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Biology of Bacteria and Bacteriophages Research Center

Grant number: 21/10577-0
Support Opportunities:Research Grants - Research, Innovation and Dissemination Centers - RIDC
Duration: May 01, 2023 - April 30, 2028
Field of knowledge:Biological Sciences - Biochemistry - Biochemistry of Microorganisms
Principal Investigator:Shaker Chuck Farah
Grantee:Shaker Chuck Farah
Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Pesquisadores principais:
Aline Maria da Silva ; Beny Spira ; Cristiane Rodrigues Guzzo Carvalho ; Cristina Elisa Alvarez Martinez ; Henrique Ferreira ; Marcelo Brocchi ; Marcio Vinicius Bertacine Dias ; Marilis Do Valle Marques ; Regina Lúcia Baldini ; Roberto Kopke Salinas ; Rodrigo da Silva Galhardo ; Sandro Roberto Marana
Associated researchers:Cristiane Rodrigues Guzzo Carvalho ; Cristina Elisa Alvarez Martinez ; Frederico José Gueiros Filho ; Germán Gustavo Sgro ; João Carlos Setubal ; José Freire da Silva Neto ; Leonardo Talachia Rosa ; Marcio Vinicius Bertacine Dias ; Marco Aurélio Takita ; Rita de Cássia Café Ferreira ; Robson Francisco de Souza ; Rodrigo da Silva Galhardo
Associated grant(s):23/15471-0 - Multi-user equipment approved in grant 2021/10577-0: BMG Labtech Clariostar multimode microplate reader, AP.EMU
23/12177-4 - Multi-user equipment approved in grant 2021/10577-0: circular dichroism spectrophotometers JASCO, model J-1500, AP.EMU
23/12239-0 - Multi-user equipment approved in grant 2021/10577-0: PEAQ-ITC (Isothermal Calorimeter), AP.EMU
Associated scholarship(s):24/01290-7 - Characterization of the stress response by alternative sigma factors in Xanthomonas citri, BP.PD
24/03217-5 - Structural studies of the inner membrane subunits of the Xanthomonas citri Type IV Secretion System using NMR spectroscopy and cryoelectron microscopy, BP.PD
23/13894-1 - CryoEM study of the adsorption of a phage to a type IV pilus, BP.DD
+ associated scholarships 24/02648-2 - Development and implementation of the educational project MicroMath, BP.IC
24/01159-8 - Uncovering bacterial-phage interplay by monitoring transcriptomic changes during phage infection., BP.MS
24/03134-2 - A novel domain and the new signaling pathway of DgcP in Pseudomonas aeruginosa, BP.DD
23/13202-2 - Characterization of Xanthomas citri bacteriophage, BP.IC
23/13291-5 - Determining the intrinsic levels of ppGpp across a species and its influence on growth rate and tolerance to antibiotics, BP.DD
23/05679-3 - Characterization of xac4136 gene as a putative Type VI Secretion System effector in Xanthomonas citri, BP.MS
23/14021-1 - Phage endolysins (ELs) as antimicrobial agents to Gram-negative bacteria, BP.PD
23/12063-9 - Dissemination of concepts in microbiology: Impact assessment on basic education., BP.IC
23/09812-0 - Study of the action of Pseudomonas aeruginosa secretion systems and their effectors in co-cultures with Aspergillus fumigatus, BP.IC
23/10731-4 - Implementation of computational infrastructure for NMR spectroscopy, BP.TT
23/11219-5 - Development and implementation of the educational project MicroMath, BP.IC
23/06554-0 - Identification of compounds that interact with DNA gyrase from Mycobacterium tuberculosis through fragment screening, BP.IC
23/06833-6 - Evaluating the role of aconitase in the regulation of FeS synthesis genes in Caulobacter, BP.IC
23/06724-2 - Isolation of Pseudomonas aeruginosa lytic bacteriophages from various natural sources, BP.IC
23/06729-4 - Training of Pseudomonas aeruginosa lytic bacteriophages to overcome bacterial resistance, BP.IC - associated scholarships

Abstract

The CEPID B3 is a network with research hubs based in São Paulo (IQ-USP, ICB-USP), Campinas (IB-UNICAMP, IAC), Ribeirão Preto (FCFRP-USP, FMRP-USP) and Rio Claro (UNESP) that will collaborate to carry out cutting edge basic research into molecular mechanisms that are of prime importance to understand bacterial reproduction, multicellular behavior, competition, colonization and interactions with their eukaryotic hosts and bacteriophages. The acquired knowledge will be used in the search and development of new chemical and biological inhibitors of bacterial growth. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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