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Electromyography analysis of temporal and masseter muscles, bite force and masticatory efficiency in individuals treated with antipsychotic and antidepressant drugs compared to non-medicated individuals

Grant number: 09/11174-4
Support Opportunities:Regular Research Grants
Duration: February 01, 2010 - January 31, 2012
Field of knowledge:Biological Sciences - Morphology - Anatomy
Principal Investigator:Simone Cecilio Hallak Regalo
Grantee:Simone Cecilio Hallak Regalo
Host Institution: Faculdade de Odontologia de Ribeirão Preto (FORP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil


Research in literature shows an increase of caries, gingivitis, periodontitis and stomatitis in subjects treated with antipsychotics and antidepressants drugs. However, besides these anticholinergic properties, it is known that antipsychotic drugs and with less intensely, the antidepressant drugs, interfere in all muscles system. It is known that side effects of the use of antipsychotic drugs associated with acute and chronic movement activity such as parkinsonism, akathisia and tardive dyskinesia. Antidepressant medications, classical tricycles, as well as, the new generation, selective inhibitors of serotonin recapitulation have been identified as the cause of muscle side effects similar to antipsychotics drugs. The aim of this study was to analyze the electromyographic activity of masseter and temporal muscles, the bite force and chewing in subjects treated with antipsychotics and antidepressants compared with the control group, because the importance of these functions within the stomatognathic system. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE OLIVEIRA, R. H.; HALLAK, J. E. C.; SIESSERE, S.; DE SOUSA, L. G.; SEMPRINI, M.; DE SENA, M. F.; OSORIO, F. DE L.; NUNES, E. A.; PINTO, J. P.; REGALO, S. C. H.. Electromyographic analysis of masseter and temporal muscles, bite force, masticatory efficiency in medicated individuals with schizophrenia and mood disorders compared with healthy controls. Journal of Oral Rehabilitation, v. 41, n. 6, p. 399-408, . (09/11174-4)

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