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Well-being of college students: effects of mindfulness practice on biologycal rhythmicity markers.


The irregularity in sleep patterns of students and the increased light exposure at night have a negative impact on well-being and health, as evidenced by the phase delay in melatonin synthesis. Melatonin is an endogenous phase marker and, like other rhythms, as activity/rest and body temperature, for example, is a marker of biological rhythmicity: synchronized by light/dark variation, timed by the suprachiasmatic nucleus and determined by the "clock genes" . Mindfulness promotes the development of abilities that can lead to an adjustment in the rhythmic phase of the organism, considering the positive effects of practices on the sleep/wake cycle and the importance of rhythmicity on its regulation. Mindfulness also promotes well-being and minimizes negative effects of stress, such as the production of pro-inflammatory cytokines and cortisol. In this way, the present project aims to evaluate the subjective well-being of university students and to verify the effects of a mindfulness-based intervention on biological markers of rhythmicity, stress and attention. To this end, students from the Federal University of São Paulo, Campi São Paulo and Baixada Santista, will undergo a self-report concerning health, sleep quality, mental health and stress perception. They will then be selected to participate in the Mindfulness-Based Health Promotion program for eight weeks. Measurements will be made before, during and after the intervention to evaluate: the phase adjustment of biological rhythmicity markers (activity / rest, temperature and melatonin); the expression of "clock genes"; the biological response to stress (salivary cortisol and gene expression of proinflammatory cytokines) and attentional response (psychomotor vigilance test). (AU)

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(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
VALLIM, JULIA RIBEIRO DA SILVA; LIMA, GABRIELA SANT'ANA; TSUJI, HELOISA MAYUMI SUYAMA; XYLARAS, BEATRIZ DUARTE PALMA; TUFIK, SERGIO; DEMARZO, MARCELO; D'ALMEIDA, VANIA. Mediation analysis of circadian preferences and other behavioral and sociodemographic factors associated with subjective well-being in undergraduate students. CHRONOBIOLOGY INTERNATIONAL, v. 40, n. 4, p. 13-pg., . (18/18889-8)

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