Advanced search
Start date

Obtaining anthocyanins, carotenoids, flavonoids, volatile oils, and tocotrienols by supercritical technology: process parameters and chemical characterization of extracts


Obtaining bioactive compounds from biological matrices by supercritical extraction, a green technology with many advantages is technically feasible for several biological matrices. Supercritical technology is viable for the production of ingredients for the food, cosmeceuticals and pharmaceuticals industries. In Brazil, the quantity and quality of research in this area are significant. But in our country there are no industries employing this technology for the production of extracts. One reason is association of this technology with higher investments. Studies done at LASEFI/DEA/FEA/UNICAMP have shown that this technology is economically feasible in our country for the production of bioactive extracts. Aiming to spread to the Productive Sector the advantages of supercritical technology we intend to develop a systematic study on the scaling-up to obtain plant extracts with antioxidant activity and to characterize these extracts. The studies of scale-up will be conducted using two extraction units: (1) Unit SFE 2×1L assembled in LASEFI with support from CNPq (Call MCT/CNPq 02/2006 - Universal; registration 472023/2006-3) and (2) unit SFE 2×5L obtained with support from the project PITE - FAPESP 05/60485-1/. The use of two extraction units will allow the transposition of data from laboratory scale (extracting maximum volume equal to 300 mL) for a semi-pilot and later to a pilot scale. The extracts will be characterized with respect to their chemical composition and antioxidant activity; thus, these parameters will be used for the quality control of the process. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
Articles published in other media outlets (0 total):
More itemsLess items

Scientific publications (10)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SANTOS, DIEGO T.; ALBARELLI, JULIANA Q.; ROSTAGNO, MAURICIO A.; ENSINAS, ADRIANO V.; MARECHAL, FRANCOIS; MEIRELES, M. ANGELA A.. New proposal for production of bioactive compounds by supercritical technology integrated to a sugarcane biorefinery. Clean Technologies and Environmental Policy, v. 16, n. 7, SI, p. 1455-1468, . (12/19304-7, 13/15049-5, 12/10685-8, 10/16485-5, 09/17234-9)
ZABOT, GIOVANI L.; MORAES, MOYSES N.; PETENATE, ADEMIR J.; MEIRELES, M. ANGELA A.. Influence of the bed geometry on the kinetics of the extraction of clove bud oil with supercritical CO2. JOURNAL OF SUPERCRITICAL FLUIDS, v. 93, n. SI, p. 56-66, . (09/17234-9, 11/23665-2)
ALBARELLI, J. Q.; MIAN, A.; SANTOS, D. T.; ENSINAS, A. V.; MARECHAL, F.; MEIRELES, M. A. A.. MULTI-OBJECTIVE OPTIMIZATION OF SUPERCRITICAL WATER GASIFICATION OF LEFTOVER BRAZILIAN GINSENG ROOTS AFTER PHYTOCHEMICAL RECOVERY STEPS. Brazilian Journal of Chemical Engineering, v. 34, n. 3, p. 841-850, . (12/19304-7, 12/10685-8, 15/06954-1, 10/16485-5, 09/17234-9, 13/18114-2)
ALBUQUERQUE, CAROLINA L. C.; MEIRELES, M. ANGELA A.. Defatting of annatto seeds using supercritical carbon dioxide as a pretreatment for the production of bixin: Experimental, modeling and economic evaluation of the process. JOURNAL OF SUPERCRITICAL FLUIDS, v. 66, n. SI, p. 86-95, . (09/17234-9)
J. Q. ALBARELLI; A. MIAN; D. T. SANTOS; A. V. ENSINAS; F. MARÉCHAL; M. A. A. MEIRELES. Multi-objective Optimization of Supercritical Water Gasification of Leftover Brazilian Ginseng Roots After Phytochemical Recovery Steps. Brazilian Journal of Chemical Engineering, v. 34, n. 3, p. 841-850, . (10/16485-5, 09/17234-9, 15/06954-1, 13/18114-2, 12/19304-7, 12/10685-8)
VARDANEGA, RENATA; CARVALHO, PEDRO I. N.; ALBARELLI, JULIANA Q.; SANTOS, DIEGO T.; MEIRELES, ANGELA A.. Techno-economic evaluation of obtaining Brazilian ginseng extracts in potential production scenarios. FOOD AND BIOPRODUCTS PROCESSING, v. 101, p. 45-55, . (12/19304-7, 15/06954-1, 12/10685-8, 10/16485-5, 09/17234-9, 13/18114-2)
SANTOS, DIEGO TRESINARI; DE ALMEIDA MEIRELES, MARIA ANGELA. Developing novel one-step processes for obtaining food-grade O/W emulsions from pressurized fluid extracts: processes description, state of the art and perspectives. FOOD SCIENCE AND TECHNOLOGY, v. 35, n. 4, p. 579-587, . (12/10685-8, 12/19304-7, 10/16485-5, 09/17234-9)
RODRIGUES, LIARA M.; ALCAZAR-ALAY, SYLVIA C.; PETENATE, ADEMIR J.; MEIRELES, MARIA ANGELA A.. Bixin extraction from defatted annatto seeds. COMPTES RENDUS CHIMIE, v. 17, n. 3, p. 268-283, . (09/17234-9, 12/10685-8)
FARIAS-CAMPOMANES, ANGELA M.; ROSTAGNO, MAURICIO A.; MEIRELES, M. ANGELA A.. Production of polyphenol extracts from grape bagasse using supercritical fluids: Yield, extract composition and economic evaluation. JOURNAL OF SUPERCRITICAL FLUIDS, v. 77, p. 70-78, . (09/17234-9)
ROSA, M. THEREZA M. G.; SILVA, ERIC KEVEN; SANTOS, DIEGO T.; PETENATE, ADEMIR J.; MEIRELES, M. ANGELA A.. Obtaining annatto seed oil miniemulsions by ultrasonication using aqueous extract from Brazilian ginseng roots as a biosurfactant. Journal of Food Engineering, v. 168, p. 68-78, . (09/17234-9, 12/10685-8, 12/19304-7, 10/16485-5)

Please report errors in scientific publications list by writing to:
Filed patent(s) as a result of this research project

MÉTODO E SISTEMA PARA RECONHECIMENTO E CLASSIFICAÇÃO DE OBJETOS EM AMBIENTES SEMI CONTROLADOS BR1120120204173 - Universidade Estadual de Campinas (UNICAMP) . Anderson de Rezende Rocha - March 2010, 03

PROCESSO DE OBTENÇÃO DE UM EXTRATO A PARTIR DE PFAFFIA GLOMERATA BR1020130128961 - Universidade Estadual de Campinas (UNICAMP) . Maria Angela de Almeida Meireles ; Renata Vardenaga ; Diego Tresinari dos Santos - May 2013, 24