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Effect of systemic or punctual laser on cleft alveolar ridge area grafted with autogenous bone. Analysis by infrared thermography and stereophotogrammetry.

Grant number: 18/07060-2
Support Opportunities:Regular Research Grants
Duration: December 01, 2018 - February 28, 2021
Field of knowledge:Health Sciences - Dentistry - Periodontology
Principal Investigator:Ana Lucia Pompeia Fraga de Almeida
Grantee:Ana Lucia Pompeia Fraga de Almeida
Host Institution: Hospital de Reabilitação de Anomalias Craniofaciais (HRAC). Universidade de São Paulo (USP). Bauru , SP, Brazil
Associated researchers:Leonardo Rigoldi Bonjardim ; Simone Soares


The cleft lip and palate are among the most common face malformations, cause aesthetic cells to leave marks and others when not treated correctly over time, with the functioning of the velopharyngeal mechanism and ear. Lip and palate fissures can be larger and more challenging. The autogenous bone graft is submitted to measurement of vascular filling by the segmented cleft border, and the medial bone preferential to the cortical bone is due to the large quantity of bone cells and their capacity to induce the formation of new bone. Bone graft from the iliac crest has been the material of choice because of its ability to present, at the same time, some characteristics such as postoperative area morbidity, sensory disturbances and claudication, prolonging its hospitalization time and reabsorption greater than 40% not first year after grafting; one of the alternatives would be the removal of a bony bone from the mental foramen. Low-intensity laser has been successfully used in bone regeneration in laboratory studies. Another way to optimize low-intensity laser properties is to use the Intravascular Blood Irradiation (ILIB) method, a safe and effective method that has been used in Russia, China and Iran for more than 20 years. The objective of this study was to evaluate the effect of systemic or punctual laser on the cleft alveolar ridge area grafted with the autogenous bone. A category will based on 42 clinical with cleft lip and palate of 9 to 15 years of the sex which require alveolar bone swarms which are divided into three groups: group 1 (control) - alveolar bone graft in the area of the cleft alveolar ridge ; group 2 (LLB-6J) - bone graft with punctual laser application - 4 points; group 3 (Ilib) - bone graft with application of systemic laser. The laser used in Groups 2 and 3 will be Therapy EC at the wavelength in the infrared (880nm ± 10 nm) and red (660 nm ± 10 nm) respectively, with a power output of 100 mW ± 20%. In the punctual form, 6J per point will be applied in 4 points, and ILIB will be followed for 30 minutes, both at T0L - 24 hours preoperatively, T1L - immediate postoperative, T2L - 24 hours post operative and T3L - 48 hours postoperatively. The postoperative pain will be evaluated based on the subjective responses of the patients, through Visual Analogue Scale at T0EA - 24 hours postoperatively and T1EA - 48 hours postoperatively. The temperature evaluation will be performed by the FLIR Camera T2-T540SC, with 176,800 pixels, sensitivity of 30 mK to 30o, visual camera of 5 Mpixels, 24o 10mm lens and processed with Research IR software. Infrared images will be performed in the following times: T0L - 24 hours preoperatively, T1T - immediate postoperative, T2T - 24 hours postoperatively and T3T - 48 hours postoperatively. The 3D photographs will be performed by Vectra H1 stereophotogrammetry 3D equipment in the following times: T0L - 24 hours preoperatively, T1T - 24 hours postoperatively and T2T - 48 hours postoperatively. (AU)

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