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Optimizing trypanosomatid agents by integration of in silico, calorimetry and cell-based assays

Articles published in Agência FAPESP Newsletter about the research grant:
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (7)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PROKOPCZYK, IGOR M.; RIBEIRO, JEAN F. R.; SARTORI, GERALDO R.; SESTI-COSTA, RENATA; SILVA, JOAO S.; FREITAS, RENATO F.; LEITAO, ANDREI; MONTANARI, CARLOS A.. Integration of methods in cheminformatics and biocalorimetry for the design of trypanosomatid enzyme inhibitors. Future Medicinal Chemistry, v. 6, n. 1, p. 17-33, . (11/01893-3)
SANGI, DIEGO P.; COMINETTI, MARCIA R.; BECCENERI, AMANDA B.; RESENDE, FLAVIA A.; VARANDA, ELIANA A.; MONTANARI, CARLOS A.; PAIXAO, MARCIO W.; CORREA, ARLENE G.. Molecular Design, Synthesis and Evaluation of 2,3-Diarylquinoxalines as Estrogen Receptor Ligands. Medicinal Chemistry, v. 11, n. 8, p. 736-746, . (13/07600-3, 11/01893-3, 13/50680-8)
KENNY, PETER W.; LEITAO, ANDREI; MONTANARI, CARLOS A.. Ligand efficiency metrics considered harmful. Journal of Computer-Aided Molecular Design, v. 28, n. 7, p. 699-710, . (11/20572-3, 11/01893-3)
SOARES, FABYANA A.; SESTI-COSTA, RENATA; DA SILVA, JOAO SANTANA; DE SOUZA, MARIA CECILIA B. V.; FERREIRA, VITOR F.; SANTOS, FERNANDA DA C.; MONTEIRO, PATRICIA A. U.; LEITAO, ANDREI; MONTANARI, CARLOS A.. Molecular design, synthesis and biological evaluation of 1,4-dihydro-4-oxoquinoline ribonucleosides as TcGAPDH inhibitors with trypanocidal activity. Bioorganic & Medicinal Chemistry Letters, v. 23, n. 16, p. 4597-4601, . (11/07025-3, 11/01893-3)
KENNY, PETER W.; MONTANARI, CARLOS A.; PROKOPCZYK, IGOR M.; SALA, FERNANDA A.; SARTORI, GERALDO RODRIGUES. Automated molecule editing in molecular design. Journal of Computer-Aided Molecular Design, v. 27, n. 8, p. 655-664, . (11/20572-3, 11/01893-3)
WIGGERS, HELTON J.; ROCHA, JOSMAR R.; FERNANDES, WILLIAM B.; SESTI-COSTA, RENATA; CARNEIRO, ZUMIRA A.; CHELESKI, JULIANA; DA SILVA, ALBERICO B. F.; JULIANO, LUIZ; CEZARI, MARIA H. S.; SILVA, JOAO S.; et al. Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay. PLoS Neglected Tropical Diseases, v. 7, n. 8, . (11/01893-3)
SANTORO, ADRIANA LEANDRA; CARRILHO, EMANUEL; LANCAS, FERNANDO MAURO; MONTANARI, CARLOS ALBERTO. Quantitative structure-retention relationships of flavonoids unraveled by immobilized artificial membrane chromatography. European Journal of Pharmaceutical Sciences, v. 88, p. 147-157, . (11/01893-3)

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