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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Interplay among steroids, body condition and immunity in response to long-term captivity in toads

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Autor(es):
Monteiro Titon, Stefanny Christie [1] ; Titon Junior, Braz [1] ; Assis, Vania Regina [1] ; Kinker, Gabriela Sarti [1] ; Carlos Magno Fernandes, Pedro Augusto [1] ; Gomes, Fernando Ribeiro [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Inst Biociencias, Dept Fisiol, Sao Paulo - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: SCIENTIFIC REPORTS; v. 8, NOV 21 2018.
Citações Web of Science: 2
Resumo

Stressful experiences can promote harmful effects on physiology and fitness. However, stress-mediated hormonal and immune changes are complex and may be highly dependent on body condition. Here, we investigated captivity-associated stress effects, over 7, 30, 60, and 90 days on plasma corticosterone (CORT) and testosterone (T) levels, body index, and innate immunity (bacterial killing ability and phagocytosis of peritoneal cells) in toads (Rhinella icterica). Toads in captivity exhibited elevated CORT and decreased T and immunity, without changes in body index. The inter-relationships between these variables were additionally contrasted with those obtained previously for R. schneideri, a related species that exhibited extreme loss of body mass under the same captive conditions. While T and phagocytosis were positively associated in both species, the relationship between CORT and bacterial killing ability was dependent on body index alterations. While CORT and bacterial killing ability were positively associated for toads that maintained body index, CORT was negatively associated with body index in toads that lost body mass over time in captivity. In these same toads, body index was positively associated with bacterial killing ability. These results demonstrate that steroids-immunity inter-relationships arising from prolonged exposure to a stressor in toads are highly dependent on body condition. (AU)

Processo FAPESP: 13/00900-1 - Estudo comparativo das relações entre imunocompetência e níveis plasmáticos de esteróides inter-renais e gonadais em sapos
Beneficiário:Fernando Ribeiro Gomes
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 14/16320-7 - Impactos das mudanças climáticas e ambientais sobre a fauna: uma abordagem integrativa
Beneficiário:Carlos Arturo Navas Iannini
Linha de fomento: Auxílio à Pesquisa - Programa de Pesquisa sobre Mudanças Climáticas Globais - Temático