- Research Grants
The agreement with the Weizmann Institute of Science (WIS), Israel, aims at implementing scientific and technological cooperation between researchers from WIS and from the State of São Paulo, through the funding of joint research projects.
Protozoan parasites, which are major human pathogens in both Brazil and Israel, were shown to release extracellular vesicles (EVs) into the host microenvironment, and these are known to modulate the intracellular communication between pathogens and hosts . Although these EVs have been characterized and shown to play important roles in the establishment of infection, specific processes i...
This proposal is aimed to further characterize this important pathway in the developing brain and to understand how it is involved in ASD. The specific objectives include: 1) Further analyze and characterize the complement pathway in the developing brain using mouse models; 2) Expand and validate ASD related variants in the complement pathway; 3) Focus on specific ASD related potentiall...
Our collaborative project aims at understanding how light/dark dependent signals regulate physiologic immune-cell generation and host-defense as part of homeostasis and in response to inflammatory insult. Identificating regulatory mechanisms and key molecules will provide new targets for improving clinical procedures such as stem cell transplantation and immunotherapy. (AU)
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