Support for Research Publications - Articles

• Abstract

  Eukaryotic ribosome biogenesis is an elaborate process during which ribosomal proteins assemble with the pre-rRNA while it is being processed and folded. Hundreds of assembly factors (AF) are required and transiently recruited to assist the sequential remodeling events. One of the most intricate ones is the stepwise removal of the internal transcribed spacer 2 (ITS2), between the 5.8S and…

  The ribosome assembly factor Nop53 has a structural role in the formation of nuclear pre-60S intermediates, affecting late maturation events, PUB.ART

• Abstract

  The objective of this study is to identify whether oxytocin (ot) contributes to the reduction of osteopenia in the femoral neck of rats in periestropause. Animals in irregular estrous cycles received two NaCl injections (0.15 mol/L) or OT (134 ¼g/kg) over a 12-h interval, and after thirty-five days without treatments, the biological sample collection was performed. the oxytocin group (ot)…

  Oxytocin and bone quality in the femoral neck of rats in periestropause, PUB.ART

• Abstract

  Marfan syndrome (MFS) is a connective tissue disease caused by variants in the FBN1 gene. Nevertheless, other genes influence the manifestations of the disease, characterized by high clinical variability even within families. We mapped modifier loci for cardiovascular and skeletal manifestations in the mgloxPneo mouse model for MFS and the synthenic loci in the human genome. Corroborat…

  Is HSPG2 a modifier gene for Marfan syndrome?, PUB.ART

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