Advanced search
Start date

Synthesis and application of ionic liquids to unveil the chemistry of fermentative processes

Grant number: 17/25490-1
Support Opportunities:Regular Research Grants
Duration: June 01, 2018 - May 31, 2020
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
Principal Investigator:Leandro Wang Hantao
Grantee:Leandro Wang Hantao
Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated researchers:Fernanda Furlan Gonçalves Dias ; Ronei Jesus Poppi


In this research project, we propose the development of a technological solution to investigate the chemistry of fermented beverages by combining ionic liquids (IL), comprehensive two-dimensional gas chromatography (GCxGC), and chemometrics ('artificial inteligence'). Beverage analysis is a demanding task due to the overwhelming quantity of analytes with highly diverse chemical and physical properties that limits the application of traditional protocols. Analytical Chemistry has benefited from the incredible advances in technology of the past decades. Today, the development of highly efficient sorbent phases, capable of extracting a broad diversity of molecules, and the outcome of high-resolution instruments, which produces dense and intrinsically multivariate data, which challenges even the most veteran GC practitioner. Application of ionic liquids in microextractions of organic compounds are now highly effective, due to the unique solvation properties of IL. Also, GCxGC coupled to mass spectrometry (GCxGC-MS) has enabled improved peak capacity separations of many matrices, producing high quality measurements. Furthermore, artificial intelligence-based approaches using chemometric techniques are desperately required to manage and explore such big data. This orthogonal approach is likely the most efficient path for data mining to unveil the complex chemistry of fermentative processes and related applications. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
Articles published in other media outlets (0 total):
More itemsLess items

Scientific publications (9)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FACANALI, ROSELAINE; MAYO MARQUES, MARCIA ORTIZ; HANTAO, LEANDRO WANG. Metabolic Profiling of Varronia curassavica Jacq. Terpenoids by Flow Modulated Two-Dimensional Gas Chromatography Coupled to Mass Spectrometry. SEPARATIONS, v. 7, n. 1, . (17/25490-1)
VIZIOLI, BEATRIZ DE CAROLI; HANTAO, LEANDRO WANG; MONTAGNER, CASSIANA CAROLINA. Drinking water nitrosamines in a large metropolitan region in Brazil. Environmental Science and Pollution Research, v. 28, n. 25, p. 32823-32830, . (14/50951-4, 14/24740-6, 17/25490-1)
DE OLIVEIRA, AMILTON MOREIRA; BALLEN CASTIBLANCO, JULIAN EDUARDO; FLEMING, FELIPE PEREIRA; RAMALHO DE SOUZA, EMANOEL NAZARENO; HANTAO, LEANDRO WANG. Sample Preparation for Solid Petroleum-Based Matrices Based on Direct Matrix Introduction Oriented to Hydrocarbon Profiling. ENERGY & FUELS, v. 34, n. 9, p. 8-pg., . (17/25490-1, 17/00358-3)
BELINATO DE SOUZA, JOAO R.; DIAS, FERNANDA F. G.; CALIMAN, JAQUELINE D.; AUGUSTO, FABIO; HANTAO, LEANDRO W.. Opportunities for green microextractions in comprehensive two-dimensional gas chromatography / mass spectrometry-based metabolomics - A review. Analytica Chimica Acta, v. 1040, p. 1-18, . (11/51896-9, 17/25490-1, 15/05059-9, 16/20547-2)
FERREIRA, VICTOR H. C.; HANTAO, LEANDRO W.; POPPI, RONEI J.. Consumable-free Comprehensive Three-Dimensional Gas Chromatography and PARAFAC for Determination of Allergens in Perfumes. Chromatographia, v. 83, n. 5, . (17/25490-1)
PASSINI, RODRIGO; PIERONE, DANILO; GOBBI, ANGELO L.; HANTAO, LEANDRO W.. Flow Modulated Comprehensive Two-Dimensional Gas Chromatography Part I - Low Duty Cycle Modulation of Hidroprocessed Vegetable Oil. BRAZILIAN JOURNAL OF ANALYTICAL CHEMISTRY, v. 6, n. 24, p. 74-81, . (15/05059-9, 17/25490-1)

Please report errors in scientific publications list using this form.