Evaluation of hypertriglyceridemia in hospitalized horses and the use of clinical nutrition as a support in the treatment

Abstract

The lack of feeding in some instances like pathologies or hospitalization may affect all the body systems and these conditions can intervene on therapy response or patient recovery. The increase of serial triglycerides concentration (>150mg/dL) can cause several pathological complications, specifically hyperlipemia, in which the animal may have weight loss, lethargy, colic and, in some cases, death. The treatment of hyperlipemia depends on the treatment of concurrent diseases and supply nutrition. Glucoses solutions (50%) and amino acids (10%) by parental way are the energy sources most common. The prognostic is reserved to grave, by this conditions the monitoring of serial triglycerides values and by using a preventive therapy, the prognostic may be reversed and even the time necessary to recovery and hospitalization may be minimized. The objective of this study is to compare the utilization of parenteral solutions reached in amino acids and glucose in animals that presents hyperlipidemia in relations of the standard treatment, without parenteral nutrition. Two groups of horses will be used for this project, consisting in 20 horses, patients of HOVET with triglycerides >150mg/dL. Daily doses of triglycerides and glucose will be taken by 10 animals (control group ), without treatment or handling interference. The experimental group will receive a partial parenteral nutrition composed by glucose and amino acids until normalization of serial triglycerides values. The intensity of hypertriglyceridemia and time of recovery will be evaluated in both groups in order to establish the feasibility and possible complications of parenteral nutrition as a form of nutritional supplementation in animals with hyperlipemia. (AU)