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New diagnostic options for enteroaggregative Escherichia coli (EAEC)

Grant number: 23/00712-2
Support Opportunities:Regular Research Grants
Duration: July 01, 2023 - July 31, 2024
Field of knowledge:Biological Sciences - Microbiology - Biology and Physiology of Microorganisms
Convênio/Acordo: University of Münster (WWU)
Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
Principal Investigator:Waldir Pereira Elias Junior
Grantee:Waldir Pereira Elias Junior
Principal researcher abroad: Christian Rüter
Institution abroad: University of Munster, Germany
Principal researcher abroad: Ulrich Dobrindt
Institution abroad: University of Munster, Germany
Host Institution: Instituto Butantan. Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
Associated researchers:Roxane Maria Fontes Piazza
Associated research grant:18/04144-0 - Development of new diagnostic options for Enteroaggregative Escherichia coli as an important diarrheal pathogen, AP.R


In this SPRINT project, cooperating partners from the Butantan Institute and the University of Munster propose to further expand their existing efforts to characterize enteroaggregative Escherichia coli (EAEC) isolates. Genotypic characterizations will be carried out to analyze the diversity of operons that encode the five variants of AAF fimbriae (aggregative adherence fiambriae) using the EAEC collection under study in the ongoing project with FAPESP funding (2018/04410-0). In addition, a latex agglutination-based rapid diagnostic test will be standardized using the large collection of EAEC already sequenced in Münster. In addition, scientific dissemination strategies will be developed as postgraduate courses and seminars and the preparation and publication of scientific articles. (AU)

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