIDIANE; MONEDEIRO, FERNANDA; BORDIN, DAYANNE MOZANER; DE MARTINIS, BRUNO SPINOSA. Investigation of Ayahuasca beta-Carboline Alkaloids and Tryptamine in Sweat Samples from Religious Community Participants by GC-MS. JOURNAL OF ANALYTICAL TOXICOLOGY, v. 44, n. 6, p. 601-609, JUL 2020. Web of Science Citations: 3.
GIUBBINA, FERNANDA F.; SCARAMBONI, CAROLINE; DE MARTINIS, BRUNO S.; GODOY-SILVA, DANIELY; MELLO, IGRAYNE N. P. D.; NOGUEIRA, RAQUEL F. P.; CAMPOS, M. LUCIA A. M. Temporal variation of ethanol in rainwater from the sugar cane belt of Sao Paulo State (Brazil). Atmospheric Environment, v. 216, NOV 1 2019. Web of Science Citations: 0.
GIUBBINA, FERNANDA F.; SCARAMBONI, CAROLINE; DE MARTINIS, BRUNO S.; GODOY-SILVA, DANIELY; NOGUEIRA, RAQUEL F. P.; CAMPOS, M. LUCIA A. M. A simple method for simultaneous determination of acetaldehyde, acetone, methanol, and ethanol in the atmosphere and natural waters. ANALYTICAL METHODS, v. 9, n. 19, p. 2915-2922, MAY 21 2017. Web of Science Citations: 7.

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