Cold chain more intelligent

Abstract

Global vaccine production, excluding as doses against seasonal flu, is approximately 3 billion doses per year. If we focus only on the vaccine market for covid-19, we are already faced with a giant market that is totally dependent on the cold chain. The vaccines being produced in Brazil by Butantan and Fiocruz, Coronovac and Oxford-Astra-Zeneca are thermolabile vaccines, they need a temperature range of 2-8 degrees Celsius to stay active. One of the most challenging steps in the pharmaceutical area when talking about the cold chain is, without a doubt, the logistics, more specifically, the maintenance of temperature and humidity conditions that guarantee the safety and efficacy of the medication. Among the materials most sensitive to breaking the cold chain are vaccines. According to an estimate by the World Health Organization (WHO), about 50% of vaccines produced worldwide deteriorate until reaching their destination, due to failures in temperature control during transport. Industry 4.0 is composed of several blocks, among which we highlight: Industrial IoT, real-time monitoring, predictive maintenance, systems integration, cloud computing and big data. Specifically in the topic of transport and logistics, especially in large industries, a very recurring problem in IoT, and now in Industry 4.0, is the management and control of mobile logistics assets, such as machines, containers, racks and special boxes. In this context, it is necessary to develop a platform, based on the cloud, that allows tracking of the geolocation of assets to identify compliance on trips or in places of interest. Currently Evoy has an online, cloud-based platform, using IoT concepts, which allows: (I) visibility of assets, since it allows finding assets by geolocation, identifying bottlenecks and improving the routing of delivery or collection; (II) monitoring, when it is possible to analyze the behavior and measure the indicators of turnover time, absence and permanence of assets in points of interest; and (III) control, by optimizing the time management of assets with online inventories for agile and accurate decision making. Considering all this context, and all the technology that Evoy already masters, the aim of this project is to expand the product pipeline, adding new tools to the system, aiming at monitoring and controlling temperature and humidity, with intuitive and easy screens. handling, in compliance with the protocols required by Anvisa by the recently published RDC n. 430/2020. This will provide Evoy with an important market expansion, potentially providing great gains for the cold chain's logistics management, providing the delivery of more efficient and safer medicines to patients. (AU)