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Non pharmacological interventions on noncommunicable diseases: the impact of moderate physical activity on Diabetes Mellitus and on Chronic Kidney Disease

Grant number: 19/18738-2
Support Opportunities:Regular Research Grants
Duration: June 01, 2020 - November 30, 2022
Field of knowledge:Health Sciences - Nursing - Medical-Surgical Nursing
Principal Investigator:Maria de Fatima Fernandes Vattimo
Grantee:Maria de Fatima Fernandes Vattimo
Host Institution: Escola de Enfermagem (EE). Universidade de São Paulo (USP). São Paulo , SP, Brazil


Noncommunicable Diseases (NCDs) are the biggest cause of deaths worldwide. Majority of premature deaths from NCDs are linked to tobacco use, unhealthy diet, physical inactivity and harmful use of alcohol. NCDs, like Chronic Kidney Disease (CKD) and Diabetes, are preexisting clinical conditions that are risk factors for complications like drugs nephrotoxicity, as Contrast Nephropathy (CN). Acute nephrotoxic expositions potentialize progression of CKD and Diabetic Nephropathy (DN). CN represents 10% of the hospital acquired Acute Kidney Injury (AKI) and it is the third cause of AKI. Physical activity is considered a non pharmacological intervention that can interfere in the progression of the CKD and CN. Despite of having been published several times, the benefits of the physical activity in CKD and ND are still not well described. The objective of this study is to evaluate the impact of moderate physycal activity on the renal function in diabetic and CKD rats. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SHEILA MARQUES FERNANDES; MIRIAN WATANABE; MARIA DE FÁTIMA FERNANDES VATTIMO. Inflammation: improving understanding to prevent or ameliorate kidney diseases. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 27, . (19/18738-2)
COUTO, SHEILA M. F.; MACHADO, I, DOUGLAS; CONDE, CAROLINA; SILVA, VINICIUS C.; SOUZA, ADRIANA A.; PERES, KARINA B.; BRANDI, BEATRIZ A.; VATTIMO, MARIA DE FATIMA F.. Physical Training Is a Potential Modifier of Risk for Contrast-Induced Acute Kidney Injury in Diabetes Mellitus. BIOMED RESEARCH INTERNATIONAL, v. 2020, . (19/18738-2)

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