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Inflamatory response in patients with HIV infection/AIDS and sepsis

Grant number: 06/03362-7
Support Opportunities:Regular Research Grants
Duration: October 01, 2006 - December 31, 2008
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:Sigrid de Sousa dos Santos
Grantee:Sigrid de Sousa dos Santos
Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil


Sepsis is a host response to infection characterized by some clinical and laboratorial signals (fever/hypothermia, tachypnea, tachycardia, altered white blood cell count). The assembly of these signals is named systemic inflammatory response syndrome (SIRS), that is neither specific nor sensitive for an infectious cause, mainly in immunosuppressed patients. Early therapy improves the outcome of sepsis patients, and the identification of a sepsis laboratory marker could provide a faster diagnosis for these patients. This study aimed at evaluating the role of C-reactive protein, procalcitonin, interleukin-6, interleukin-10 and tumor necrosis factor-alpha as diagnostic markers of sepsis in patients with HIV infection/AIDS. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SILVA, JR., JOAO MANOEL; DOS SANTOS, SIGRID DE SOUSA. Sepsis in AIDS patients: clinical, etiological and inflammatory characteristics. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, v. 16, . (06/03362-7)

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