- Research Grants
The agreement with the University of Glasgow (UoG), Scotland, aims at implementing academic cooperation between researchers from UoG and from the State of São Paulo, Brazil, through the funding of joint research projects.
The present project focuses on vascular oxidative stress as a mechanistic link between macrophage infiltration, matrix metalloproteinase activation and VSMC dysregulation (apoptosis) in atherosclerotic plaque instability. We aim to determine how the vascular redox environment impacts the atherosclerotic plaque phenotype. In particular we will unravel the role of PTPs in this process. (AU)
Recent work in Leishmania examined a key player in the damage sensing, cell cycle progression and DNA repair processes in these organisms. This factor, termed the Rad9-Rad1-Hus1 (9-1-1) complex is a ring-shaped heterotrimeric complex, structurally related to the PCNA clamp and is conserved amongst eukaryotes. Accumulating evidence indicates Leishmania 9-1-1 is central to genome maintena...
The proposed project aims to create a consortium to extend and strengthen the collaborative research between two well-established independently driven research groups from University of Sao Paulo and University of Glasgow. Through visits and exchanges of faculty staff, the consortium will promote the implementation of a critical mass joining resources and skills to conduct research proj...
(Only some records are available in English at this moment)
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