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SYNTHESIS AND CHARACTERIZATION OF ORGANIC COMPOUNDS WITH POTENTIAL AS NEW DRUGS AGAINST TO CHANNEL IONICOS DYSFUNCTIONS, LEISHMANIA AND ANTI-TUMOUR TREATMENT.

Grant number: 18/00581-7
Support Opportunities:Regular Research Grants
Duration: April 01, 2019 - May 31, 2021
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal Investigator:Eduardo Rene Perez Gonzalez
Grantee:Eduardo Rene Perez Gonzalez
Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil

Abstract

This project deals with the design and synthesis of guanidinas with anti-leishmaniose activity (multitarget) and the investigation of possible targets. Relevant results are expected to deposit patents and high-level scientific publications. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Articles published in other media outlets (0 total):
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MOREIRA, VITOR PARTITE; DA SILVA MELA, MICHELE FERREIRA; DOS ANJOS, LUANA RIBEIRO; SARAIVA, LEONARDO FIGUEIREDO; VELASQUEZ, ANGELA M. ARENAS; KALABA, PREDRAG; FABISIKOVA, ANNA; CLEMENTINO, LEANDRO DA COSTA; AUFY, MOHAMMED; STUDENIK, CHRISTIAN; et al. Novel Selective and Low-Toxic Inhibitor of LmCPB2.8 Delta CTE (CPB) One Important Cysteine Protease for Leishmania Virulence. BIOMOLECULES, v. 12, n. 12, p. 21-pg., . (18/00581-7, 20/04415-4, 16/19289-9, 17/03552-5, 18/23015-7, 21/02595-8)
DA SILVA, SUZANE ROSA; KALABA, PREDRAG; FABISIKOVA, ANNA; ZEHL, MARTIN; DRAGATEVIE, VLADIMIR; DOS ANJOS, LUANA RIBEIRO; NEILL, PHILIP JOHN; WIEDER, MARCUS; PRADO-ROLLER, ALEXANDER; GAJIC, NATALIE; et al. ynthesis and dopamine receptor binding of dihydrexidine and SKF 38393 catecholamine-based analogue. Amino Acids, v. 54, n. 1, . (16/10149-0, 18/00581-7)

Please report errors in scientific publications list by writing to: gei-bv@fapesp.br.