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Study of cytotoxic and genotoxic potential of Solanum lycocarpum and their majoritary compounds and their influence on genotoxicity induced by different mutagens

Grant number: 11/05732-4
Support Opportunities:Regular Research Grants
Duration: June 01, 2011 - May 31, 2013
Field of knowledge:Biological Sciences - Genetics - Mutagenesis
Principal Investigator:Denise Crispim Tavares Barbosa
Grantee:Denise Crispim Tavares Barbosa
Host Institution: Pró-Reitoria Adjunta de Pesquisa e Pós-Graduação. Universidade de Franca (UNIFRAN). Franca , SP, Brazil
Articles published in Agência FAPESP Newsletter about the research grant:
Articles published in other media outlets (0 total):
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Scientific publications (9)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
NICOLELLA, HELOIZA DINIZ; DE OLIVEIRA, POLLYANNA FRANCIELLI; MUNARI, CARLA CAROLINA; DIAS COSTA, GIZELA FALEIROS; MOREIRA, MONIQUE RODRIGUES; SOLA VENEZIANI, RODRIGO CASSIO; TAVARES, DENISE CRISPIM. Differential effect of manool - A diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells. Food and Chemical Toxicology, v. 72, p. 8-12, . (13/22769-4, 11/05732-4)
DE MELO, NATHALYA I.; MANTOVANI, ANDRE L. L.; DE OLIVEIRA, POLLYANNA F.; GROPPO, MILTON; DA SILVA FILHO, ADEMAR A.; RODRIGUES, VANDERLEI; CUNHA, WILSON R.; TAVARES, DENISE C.; MAGALHAES, LIZANDRA G.; CROTTI, ANTONIO E. M.. Antischistosomal and Cytotoxic Effects of the Essential Oil of Tetradenia riparia (Lamiaceae). NATURAL PRODUCT COMMUNICATIONS, v. 10, n. 9, p. 1627-1630, . (11/05732-4, 09/15207-4)
WAKABAYASHI, KAMILA A. L.; DE MELO, NATHALYA I.; AGUIAR, DANIELA P.; DE OLIVEIRA, POLLYANNA F.; GROPPO, MILTON; DA SILVA FILHO, ADEMAR A.; RODRIGUES, VANDERLEI; CUNHA, WILSON R.; TAVARES, DENISE C.; MAGALHAES, LIZANDRA G.; et al. Anthelmintic Effects of the Essential Oil of Fennel (Foeniculum vulgare Mill., Apiaceae) against Schistosoma mansoni. CHEMISTRY & BIODIVERSITY, v. 12, n. 7, p. 1105-1114, . (11/05732-4, 09/15207-4)
ACESIO, NATHALIA OLIVEIRA; DE OLIVEIRA, POLLYANNA FRANCIELLI; PEREIRA MASTROCOLA, DAIANE FERNANDA; DE SOUZA LIMA, ILDERCILIO MOTA; MUNARI, CARLA CAROLINA; FERREIRA LUCATTI SATO, VANIA LUIZA; SILVA SOUZA, ANDRESSA APARECIDA; BOCALON FLAUZINO, LUZIO GABRIEL; CUNHA, WILSON ROBERTO; TAVARES, DENISE CRISPIM. Modulatory Effect of Betulinic Acid on the Genotoxicity Induced by Different Mutagens in V79 Cells. Evidence-based Complementary and Alternative Medicine, . (11/05732-4, 12/16182-8)
MUNARI, CARLA CAROLINA; DE OLIVEIRA, POLLYANNA FRANCIELLI; LIMA CAMPOS, JACQUELINE COSTA; LIMA MARTINS, SABRINA DE PAULA; DA COSTA, JULIANA CARVALHO; BASTOS, JAIRO KENUPP; TAVARES, DENISE CRISPIM. Antiproliferative activity of Solanum lycocarpum alkaloidic extract and their constituents, solamargine and solasonine, in tumor cell lines. Journal of Natural Medicines, v. 68, n. 1, p. 236-241, . (09/15871-1, 11/05732-4)
DAMASCENO, JAQUELINE LOPES; DE OLIVEIRA, POLLYANNA FRANCIELLI; MIRANDA, MARIZA ABREU; LIMA, MARINA; BASTOS, JAIRO KENUPP; TAVARES, DENISE CRISPIM. Antigenotoxic and Antioxidant Properties of Solanum cernuum and Its Alkaloid, Cernumidine. BIOLOGICAL & PHARMACEUTICAL BULLETIN, v. 39, n. 6, p. 920-926, . (12/00715-7, 11/05732-4, 12/07946-4)
MUNARI, CARLA CAROLINA; DE OLIVEIRA, POLLYANNA FRANCIELLI; DE SOUZA LIMA, ILDERCILIO MOTA; LIMA MARTINS, SABRINA DE PAULA; DA COSTA, JULIANA DE CARVALHO; BASTOS, JAIRO KENUPP; TAVARES, DENISE CRISPIM. Evaluation of cytotoxic, genotoxic and antigenotoxic potential of Solanum lycocarpum fruits glicoalkaloid extract in V79 cells. Food and Chemical Toxicology, v. 50, n. 10, p. 3696-3701, . (09/15871-1, 11/05732-4)
DAMASCENO, JAQUELINE L.; OLIVEIRA, POLLYANNA F.; MIRANDA, MARIZA A.; LEANDRO, LUIS F.; ACESIO, NATHALIA O.; OZELIN, SAULO D.; BASTOS, JAIRO K.; TAVARES, DENISE C.. Protective effects of Solanum cernuum extract against chromosomal and genomic damage induced by methyl methanesulfonate in Swiss mice. BIOMEDICINE & PHARMACOTHERAPY, v. 83, p. 1111-1115, . (12/00715-7, 11/05732-4, 12/07946-4)
MUNARI, CARLA CAROLINA; DE OLIVEIRA, POLLYANNA FRANCIELLI; LEANDRO, LUIS FERNANDO; PIMENTA, LEANDRA MARA; FERREIRA, NATALIA HELEN; DA COSTA, JULIANA DE CARVALHO; BASTOS, JAIRO KENUPP; TAVARES, DENISE CRISPIM. In Vivo Assessment of Genotoxic, Antigenotoxic and Anticarcinogenic Activities of Solanum lycocarpum Fruits Glycoalkaloidic Extract. PLoS One, v. 9, n. 11, . (09/15871-1, 11/05732-4)

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