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Extractive Ethanol Fermentation in Pneumatic Bioreactors with Removal by CO2 Stripping Integrated to Recovery Units


The ethanol that accumulates in the broth during the alcoholic fermentation is the main toxic component for yeast, affecting its growth and limiting the industrial ethanol production. In this way, the process is limited to the use of musts with moderate concentrations of fermentable sugars, producing wines with low ethanol concentration (8 to 11ºGL), which requires a large amount of energy for the ethanol recovery by distillation, generating also large volumes of vinasse. One way of minimizing the inhibitory effect is the use of the extractive fermentation, wherein the ethanol is continuously removed from the fermentation broth during the process. The present project proposes to evaluate, experimentally and by simulation, the extractive alcoholic fermentation in pneumatic bioreactors integrated to a stage of ethanol recovery. It will be studied the extraction of the ethanol from the fermentation broth by stripping with CO2 at different temperatures and in three pneumatic bioreactors (bubble column and concentric tube and split airlifts) varying the concentration of substrate in the must, as well as the ethanol recovery from the CO2 stream by absorption. The results will be evaluated in terms of production and productivity in ethanol and will be compared with those obtained in the conventional process without extraction. It is intended to get to the final implementation of the proposal, the protocol of an alternative ethanol production process more productive, which can be the starting point for validation in pilot and industrial scales. (AU)

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Scientific publications (11)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MESTRE, JULIA C.; CERRI, MARCEL O.; ESPERANCA, MATEUS N.; PEDROLLI, DANIELLE B.; BADINO, ALBERTO C.. Aeration step method for k(L)a measurement under growth conditions in pneumatic bioreactors. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, v. 94, n. 7, p. 2327-2332, . (11/23807-1, 18/11405-5, 12/17756-8)
RODRIGUES, KAIO C. S.; VELOSO, IVAN I. K.; CRUZ, ANTONIO J. G.; BERNARDO, ANDRE; BADINO, ALBERTO C.. Ethanol Recovery from Stripping Gas Mixtures by Gas Absorption: Experimental and Modeling. ENERGY & FUELS, v. 33, n. 1, p. 369-378, . (14/26854-9, 18/11405-5)
PEREIRA, RAUBER D.; BADINO, ALBERTO C.; CRUZ, ANTONIO J. G.. Framework Based on Artificial Intelligence to Increase Industrial Bioethanol Production. ENERGY & FUELS, v. 34, n. 4, p. 4670-4677, . (18/11405-5, 18/24460-4)
RODRIGUES, KAIO C. S.; VELOSO, IVAN I. K.; RIBEIRO, MARCELO P. A.; CRUZ, ANTONIO J. G.; BADINO, ALBERTO C.. Mid-infrared spectroscopy as a tool for real-time monitoring of ethanol absorption in glycols. CANADIAN JOURNAL OF CHEMICAL ENGINEERING, v. 99, n. 1, p. 401-409, . (18/11405-5, 14/26854-9)
ALMEIDA, LETICIA P.; SILVA, CAMILA R.; MARTINS, TAISE B.; PEREIRA, RAUBER D.; ESPERANCA, MATEUS N.; CRUZ, ANTONIO J. G.; BADINO, ALBERTO C.. Heat transfer evaluation for conventional and extractive ethanol fermentations: Saving cooling water. JOURNAL OF CLEANER PRODUCTION, v. 304, . (18/11405-5)
ESPERANCA, MATEUS N.; BUFFO, MARIANE M.; MENDES, CAROLINE E.; RODRIGUEZ, GUILHERME Y.; BETTEGA, RODRIGO; BADINO, ALBERTO C.; CERRI, MARCEL O.. inking maximal shear rate and energy dissipation/circulation function in airlift bioreactor. Biochemical Engineering Journal, v. 178, . (18/11405-5, 20/08699-7, 11/23807-1, 12/17756-8)
PEREIRA, RAUBER D.; RODRIGUES, KAIO C. S.; SONEGO, JORGE L. S.; CRUZ, ANTONIO J. G.; BADINO, ALBERTO C.. A New Methodology to Calculate the Ethanol Fermentation Efficiency at Bench and Industrial Scales. Industrial & Engineering Chemistry Research, v. 57, n. 48, p. 16182-16191, . (18/11405-5)
VELOSO, IVAN I. K.; RODRIGUES, KAIO C. S.; SONEGO, JORGE L. S.; CRUZ, ANTONIO J. G.; BADINO, ALBERTO C.. Fed-batch ethanol fermentation at low temperature as a way to obtain highly concentrated alcoholic wines: Modeling and optimization. Biochemical Engineering Journal, v. 141, p. 60-70, . (18/11405-5, 14/26854-9)
BUFFO, MARIANE M.; FERREIRA, ANDRE L. Z.; ALMEIDA, RENATA M. R. G.; FARINAS, CRISTIANE S.; BADINO, ALBERTO C.; XIMENES, EDUARDO A.; LADISCH, MICHAEL R.. ellulolytic enzymes production guided by morphology engineerin. Enzyme and Microbial Technology, v. 149, . (18/11405-5)
VELOSO, IVAN I. K.; RODRIGUES, KAIO C. S.; RIBEIRO, MARCELO P. A.; CRUZ, ANTONIO J. G.; BADINO, ALBERTO C.. Temperature Influence in Real-Time Monitoring of Fed-Batch Ethanol Fermentation by Mid-Infrared Spectroscopy. Industrial & Engineering Chemistry Research, v. 59, n. 41, p. 18425-18433, . (18/11405-5)
LEMOS, DIEGO A.; SONEGO, JORGE L. S.; CRUZ, ANTONIO J. G.; BADINO, ALBERTO C.. Improvement of ethanol production by extractive fed-batch fermentation in a drop column bioreactor. Bioprocess and Biosystems Engineering, v. 43, n. 12, . (18/11405-5)

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