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Native and cultivated passifloras in Brazil: pharmacognostic, chemical and pharmacological evaluation geared to valorization of popular use and development of autochthonous medicines

Grant number: 04/07933-3
Support Opportunities:BIOTA-FAPESP Program - Thematic Grants
Duration: December 01, 2004 - November 30, 2009
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal Investigator:Massayoshi Yoshida
Grantee:Massayoshi Yoshida
Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Pesquisadores principais:
Elfriede Marianne Bacchi ; Marcia Ortiz Mayo Marques

Abstract

The rational and scientific use of medicinal plants from the Brazilian rainforest is currently considered an important scientific and therapeutical alternative, mainly by the great pharmaceutical industries. The genus Passiflora, Passifloraceae, commonly used by the folks in tropical and subtropical regions has already been proven to have potential therapeutical activities. The species Passiflora incarnate has been used in many countries as anxiolytic, sedative and antispasmodic in Brazil. Many phytotherapics (medicines) with Passiflora extracts can be found in the market. However, as no therapeutical activity could yet be suitably proven, there are no scientific data of its efficacy. The present work aims at isolating and biomonitoring the active substances of the extracts of the species. Eventualy the species with proven pharmacological activity will be characterized considering their macroscopic aspects, and the contents of their bioactive substances will also be determined. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
JOSSEARA BERALDO; EDNA TOMIKO MYIAKE KATO. Morfoanatomia de folhas e caules de Passiflora edulis Sims, Passifloraceae. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 20, n. 2, p. 233-239, . (04/07933-3)
WASICKY, ANDRE; HERNANDES, LEANDRO S.; VETORE-NETO, ALBERTO; MORENO, PAULO R. H.; BACCHI, ELFRIEDE MARIANNE; MYIAKE KATO, EDNA TOMIKO; YOSHIDA, MASSAYOSHI. Evaluation of gastroprotective activity of Passiflora alata. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 25, n. 4, p. 407-412, . (04/07933-3)

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