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Use of dendritic cells from mice and human pulsed with pVAX vector containing insert for the expression of P10 or P10 synthetic peptide derived from the GP 43 of P. brasiliensis, as vaccine strategy against paracoccidioidomycosis

Grant number: 09/15823-7
Support Opportunities:Regular Research Grants
Duration: January 01, 2010 - December 31, 2011
Field of knowledge:Biological Sciences - Microbiology - Applied Microbiology
Principal Investigator:Carlos Pelleschi Taborda
Grantee:Carlos Pelleschi Taborda
Host Institution: Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE AMORIM, JULIANA; MAGALHAES, ADRIANA; MUNOZ, JULIAN ESTEBAN; RITTNER, GLAUCE M. G.; NOSANCHUK, JOSHUA D.; TRAVASSOS, LUIZ R.; TABORDA, CARLOS P.. DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis induces long-term protection in presence of regulatory T cells. Microbes and Infection, v. 15, n. 3, p. 181-191, . (11/17267-4, 09/15823-7, 10/51423-0)
RITTNER, GLAUCE M. G.; MUNOZ, JULIAN E.; MARQUES, ALEXANDRE F.; NOSANCHUK, JOSHUA D.; TABORDA, CARLOS P.; TRAVASSOS, LUIZ R.. Therapeutic DNA Vaccine Encoding Peptide P10 against Experimental Paracoccidioidomycosis. PLoS Neglected Tropical Diseases, v. 6, n. 2, p. e1519, . (06/50634-2, 07/07588-2, 09/15823-7)
MAGALHAES, A.; FERREIRA, K. S.; ALMEIDA, S. R.; NOSANCHUK, J. D.; TRAVASSOS, L. R.; TABORDA, C. P.. Prophylactic and Therapeutic Vaccination Using Dendritic Cells Primed with Peptide 10 Derived from the 43-Kilodalton Glycoprotein of Paracoccidioides brasiliensis. Clinical and Vaccine Immunology, v. 19, n. 1, p. 23-29, . (09/15823-7, 10/51423-0)
MAYORGA, ORIANA; MUNOZ, JULIAN E.; LINCOPAN, NILTON; TEIXEIRA, ALINE F.; FERREIRA, LUIS C. S.; TRAVASSOS, LUIZ R.; TABORDA, CARLOS P.. The role of adjuvants in therapeutic protection against paracoccidioidomycosis after immunization with the P10 peptide. FRONTIERS IN MICROBIOLOGY, v. 3, . (11/17267-4, 09/15823-7)

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Filed patent(s) as a result of this research project

FORMULAÇÕES FARMACÊUTICAS VACINAIS E SEUS USOS PI1000870-5 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Universidade de São Paulo (USP) ; Universidade Federal de São Paulo (UNIFESP) . Carlos Pelleschi Taborda ; Glauce Mary Gomes Rittner ; Luiz Rodolpho Raja Gabaglia Travassos - March 2010, 12