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Marine algae as source of metabolites of economical impact

Abstract

In order to survive in a highly competitive environment, marine algae have to develop defense strategies that result in a tremendous diversity of compounds from different metabolic pathways. Recent trends in drug research from natural sources have shown that algae are promising organisms to furnish novel biochemically active compounds. The aim of this project is to study the compounds biosynthesized by algae with potential economic impact in food science, pharmaceutical industry and public health. Emphasis is given to antioxidants, bactericide, antifungal and UV absorber molecules. Macroalgae will be collected at Sao Paulo State marine coastal and assays will be performed at the lab. Extracts with potential activities will be purifies and the chemical structure will be elucidated. (AU)

Articles published in Pesquisa FAPESP Magazine about the research grant:
Versatilidad marina 
Marine versatility 
Articles published in Agência FAPESP Newsletter about the research grant:
Articles published in other media outlets (0 total):
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Scientific publications (8)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ALVES-LIMA, CICERO; CAVACANA, NATALE; TEIXEIRA CHAVES, GUSTAVO ANTONIO; DE LIMA, NATALIA OLIVEIRA; STEFANELLO, ELIEZER; COLEPICOLO, PIO; HOTTA, CARLOS TAKESHI. Reference genes for transcript quantification in Gracilaria tenuistipitata under drought stress. JOURNAL OF APPLIED PHYCOLOGY, v. 29, n. 2, p. 731-740, . (13/05301-9, 10/14893-9, 11/00818-8, 10/50193-1, 13/08574-6)
ROMANO, RENATO LAHOS; LIRIA, CLEBER WANDERLEI; TERSA MACHINI, M.; COLEPICOLO, PIO; ZAMBOTTI-VILLELA, LEONARDO. Cadmium decreases the levels of glutathione and enhances the phytochelatin concentration in the marine dinoflagellate Lingulodinium polyedrum. JOURNAL OF APPLIED PHYCOLOGY, v. 29, n. 2, p. 811-820, . (12/09068-4, 10/50193-1)
SIMAS-RODRIGUES, CNTIA; VILLELA, HELENA D. M.; MARTINS, ALINE P.; MARQUES, LUIZA G.; COLEPICOLO, PIO; TONON, ANGELA P.. Microalgae for economic applications: advantages and perspectives for bioethanol. Journal of Experimental Botany, v. 66, n. 14, SI, p. 4097-4108, . (11/16072-5, 10/50193-1)
MARTINS, ALINE P.; YOKOYA, NAIR S.; COLEPICOLO, PIO. Biochemical Modulation by Carbon and Nitrogen Addition in Cultures of Dictyota menstrualis (Dictyotales, Phaeophyceae) to Generate Oil-based Bioproducts. MARINE BIOTECHNOLOGY, v. 18, n. 3, p. 314-326, . (10/50193-1, 12/19844-1)
PACHECO, BRUNA SILVEIRA; ZIEMANN DOS SANTOS, MARCO AURELIO; SCHULTZE, EDUARDA; MARTINS, ROSIANE MASTELARI; LUND, RAFAEL GUERRA; SEIXAS, FABIANA KOMMLING; COLEPICOLO, PIO; COLLARES, TIAGO; PAULA, FAVERO REISDORFER; PEREIRA DE PEREIRA, CLAUDIO MARTIN. Cytotoxic Activity of Fatty Acids From Antarctic Macroalgae on the Growth of Human Breast Cancer Cells. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, v. 6, . (10/50193-1)
MARTINS, ALINE P.; ZAMBOTTI-VILLELA, LEONARDO; YOKOYA, NAIR S.; COLEPICOLO, PIO. Biotechnological potential of benthic marine algae collected along the Brazilian coast. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, v. 33, p. 316-327, . (10/50193-1, 12/19844-1)
CASSANO, VALERIA; OLIVEIRA, MARIANA C.; CANDELARIA GIL-RODRIGUEZ, MA; SENTIES, ABEL; DIAZ-LARREA, JHOANA; FUJII, MUTUE T.. Morphological and molecular studies on the Brazilian native red seaweed Laurencia oliveirana (Rhodomelaceae, Ceramiales). REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 22, n. 4, p. 838-849, . (10/52244-2, 10/50193-1)
BERNEIRA, LUCAS M.; DE SANTI, IVANDRA I.; DA SILVA, CAROLINE C.; VENZKE, DALILA; COLEPICOLO, PIO; VAUCHER, RODRIGO DE A.; DOS SANTOS, MARCO A. Z.; DE PEREIRA, CLAUDIO M. P.. Bioactivity and composition of lipophilic metabolites extracted from Antarctic macroalgae. Brazilian Journal of Microbiology, v. 52, n. 3, p. 1275-1285, . (10/50193-1)

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